Search Results - "Heins, Brittany M"

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    Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy by Sareen, Dhruv, Ebert, Allison D, Heins, Brittany M, McGivern, Jered V, Ornelas, Loren, Svendsen, Clive N

    Published in PloS one (19-06-2012)
    “…Spinal muscular atrophy (SMA) is a genetic disorder caused by a deletion of the survival motor neuron 1 gene leading to motor neuron loss, muscle atrophy,…”
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    Journal Article
  2. 2

    Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease by Ebert, Allison D., Barber, Amelia E., Heins, Brittany M., Svendsen, Clive N.

    Published in Experimental neurology (01-07-2010)
    “…Huntington's disease (HD) is an autosomal dominant disorder caused by expansion of polyglutamine repeats in the huntingtin gene leading to loss of striatal and…”
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    Journal Article