Search Results - "Heinrich, N"

Analysis of circulating ceramides and hexosylceramides in patients with coronary artery disease and type II diabetes mellitus by Düsing, Philip, Heinrich, Nadine N, Al-Kassou, Baravan, Gutbrod, Katharina, Dörmann, Peter, Nickenig, Georg, Jansen, Felix, Zietzer, Andreas

“…Abstract Background Cardiovascular disease (CVD) remains the leading cause of death worldwide. The main driving force behind this association is coronary…”
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A phase IIb, open-label, randomized controlled dose ranging multi-centre trial to evaluate the safety, tolerability, pharmacokinetics and exposure-response relationship of different doses of delpazolid in combination with bedaquiline delamanid moxifloxacin in adult subjects with newly diagnosed, uncomplicated, smear-positive, drug-sensitive pulmonary tuberculosis by Dierig, A, Hoelscher, M, Schultz, S, Hoffmann, L, Jarchow-MacDonald, A, Svensson, E M, Te Brake, L, Aarnoutse, R, Boeree, M, McHugh, T D, Wildner, L M, Gong, X, Phillips, Ppj, Minja, L T, Ntinginya, N, Mpagama, S, Liyoyo, A, Wallis, R S, Sebe, M, Mhimbira, F A, Mbeya, B, Rassool, M, Geiter, L, Cho, Y L, Heinrich, N

“…Linezolid is an effective, but toxic anti-tuberculosis drug that is currently recommended for the treatment of drug-resistant tuberculosis. Improved…”
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Measured proton electromagnetic structure deviates from theoretical predictions by Li, R., Sparveris, N., Atac, H., Jones, M. K., Paolone, M., Akbar, Z., Gayoso, C. Ayerbe, Berdnikov, V., Biswas, D., Boer, M., Camsonne, A., Chen, J.-P., Diefenthaler, M., Duran, B., Dutta, D., Gaskell, D., Hansen, O., Hauenstein, F., Heinrich, N., Henry, W., Horn, T., Huber, G. M., Jia, S., Joosten, S., Karki, A., Kay, S. J. D., Kumar, V., Li, X., Li, W. B., Liyanage, A. H., Malace, S., Markowitz, P., McCaughan, M., Meziani, Z.-E., Mkrtchyan, H., Morean, C., Muhoza, M., Narayan, A., Pasquini, B., Rehfuss, M., Sawatzky, B., Smith, G. R., Smith, A., Trotta, R., Yero, C., Zheng, X., Zhou, J.

“…The visible world is founded on the proton, the only composite building block of matter that is stable in nature. Consequently, understanding the formation of…”
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Identifying children with tuberculosis among household contacts in The Gambia by Egere, U., Togun, T., Sillah, A., Mendy, F., Otu, J., Hoelscher, M., Heinrich, N., Hill, P. C., Kampmann, B.

“…SETTING: Greater Banjul Area of the Gambia.OBJECTIVES: To identify co-prevalent tuberculosis (TB) among child contacts of adults with smear-positive TB.DESIGN:…”
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Diagnosis of paediatric TB using Xpert® MTB/RIF Ultra on fresh respiratory samples by Sabi, I., Olomi, W., Nkereuwem, E., Togun, T., Gomez, M. P., Sylla, M., Diarra, B., Sanogo, M., Sichone, E., Mahiga, H., Njeleka, F., Ebonyi, A. O., Egere, U., Ntinginya, N. E., Hoelscher, M., Heinrich, N., Kampmann, B.

“…OBJECTIVE: To evaluate the diagnostic accuracy of Xpert® MTB/RIF Ultra (Ultra) on fresh respiratory samples for the diagnosis of pulmonary TB (PTB) in…”
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Pion electroproduction measurements in the nucleon resonance region by Li, R., Sparveris, N., Atac, H., Jones, M. K., Paolone, M., Akbar, Z., Ali, M., Gayoso, C. Ayerbe, Berdnikov, V., Biswas, D., Boer, M., Camsonne, A., Chen, J.-P., Diefenthaler, M., Duran, B., Dutta, D., Gaskell, D., Hansen, O., Hauenstein, F., Heinrich, N., Henry, W., Horn, T., Huber, G. M., Jia, S., Joosten, S., Karki, A., Kay, S. J. D., Kumar, V., Li, X., Li, W. B., Liyanage, A. H., Mack, D., Malace, S., Markowitz, P., McCaughan, M., Meziani, Z.-E., Mkrtchyan, H., Morean, C., Muhoza, M., Narayan, A., Pasquini, B., Rehfuss, M., Sawatzky, B., Smith, G. R., Smith, A., Trotta, R., Yero, C., Zheng, X., Zhou, J.

“…We report new pion electroproduction measurements in the Δ ( 1232 ) resonance, utilizing the SHMS - HMS magnetic spectrometers of Hall C at Jefferson Lab. The…”
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Pharmacological comparison of muscarinic ligands : Historical versus more recent muscarinic M1-preferring receptor agonists by HEINRICH, Julia N, BUTERA, John A, TSENG, Eugene, UVEGES, Albert J, MAYER, Scott C, CARRICK, Tikva, KRAMER, Angela, KOWAL, Dianne, LOCK, Tim, MARQUIS, Karen L, PAUSCH, Mark H, POPIOLEK, Mike, SUN, Shaiu-Ching

“…In functional assay assessments using the five muscarinic receptor subtypes, a second generation of muscarinic M(1)-preferring receptor agonists [AC-42 (1),…”
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Successful management of an MRSA outbreak in a neonatal intensive care unit by Heinrich, N., Mueller, A., Bartmann, P., Simon, A., Bierbaum, G., Engelhart, S.

“…We report an MRSA outbreak in our 25-bed tertiary neonatal intensive care unit (NICU), which was successfully contained. Methods include a retrospective review…”
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Methylphenidate and desipramine combined treatment improves PTSD symptomatology in a rat model by Aga-Mizrachi, S, Cymerblit-Sabba, A, Gurman, O, Balan, A, Shwam, G, Deshe, R, Miller, L, Gorodetsky, N, Heinrich, N, Tzezana, O, Zubedat, S, Grinstein, D, Avital, A

“…Antidepressant medication constitutes the first line pharmacological treatment for posttraumatic stress disorder (PTSD), however, because many patients display…”
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Optimising molecular diagnostic capacity for effective control of tuberculosis in high-burden settings by Sabiiti, W., Mtafya, B., Kuchaka, D., Azam, K., Viegas, S., Mdolo, A., Farmer, E. C. W., Khonga, M., Evangelopoulos, D., Honeyborne, I., Rachow, A., Heinrich, N., Ntinginya, N. E., Bhatt, N., Davies, G. R., Jani, I. V., McHugh, T. D., Kibiki, G., Hoelscher, M., Gillespie, S. H., on behalf of the PANBIOME (Pan-African Biomarker Expansion Programme) consortium

“…The World Health Organization's 2035 vision is to reduce tuberculosis (TB) associated mortality by 95%. While low-burden, well-equipped industrialised…”
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Performance of the Xpert® MTB/RIF assay in an active case-finding strategy: a pilot study from Tanzania [Short communication] by Ntinginya, E. N., Squire, S. B., Millington, K. A., Mtafya, B., Saathoff, E., Heinrich, N., Rojas-Ponce, G., Kowuor, D., Maboko, L., Reither, K., Clowes, P., Hoelscher, M., Rachow, A.

“…In this pilot study, we evaluated the Xpert® MTB/RIF assay in an active case-finding strategy, using two spot sputum samples collected within a 1-hour interval…”
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Comparison of odour emission rates measured from various sources using two sampling devices by Hudson, N., Ayoko, G.A., Dunlop, M., Duperouzel, D., Burrell, D., Bell, K., Gallagher, E., Nicholas, P., Heinrich, N.

“…Two commonly used sampling devices (a wind tunnel and the US EPA dynamic emission chamber), were used to collect paired samples of odorous air from a number of…”
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Evidence that corticotropin‐releasing factor receptor type 1 couples to Gs‐ and Gi‐proteins through different conformations of its J‐domain by Berger, H, Heinrich, N, Wietfeld, D, Bienert, M, Beyermann, M

“…Background and purpose: According to the two‐domain model for the corticotropin‐releasing factor receptor type 1 (CRF1), peptide antagonists bind to the…”
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Characterization of new estrogen receptor destabilizing compounds: Effects on estrogen-sensitive and tamoxifen-resistant breast cancer by HOFFMANN, Jens, BOHLMANN, Rolf, GIESCHEN, Hille, ULBRICH, Hannes-F, SCHNEIDER, Martin R, HEINRICH, Nikolaus, HOFMEISTER, Helmut, KROLL, Jörg, KÜNZER, Hermann, LICHTNER, Rosemarie B, NISHINO, Yuki, PARCZYK, Karsten, SAUER, Gerhard

“…Antiestrogens of the selective estrogen receptor modulator (SERM) type, such as tamoxifen, have two major limitations: their mixed agonist and antagonist…”
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Pharmacology and clinical use of sex steroid hormone receptor modulators by Cleve, A, Fritzemeier, K-H, Haendler, B, Heinrich, N, Möller, C, Schwede, W, Wintermantel, T

“…Sex steroid receptors are ligand-triggered transcription factors. Oestrogen, progesterone and androgen receptors form, together with the glucocorticoid and…”
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A continuously monitored colorimetric method for detection of Mycobacterium tuberculosis complex in sputum by Rojas-Ponce, G., Rachow, A., Guerra, H., Mapamba, D., Joseph, J., Mlundi, R., Marimoto, S., Ntinginya, N. E., Mangu, C., Framhein, A., Butler, A., Kohlenberg, A., Ngatemelela, D., Froeschl, G., Maboko, L., Hoelscher, M., Heinrich, N.

“…SETTING: Mbeya, Tanzania.OBJECTIVE: To develop a new liquid culture method to detect Mycobacterium tuberculosis complex (MTC) in sputum using…”
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Achieving signalling selectivity of ligands for the corticotropin‐releasing factor type 1 receptor by modifying the agonist's signalling domain by Beyermann, M, Heinrich, N, Fechner, K, Furkert, J, Zhang, W, Kraetke, O, Bienert, M, Berger, H

“…Background and purpose: Most of the pharmaceuticals target G‐protein‐coupled receptors (GPCRs) which can generally activate different signalling events. The…”
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A case of disseminated tuberculosis with psoas abscess in a 12-year-old girl with sickle cell trait by Heinrich, N, Prusseit, J, Born, M, Fleischhack, G, Simon, A

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Prebiotic organic synthesis in early Earth and Mars atmospheres: Laboratory experiments with quantitative determination of products formed in a cold plasma flow reactor by Heinrich, Michael N., Khare, Bishun N., McKay, Christopher P.

“…The goal of this study was to explore prebiotic chemistry in a range of plausible early Earth and Mars atmospheres. To achieve this laboratory continuous flow…”
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Estimation of deoxynivalenol (DON) content by symptom rating and exoantigen content for resistance selection in wheat and triticale by MIEDANER, T, HEINRICH, N, SCHNEIDER, B, OETTLER, G, ROHDE, S, RABENSTEIN, F

“…Fusarium head blight (FHB) in wheat and triticale leads to contamination of the grain with the mycotoxin deoxynivalenol (DON) that is harmful to animal and…”
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