Search Results - "Heinrich, Klaus"
-
1
Inhibition of Human Tyrosinase Requires Molecular Motifs Distinctively Different from Mushroom Tyrosinase
Published in Journal of investigative dermatology (01-07-2018)“…Tyrosinase is the rate-limiting enzyme of melanin production and, accordingly, is the most prominent target for inhibiting hyperpigmentation. Numerous…”
Get full text
Journal Article -
2
Structure-Activity Relationships of Thiazolyl Resorcinols, Potent and Selective Inhibitors of Human Tyrosinase
Published in International journal of molecular sciences (28-02-2018)“…Tyrosinase inhibitors are of great clinical interest as agents for the treatment of hyperpigmentary disorders; however, most compounds described in the…”
Get full text
Journal Article -
3
Improvement of stability and enzymatic activity by site-directed mutagenesis of E. coli asparaginase II
Published in Biochimica et biophysica acta (01-07-2014)“…Bacterial asparaginases (EC 3.5.1.1) have attracted considerable attention because enzymes of this group are used in the therapy of certain forms of leukemia…”
Get full text
Journal Article -
4
Monitoring protein aggregation during thermal unfolding in circular dichroism experiments
Published in Protein science (01-03-2006)“…Thermal unfolding monitored by spectroscopy or calorimetry is widely used to determine protein stability. Equilibrium thermodynamic analysis of such unfolding…”
Get full text
Journal Article -
5
The thermal dependence of the protein‐sparing effect in rainbow trout (Oncorhynchus mykiss, Walbaum 1792)
Published in Journal of fish biology (01-07-2023)“…The authors performed an instantaneous bioenergetic study with rainbow trout (Oncorhynchus mykiss) of 206.3 g ± 2.9 g in a group respirometer of nine 250 l…”
Get full text
Journal Article -
6
Expression in non-melanogenic systems and purification of soluble variants of human tyrosinase
Published in Biological chemistry (01-05-2013)“…Mammalian tyrosinases are key enzymes of melanin formation. Their native forms undergo complex maturation and sorting processes before being integrated into…”
Get more information
Journal Article -
7
Evaluation of the grid convergence for a rocket combustion chamber with a porous injector
Published in Acta astronautica (01-05-2019)“…A study of the grid convergence was carried out in order to quantify the mesh impact on simulations of rocket combustion chambers performed using the averaged…”
Get full text
Journal Article -
8
Air Leakages at Microvalves: Pressure Decay Measurements and Extended Continuum Modelling of Knudsen Flows
Published in Micromachines (Basel) (16-10-2024)“…To improve the performance of valves in relation to the leakage rate, a comprehensive evaluation of the valve characteristics and behavior during pressure…”
Get full text
Journal Article -
9
Fullerenes and Soot Formation- New Pathways to Large Particles in Flames
Published in Angewandte Chemie International Edition (02-10-1998)“…For as long as man has known fire, he has also been aware of soot–but the fact that fullerenes can be formed in a flame has only been been known for eleven…”
Get full text
Journal Article -
10
Characterization of a Pseudomonas putida ABC transporter (AatJMQP) required for acidic amino acid uptake: biochemical properties and regulation by the Aau two-component system
Published in Microbiology (Society for General Microbiology) (01-03-2008)“…Philipps University, Institute of Physiological Chemistry, D-35043 Marburg, Germany Correspondence Klaus-Heinrich Röhm roehm{at}staff.uni-marburg.de We…”
Get full text
Journal Article -
11
Determination of DPPH Radical Oxidation Caused by Methanolic Extracts of Some Microalgal Species by Linear Regression Analysis of Spectrophotometric Measurements
Published in Sensors (Basel, Switzerland) (03-10-2007)“…The demonstrated modified spectrophotometric method makes use of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and its specific absorbance properties…”
Get full text
Journal Article -
12
Migrating curlews on schedule: departure and arrival patterns of a long-distance migrant depend on time and breeding location rather than on wind conditions
Published in Movement ecology (17-03-2021)“…Departure decisions in long-distance migratory bird species may depend on favourable weather conditions and beneficial resources at the destination location,…”
Get full text
Journal Article -
13
On the interpretation of tyrosinase inhibition kinetics
Published in Journal of enzyme inhibition and medicinal chemistry (01-02-2014)“…Abstract Tyrosinases (monophenol monooxygenases, EC 1.14.18.1) utilize a reaction mechanism that involves two intertwined catalytic cycles and at least three…”
Get more information
Journal Article -
14
TFA and EPA productivities of Nannochloropsis salina influenced by temperature and nitrate stimuli in turbidostatic controlled experiments
Published in Marine drugs (27-09-2010)“…The influence of different nitrate concentrations in combination with three cultivation temperatures on the total fatty acids (TFA) and eicosapentaenoic acid…”
Get full text
Journal Article -
15
The AauR-AauS Two-Component System Regulates Uptake and Metabolism of Acidic Amino Acids in Pseudomonas putida
Published in Applied and Environmental Microbiology (01-10-2006)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
16
Engineering the substrate specificity of Escherichia coli asparaginase II. Selective reduction of glutaminase activity by amino acid replacements at position 248
Published in Protein science (01-10-2000)“…The use of Escherichia coli asparaginase II as a drug for the treatment of acute lymphoblastic leukemia is complicated by the significant glutaminase side…”
Get full text
Journal Article -
17
N-acetylamino acid utilization by kidney aminoacylase-1
Published in Biochimie (01-05-2008)“…Mammalian aminoacylase-1 (Acy1) participates in the breakdown of N-acetylated amino acids during intracellular protein catabolism. Acy1 is most abundantly…”
Get full text
Journal Article -
18
Distribution analysis of hydrogenases in surface waters of marine and freshwater environments
Published in PloS one (05-11-2010)“…Surface waters of aquatic environments have been shown to both evolve and consume hydrogen and the ocean is estimated to be the principal natural source. In…”
Get full text
Journal Article -
19
A new subfamily of bacterial glutamate/aspartate receptors
Published in Biological chemistry (01-01-2008)“…The specificity of bacterial nutrient importers of the ATP-binding cassette (ABC) type depends on external receptor proteins that not only bind the solute to…”
Get more information
Journal Article -
20
Recommendations for antiresorptive therapy in postmenopausal patients with breast cancer: Marburg AIBL Guideline Evaluation Study (MAGES)
Published in Breast cancer research and treatment (01-06-2012)“…Postmenopausal women with hormone-receptor-positive breast cancer usually receive aromatase inhibitor (AI) therapy at some point in their disease management…”
Get full text
Journal Article