Search Results - "Heinicke, U"
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Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcoma
Published in Oncogene (14-07-2016)“…JNJ-26481585 is a second-generation histone deacetylase inhibitor with broad-range efficacy and improved pharmacodynamic properties. In the present study, we…”
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Journal Article -
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Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo
Published in Oncogenesis (New York, NY) (01-02-2015)“…We have previously described novel histone acetyltransferase (HAT) inhibitors that block neuroblastoma cell growth in vitro . Here we show that two selected…”
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Journal Article -
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Sixteen novel mutations in the Cu/Zn superoxide dismutase gene in amyotrophic lateral sclerosis: a decade of discoveries, defects and disputes
Published in Amyotrophic lateral sclerosis and other motor neuron disorders (01-06-2003)“…OBJECTIVE: Since the discovery of mutations in the gene encoding Cu/Zn superoxide dismutase (SOD1) ten years ago, testing for SOD1 gene mutations has become a…”
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Journal Article -
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Identification of CRTH2 as a New PPARγ-Target Gene in T Cells Suggested CRTH2 Dependent Conversion of Th2 Cells as Therapeutic Concept in COVID-19 Infection
Published in ImmunoTargets and therapy (01-11-2024)“…COVID-19 is a serious viral infection, which is often associated with a lethal outcome. Therefore, understanding mechanisms, which affect the immune response…”
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Journal Article -
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Panel: distributed simulation in industry - a real-world necessity or ivory tower fancy?
Published in 2007 Winter Simulation Conference (01-12-2007)“…Distributed simulation has a long history at the Winter Simulation Conference. Although successful in the military domain it appears, however, that the idea of…”
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Conference Proceeding -
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Distributed simulation in industry - a real-world necessity or ivory tower fancy?: panel
Published in Proceedings of the 39th conference on Winter simulation: 40 years! The best is yet to come (09-12-2007)“…Distributed simulation has a long history at the Winter Simulation Conference. Although successful in the military domain it appears, however, that the idea of…”
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Conference Proceeding -
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Eliminate bottlenecks with integrated analysis tools in eM-Plant
Published in 2000 Winter Simulation Conference Proceedings (Cat. No.00CH37165) (2000)“…To build a realistic simulation model is all very well; to add real value you must identify the major difficulties and generate better alternatives. Tecnomatix…”
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Conference Proceeding