Search Results - "Heineman, F W"

ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo by Samaha, F F, Heineman, F W, Ince, C, Fleming, J, Balaban, R S

“…Glibenclamide, a known selective inhibitor of ATP-sensitive potassium channels, was infused into the coronary vasculature of anesthetized dogs and of isolated…”
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Effects of afterload and heart rate on NAD(P)H redox state in the isolated rabbit heart by Heineman, F W, Balaban, R S

“…NAD(P)H redox state was monitored using surface fluorescence in isolated, normothermic, working rabbit hearts under conditions of limited substrate (glucose…”
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Effect of substrate on mitochondrial NADH, cytosolic redox state, and phosphorylated compounds in isolated hearts by Scholz, T D, Laughlin, M R, Balaban, R S, Kupriyanov, V V, Heineman, F W

“…The effect of metabolic substrates on the relation among cytosolic redox state (NADHc/NAD+) mitochondrial NADH (NADHm), and [ATP]/([ADP] x [Pi]) was studied in…”
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Control of mitochondrial respiration in the heart in vivo by HEINEMAN, F. W, BALABAN, R. S

“…After reviewing the controversies in the literature surrounding the regulation of oxidative phosphorylation, a unifying theory to integrate the disparate…”
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Magnetization transfer contrast in MR imaging of the heart by Balaban, R S, Chesnick, S, Hedges, K, Samaha, F, Heineman, F W

“…The use of magnetization transfer contrast (MTC) in short-echo-time (TE) cardiac magnetic resonance (MR) imaging was evaluated. For most cardiac MR imaging…”
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Transmural distribution of intramyocardial pressure measured by micropipette technique by Heineman, F W, Grayson, J

“…A technique is presented for measuring intramyocardial pressure (IMP) in beating hearts using the servo-nulling pressure transducer equipped with polyethylene…”
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Myocardial oxygenation in the isolated working rabbit heart as a function of work by Heineman, F W, Kupriyanov, V V, Marshall, R, Fralix, T A, Balaban, R S

“…Myocardial O2 consumption (MVO2) was stimulated up to two-fold by either increasing afterload or beta-receptor stimulation in working normothermic isolated…”
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Impairment of myocardial calcium homeostasis by antibodies against the adenine nucleotide translocator by Schulze, K., Heineman, F.W., Schultheiß, H.-P., Balaban, R.S.

“…The adenine nucleotide translocator (ANT) is an autoantigen in myocarditis and dilated cardiomyopathy. Carrier-specific antibodies impair myocardial energy…”
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Developmental changes in the relation between phosphate metabolites and oxygen consumption in the sheep heart in vivo by PORTMAN, M. A, HEINEMAN, F. W, BALABAN, R. S

“…This study examines the role of phosphate metabolites in the regulation of mitochondrial oxygen consumption of the heart in vivo as a function of development…”
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Effects of beta-hydroxybutyrate on oxidative metabolism and phosphorylation potential in canine heart in vivo by Kim, D K, Heineman, F W, Balaban, R S

“…beta-Hydroxy-butyrate (HBA) is an effective substrate for mitochondrial respiration (MVO2) in the heart. Myocardial HBA oxidation is associated with high…”
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NMR spectral analysis of kinetic data using natural lineshapes by Heineman, F W, Eng, J, Berkowitz, B A, Balaban, R S

“…An automated rapid data analysis scheme for NMR spectroscopy time course studies is presented. This method uses a high signal-to-noise reference spectrum…”
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Effect of work on intracellular calcium of the intact heart by Fralix, T A, Heineman, F W, Balaban, R S

“…Intracellular calcium has been proposed to play a key role in the orchestration of metabolic rate with contractile activity in the mammalian heart. Calcium is…”
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Simultaneous monitoring of coronary blood flow and 31P NMR detected myocardial metabolites by Portman, M A, James, S, Heineman, F W, Balaban, R S

“…We report a method of dynamically measuring coronary blood flow in lambs, while simultaneously monitoring cardiac phosphate metabolism with 31P NMR at 81 MHz…”
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Phosphorus-31 nuclear magnetic resonance analysis of transient changes of canine myocardial metabolism in vivo by Heineman, F W, Balaban, R S

“…The time course of the relative myocardial phosphocreatine and adenosine triphosphate contents (PCr/ATP) during step changes in heart rate in vivo was studied…”
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Regional and transmural myocardial temperature distribution in cold chemical cardioplegia: significance of critical coronary arterial stenosis by Heineman, F W, MacGregor, D C, Wilson, G J, Ninomiya, J

“…There is a growing recognition of discrepancies in myocardial temperatures during cold chemical cardioplegia. This study was designed to determine the extent…”
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The relationship between phosphorylation potential and redox state in the isolated working rabbit heart by Laughlin, M R, Heineman, F W

“…The effects of the cytosolic and mitochondrial redox state on the function and phosphorylation potential of working perfused rabbit hearts were studied. Hearts…”
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Control of mitochondrial respiration in the heart in vivo by Balaban, R S, Heineman, F W

“…The role of the hydrolysis products of adenosine triphosphate (ATP), adenosine diphosphate (ADP) and inorganic phosphate (Pi), in the control of myocardial…”
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Effects of tissue absorbance on NAD(P)H and Indo-1 fluorescence from perfused rabbit hearts by Fralix, Teresa A., Heineman, Frederick W., Balaban, Robert S.

“…The effects of tissue optical absorbance on intracellular NAD(P)H and Indo-1 fluorescence emission have been evaluated in the perfused rabbit heart. These…”
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Pshophorus-31 nuclear magnetic resonance analysis of transient changes of canine myocardial metabolism in vivo by HEINEMAN, F. W, BALABAN, R. S

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