Search Results - "Hein, Kerstin"

“Collateral beauty.” Experiences and needs of professionals caring for parents continuing pregnancy after a life-limiting prenatal diagnosis: A grounded theory study by Wiesner, Konstanze, Hein, Kerstin, Borasio, Gian Domenico, Führer, Monika

“…Background: Caring for parents continuing pregnancy after learning about a severe life-limiting condition in their unborn is challenging. Most existing studies…”
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Participatory Development of a Modular Advance Care Planning Program in Pediatric Palliative Care (MAPPS) by Knochel, Kathrin, Zaimovic, Vedrana, Gatzweiler, Birga, Hein, Kerstin K., Heitkamp, Nari, Monz, Anna, Reimann, Daniel, Borasio, Gian Domenico, Führer, Monika

“…Decision-making in pediatric palliative care concerns mainly children without decision-making capacity. It has to balance the child's best interests, parental…”
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Perinatal Palliative Care: A qualitative study evaluating the perspectives of pregnancy counselors by Flaig, Franziska, Lotz, Julia D, Knochel, Kathrin, Borasio, Gian Domenico, Führer, Monika, Hein, Kerstin

“…Background: A prenatal diagnosis of a life-limiting disease raises complex ethical, emotional, and medical issues. Studies suggest that 40%–85% of parents…”
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Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site by Yuan, Zhenyu, VanderWielen, Bradley D., Giaimo, Benedetto Daniele, Pan, Leiling, Collins, Courtney E., Turkiewicz, Aleksandra, Hein, Kerstin, Oswald, Franz, Borggrefe, Tilman, Kovall, Rhett A.

“…Notch is a conserved signaling pathway that is essential for metazoan development and homeostasis; dysregulated signaling underlies the pathophysiology of…”
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Two proteolytic modules are involved in regulated intramembrane proteolysis of Bacillus subtilis RsiW by Heinrich, Janine, Hein, Kerstin, Wiegert, Thomas

“…Stress-induced degradation of the Bacillus subtilis anti-sigma factor RsiW results in the induction of genes controlled by the extracytoplasmic function sigma…”
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The Path Is Made by Walking—Mapping the Healthcare Pathways of Parents Continuing Pregnancy after a Severe Life-Limiting Fetal Diagnosis: A Qualitative Interview Study by Hein, Kerstin, Flaig, Franziska, Schramm, Annika, Borasio, Gian Domenico, Führer, Monika

“…In Germany, research on experiences and care pathways of parents continuing pregnancy after a life-limiting fetal diagnosis is scarce. There are several…”
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A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes by Oswald, Franz, Rodriguez, Patrick, Giaimo, Benedetto Daniele, Antonello, Zeus A., Mira, Laura, Mittler, Gerhard, Thiel, Verena N., Collins, Kelly J., Tabaja, Nassif, Cizelsky, Wiebke, Rothe, Melanie, Kühl, Susanne J., Kühl, Michael, Ferrante, Francesca, Hein, Kerstin, Kovall, Rhett A., Dominguez, Maria, Borggrefe, Tilman

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Scaffolds for seeing, using, and articulating logical structures in proofs: Design research study with high school students by Hein, Kerstin, Prediger, Susanne

“…Logical structures count as critical learning content for learning to prove. They are often not sufficiently explicated, and students struggle to use and…”
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Wnt/β-Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells by Hoffmeyer, Katrin, Raggioli, Angelo, Rudloff, Stefan, Anton, Roman, Hierholzer, Andreas, Del Valle, Ignacio, Hein, Kerstin, Vogt, Riana, Kemler, Rolf

“…Telomerase activity controls telomere length and plays a pivotal role in stem cells, aging, and cancer. Here, we report a molecular link between Wnt/β-catenin…”
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Identifying key elements for paediatric advance care planning with parents, healthcare providers and stakeholders: A qualitative study by Hein, Kerstin, Knochel, Kathrin, Zaimovic, Vedrana, Reimann, Daniel, Monz, Anna, Heitkamp, Nari, Borasio, Gian Domenico, Führer, Monika

“…Background: Although international guidelines recommend discussions about goals of care and treatment options for children with severe and life-limiting…”
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Aproximación al análisis cualitativo de redes sociales. Experiencias en el estudio de redes personales mediante Ego.Net.QF by Hein, Kerstin, Cárdenas Tomažič, Ana, Henríquez, Karla, Valenzuela, Santiago

“…ResumenEl texto realiza una aproximación a la práctica de la investigación sobre redes sociales desde una perspectiva cualitativa. Dentro de este contexto…”
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How to Open the Door: A Qualitative, Observational Study on Initiating Advance Care Discussions with Parents in Pediatric Palliative Care by Daxer, Marion, Monz, Anna, Hein, Kerstin, Heitkamp, Nari, Knochel, Kathrin, Borasio, Gian Domenico, Führer, Monika

“…Advance care discussions (ACD) between health care professionals (HCPs) and parents of children with a life-limiting disease are a core element of successful…”
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Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response by Giaimo, Benedetto Daniele, Ferrante, Francesca, Vallejo, Diana M, Hein, Kerstin, Gutierrez-Perez, Irene, Nist, Andrea, Stiewe, Thorsten, Mittler, Gerhard, Herold, Susanne, Zimmermann, Tobias, Bartkuhn, Marek, Schwarz, Peggy, Oswald, Franz, Dominguez, Maria, Borggrefe, Tilman

“…Abstract A fundamental as yet incompletely understood feature of Notch signal transduction is a transcriptional shift from repression to activation that…”
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A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes by Oswald, Franz, Rodriguez, Patrick, Giaimo, Benedetto Daniele, Antonello, Zeus A, Mira, Laura, Mittler, Gerhard, Thiel, Verena N, Collins, Kelly J, Tabaja, Nassif, Cizelsky, Wiebke, Rothe, Melanie, Kühl, Susanne J, Kühl, Michael, Ferrante, Francesca, Hein, Kerstin, Kovall, Rhett A, Dominguez, Maria, Borggrefe, Tilman

“…The transcriptional shift from repression to activation of target genes is crucial for the fidelity of Notch responses through incompletely understood…”
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Perspectivas de juventud en el imaginario de la política pública by Hein, Kerstin, Cárdenas, Ana

“…El presente artículo da cuenta de algunos de los resultados obtenidos a partir de una investigación que tiene como objetivo central generar un marco conceptual…”
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Let My Child Decide: Qualitative Interview Study With Mothers and Fathers Continuing Pregnancy After a Severe Life-Limiting Diagnosis of their Unborn Child by Hein, Kerstin, Schramm, Annika, Flaig, Franziska, Rabenhorst, Dorothee, Borasio, Gian Domenico, Führer, Monika

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Challenges in Pediatric Advance Care Discussions Between Health Care Professionals and Parents of Children with a Life-Limiting Condition: A Qualitative Pilot Study by Hein, Kerstin, Monz, Anna, Daxer, Marion, Heitkamp, Nari, Knochel, Kathrin, Jox, Ralf, Borasio, Gian Domenico, Führer, Monika

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Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response by Hein, Kerstin, Mittler, Gerhard, Cizelsky, Wiebke, Kühl, Michael, Ferrante, Francesca, Liefke, Robert, Berger, Ina M, Just, Steffen, Sträng, J Eric, Kestler, Hans A, Oswald, Franz, Borggrefe, Tilman

“…Physiologically, Notch signal transduction plays a pivotal role in differentiation; pathologically, Notch signaling contributes to the development of cancer…”
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Recruitment and Baseline Characteristics of Participants in the AgeWell.de Study-A Pragmatic Cluster-Randomized Controlled Lifestyle Trial against Cognitive Decline by Röhr, Susanne, Zülke, Andrea, Luppa, Melanie, Brettschneider, Christian, Weißenborn, Marina, Kühne, Flora, Zöllinger, Isabel, Samos, Franziska-Antonia Zora, Bauer, Alexander, Döhring, Juliane, Krebs-Hein, Kerstin, Oey, Anke, Czock, David, Frese, Thomas, Gensichen, Jochen, Haefeli, Walter E, Hoffmann, Wolfgang, Kaduszkiewicz, Hanna, König, Hans-Helmut, Thyrian, Jochen René, Wiese, Birgitt, Riedel-Heller, Steffi G

“…Targeting dementia prevention, first trials addressing multiple modifiable risk factors showed promising results in at-risk populations. In Germany, AgeWell.de…”
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Production of HIV virus-like particles by transient transfection of CAP-T cells at bioreactor scale avoiding medium replacement by Gutiérrez-Granados, Sonia, Farràs, Queralt, Hein, Kerstin, Fuenmayor, Javier, Félez, Pablo, Segura, Mercedes, Gòdia, Francesc

“…•CAP-T cells were successfully cultured and transfected in 1 L bioreactor.•VLPs were obtained in bioreactor with the expected quantity and quality.•Medium…”
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