Search Results - "Heimer, EP"
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Dipeptidylpeptidase IV and trypsin-like enzymatic degradation of human growth hormone-releasing hormone in plasma
Published in The Journal of clinical investigation (01-05-1989)“…The plasma enzyme responsible for primary proteolytic cleavage of growth hormone-releasing hormone (GRH) at the 2-3 amino acid bond was characterized. Native…”
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2
Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites
Published in Nature (London) (16-07-1987)“…A 12 amino-acid synthetic peptide (NANP)3 comprising the immunodominant epitope of Plasmodium falciparum circumsporozoite protein was conjugated to tetanus…”
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3
Recent applications of enzymatic peptide synthesis
Published in Peptides (New York, N.Y. : 1980) (01-01-1994)“…Recent applications of enzyme catalysis in peptide synthesis are reviewed. A brief history of the development of these techniques is presented, and existing…”
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4
Processing protease and reverse transcriptase from human immunodeficiency virus type I polyprotein in Escherichia coli
Published in Journal of Virology (01-04-1988)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An 11-kDa Form of Human Immunodeficiency Virus Protease Expressed in Escherichia coli is Sufficient for Enzymatic Activity
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1988)“…In order to define the protease domain of human immunodeficiency virus 1, various regions of the pol open reading frame were cloned and expressed in…”
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6
Calcium-dependent smooth muscle excitatory effect elicited by the venom of the hydrocoral Millepora complanata
Published in Toxicon (Oxford) (01-06-2002)“…In the present paper, we describe the results obtained from a preliminary pharmacological and biochemical study of the fire coral Millepora complanata, a…”
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7
Assessment in humans of a synthetic peptide-based vaccine against the sporozoite stage of the human malaria parasite, Plasmodium falciparum
Published in The Journal of immunology (1950) (15-01-1988)“…Eleven volunteers were injected with an anti-malaria (Plasmodium falciparum) sporozoite vaccine candidate consisting of a synthetic peptide, Ac-Cys-(NANP)3,…”
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Immunoregulatory Activities of Human Immunodeficiency Virus (HIV) Proteins: Effect of HIV Recombinant and Synthetic Peptides on Immunoglobulin Synthesis and Proliferative Responses by Normal Lymphocytes
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1988)“…Recombinant and synthetic peptides corresponding to envelope proteins of the human immunodeficiency virus (HIV) were examined for their effects on the…”
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9
Kinetics of dipeptidyl peptidase IV proteolysis of growth hormone-releasing factor and analogs
Published in Biochimica et biophysica acta (31-07-1992)“…The kinetics and selectivity of proteolysis of synthetic human growth hormone-releasing factor and analogs by purified human placental dipeptidyl peptidase IV…”
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10
Effect of active immunization against growth hormone-releasing factor on growth and onset of puberty in beef heifers
Published in Journal of animal science (01-12-1991)“…Angus and Charolais heifers (195 +/- 7 kg) were actively immunized against growth hormone-releasing factor (GRF) to evaluate the effect on concentrations of…”
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11
Rapid removal of protecting groups from peptides by catalytic transfer hydrogenation with 1,4-cyclohexadiene
Published in Journal of organic chemistry (01-10-1978)Get full text
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12
GRF analogs and fragments: correlation between receptor binding, activity and structure
Published in Peptides (New York, N.Y. : 1980) (1991)“…GH-releasing activity in vitro was directly correlated with GRF receptor binding affinity for all hGRF analogs examined. hGRF(1-29)-NH2 analogs with…”
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13
Effect of feed restriction on serum somatotropin, insulin-like growth factor-I-(IGF-I) and IGF binding proteins in cyclic heifers actively immunized against growth hormone releasing factor
Published in Domestic animal endocrinology (01-10-1993)“…Feed restriction often increases serum somatotropin (ST) and decreases insulin-like growth factor-I (IGF-I) in ruminants; however, the mechanisms responsible…”
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14
Enzymatic semisynthesis of a superpotent analog of human growth hormone-releasing factor
Published in Journal of medicinal chemistry (16-10-1992)“…A superpotent analog of human growth hormone-releasing factor, [desNH2Tyr1,D-Ala2,Ala15]-GRF(1-29)-NH2 (4), was prepared from the precursor,…”
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15
Concentrations of hormones and metabolites, estimates of metabolism, performance, and reproductive performance of sows actively immunized against growth hormone-releasing factor
Published in Journal of animal science (01-06-1994)“…Cyclic females actively immunized against growth hormone-releasing factor (GRFi; n = 5) or human serum albumin (HSAi; n = 4) were used to determine the effects…”
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16
Synthesis, biological activity and conformational analysis of cyclic GRF analogs
Published in International journal of peptide and protein research (01-12-1988)“…A novel cyclic GRF analog, cyclo(Asp8-Lys12)-[Asp8,Ala15]-GRF(1-29)-NH2, i.e. cyclo8,12[Asp8,Ala15]-GRF(1-29)-NH2, was synthesized by the solid phase procedure…”
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17
Cellular distribution of prothymosin alpha and parathymosin in rat thymus and spleen
Published in The journal of histochemistry and cytochemistry (01-12-1990)“…By means of immunohistochemical methods, we have investigated the cellular distribution of prothymosin alpha and parathymosin in rat thymus and spleen, using…”
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18
Effect of daily replacement therapy with recombinant bovine somatotropin on somatotropin, insulin-like growth factor I, and onset of puberty in beef heifers immunized against growth hormone-releasing factor
Published in Journal of animal science (01-07-1994)“…Two experiments examined whether replacement therapy with recombinantly derived bovine somatotropin (rbST) would induce puberty in heifers that had been…”
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Feedlot performance, carcass characteristics, hormones, metabolites in steers actively immunized against growth hormone-releasing factor
Published in Journal of animal science (01-11-1993)“…Large-framed Simmental and Charolais steers were actively immunized against growth hormone-releasing factor (GRF) to evaluate the effect on growth, carcass…”
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Defining minimal requirements for antibody production to peptide antigens
Published in Vaccine (01-06-1990)“…The role that individual determinants play in modulating the immune response of an organism to a pathogen is often obscured because of the complexity of the…”
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