Search Results - "Heimark, L"

Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells by Vrba, Lukas, Jensen, Taylor J, Garbe, James C, Heimark, Ronald L, Cress, Anne E, Dickinson, Sally, Stampfer, Martha R, Futscher, Bernard W

“…The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal…”
Get full text

N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1 by ALEXANDER, Nelson R, TRAN, Nhan L, REKAPALLY, Harish, SUMMERS, Carol E, GLACKIN, Carlotta, HEIMARK, Ronald L

“…The gain of N-cadherin expression in carcinomas has been shown to be important in the regulation of cell migration, invasion, and survival. Here, we show that…”
Get full text

Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo by Cox, Christopher M., D'Agostino, Susan L., Miller, Melanie K., Heimark, Ronald L., Krieg, Paul A.

“…The peptide growth factor apelin is the high affinity ligand for the G-protein-coupled receptor APJ. During embryonic development of mouse and frog, APJ…”
Get full text

Transforming growth factor beta signaling in adult cardiovascular diseases and repair by Doetschman, Thomas, Barnett, Joey V, Runyan, Raymond B, Camenisch, Todd D, Heimark, Ronald L, Granzier, Henk L, Conway, Simon J, Azhar, Mohamad

“…The majority of children with congenital heart disease now live into adulthood due to the remarkable surgical and medical advances that have taken place over…”
Get full text

Clear cell renal cell carcinoma molecular variations in non‐Hispanic White and Hispanic patients by Batai, Ken, Chen, Yuliang, Rheinheimer, Brenna A., Arora, Amit, Pandey, Ritu, Heimark, Ronald L., Bracamonte, Erika R., Ellis, Nathan A., Lee, Benjamin R.

“…Background The United States is becoming increasingly diverse, but few molecular studies have assessed the progression of clear cell renal cell carcinoma…”
Get full text

Hedgehog signaling is essential for endothelial tube formation during vasculogenesis by Vokes, Steven A, Yatskievych, Tatiana A, Heimark, Ronald L, McMahon, Jill, McMahon, Andrew P, Antin, Parker B, Krieg, Paul A

“…During embryonic development, the first blood vessels are formed through the aggregation and subsequent assembly of angioblasts (endothelial precursors) into a…”
Get full text

MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers by Chandramouli, Anupama, Onyeagucha, Benjamin Chidi, Mercado-Pimentel, Melania E., Stankova, Lenka, Shahin, Nisreen Abu, LaFleur, Bonnie J., Heimark, Ronald L., Bhattacharyya, Achyut K., Nelson, Mark A.

“…Purpose: Expression of the PGE2 receptor, EP4, is up-regulated during colorectal carcinogenesis. However the mechanism leading to deregulation of the EP4…”
Get full text

Detachment of captured cancer cells under flow acceleration in a bio-functionalized microchannel by Cheung, Luthur Siu Lun, Zheng, Xiangjun, Stopa, Ashley, Baygents, James C, Guzman, Roberto, Schroeder, Joyce A, Heimark, Ronald L, Zohar, Yitshak

“…Attachment, deformation and detachment of N-cadherin expressing prostate and breast cancer cell lines in a functionalized microchannel under hydrodynamic…”
Get more information

Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization by Tran, Nhan L, Adams, Deanna G, Vaillancourt, Richard R, Heimark, Ronald L

“…Associated with the metastatic progression of epithelial tumors is the dynamic regulation of cadherins. Whereas E-cadherin is expressed in most epithelium and…”
Get full text

Developmental mechanisms underlying pathology of arteries by Schwartz, S M, Heimark, R L, Majesky, M W

“…This review tries to provide a general, and very speculative, view of growth control mechanisms that may be common to the development of blood vessels and to…”
Get more information

Kinematics of Specifically Captured Circulating Tumor Cells in Bio-Functionalized Microchannels by Cheung, L S, Xiangjun Zheng, Lian Wang, Guzman, R, Schroeder, J A, Heimark, R L, Baygents, J C, Zohar, Y

“…The attachment kinematics of cancer cells under hydrodynamic loading in antibody-functionalized microchannels has been studied…”
Get full text

N-cadherin expression in human prostate carcinoma cell lines: An epithelial-mesenchymal Transformation mediating adhesion with stromal cells by Tran, Nhan L, Nagle, Raymond B, Cress, Anne E, Heimark, Ronald L

“…In human prostate adenocarcinoma, an association between loss of E-cadherin, increased Gleason score, and extracapsular dissemination has been observed…”
Get full text

Low melting point agarose as a protection layer in photolithographic patterning of aligned binary proteins by Lee, Lap Man, Heimark, Ronald L, Guzman, Roberto, Baygents, James C, Zohar, Yitshak

“…A novel photolithography method to build aligned patterns of two different proteins is presented. Chessboard patterns of 125 microm x 125 microm squares are…”
Get more information

Cadherin-5 redistribution at sites of TNF-alpha and IFN-gamma-induced permeability in mesenteric venules by Wong, R K, Baldwin, A L, Heimark, R L

“…The response of the endothelial permeability barrier in microvascular networks of the rat mesentery to perfused immune inflammatory cytokines tumor necrosis…”
Get full text

Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II by Derbyshire, Zachary E, Halfter, Ursula M, Heimark, Ronald L, Sy, Terence H, Vaillancourt, Richard R

“…Although it is known that MEKK4 regulates MKK6, and p38 MAP kinase, extracellular stimuli that activate the serine/threonine kinase, MEKK4, are unknown. The…”
Get full text

Protocadherins: a large family of cadherin‐related molecules in central nervous system by Sano, K., Tanihara, H., Heimark, R.L., Obata, S., Davidson, M., St John, T., Taketani, S., Suzuki, S.

“…Using the polymerase chain reaction, we have isolated numerous rat and human cDNAs of which the deduced amino acid sequences are highly homologous to the…”
Get full text

Vein adaptation to arterialization in an experimental model by Westerband, Alex, Crouse, Dana, Richter, Lynne C., Aguirre, Maria L., Wixon, Christopher C., James, Donovan C., Mills, Joseph L., Hunter, Glenn C., Heimark, Ronald L.

“…Purpose: The events preceding myointimal thickening in vein grafts after vascular reconstructions are not well characterized. Indeed, the injury response…”
Get full text

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets by Heimark, Ronald L., Twardzik, Daniel R., Schwartz, Stephen M.

“…Damage to the vessel wall is a signal for endothelial migration and replication and for platelet release at the site of injury. Addition of transforming growth…”
Get full text

Human Schlemm's canal cells express the endothelial adherens proteins, VE-cadherin and PECAM-1 by Heimark, Ronald L., Kaochar, Salma, Stamer, W. Daniel

“…Purpose. The majority of resistance to outflow of aqueous humor resides at or near the inner wall of Schlemm's canal (SC). Transmembrane proteins that…”
Get full text

Integrin- and Cadherin-Mediated Induction of the Matrix Metalloprotease Matrilysin in Cocultures of Malignant Oral Squamous Cell Carcinoma Cells and Dermal Fibroblasts by Bair, Elisabeth L., Massey, Chad P., Tran, Nhan L., Borchers, Alexander H., Heimark, Ronald L., Cress, Anne E., Bowden, G.Tim

“…Matrilysin is a matrix metalloprotease (MMP) overexpressed in a number of cancers including skin, head and neck squamous cell carcinomas, and prostate and…”
Get full text