Search Results - "Heim, Lisanne"

Enhanced Acid Sphingomyelinase Activity Drives Immune Evasion and Tumor Growth in Non-Small Cell Lung Carcinoma by Kachler, Katerina, Bailer, Maximilian, Heim, Lisanne, Schumacher, Fabian, Reichel, Martin, Holzinger, Corinna D, Trump, Sonja, Mittler, Susanne, Monti, Juliana, Trufa, Denis I, Rieker, Ralf J, Hartmann, Arndt, Sirbu, Horia, Kleuser, Burkhard, Kornhuber, Johannes, Finotto, Susetta

“…The lipid hydrolase enzyme acid sphingomyelinase (ASM) is required for the conversion of the lipid cell membrane component sphingomyelin into ceramide. In…”
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NFATc1 Promotes Antitumoral Effector Functions and Memory CD8 + T-cell Differentiation during Non-Small Cell Lung Cancer Development by Heim, Lisanne, Friedrich, Juliane, Engelhardt, Marina, Trufa, Denis I, Geppert, Carol I, Rieker, Ralf J, Sirbu, Horia, Finotto, Susetta

“…Nuclear factor of activated T cells 1 (NFATc1) is a transcription factor activated by T-cell receptor (TCR) and Ca signaling that affects T-cell activation and…”
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Increased expression of the immunosuppressive interleukin-35 in patients with non-small cell lung cancer by Heim, Lisanne, Kachler, Katerina, Siegmund, Raphaela, Trufa, Denis I., Mittler, Susanne, Geppert, Carol-Immanuel, Friedrich, Juliane, Rieker, Ralf J., Sirbu, Horia, Finotto, Susetta

“…Background The immunosuppressive role of the cytokine IL-35 in patients with non-small cell lung cancer (NSCLC) is poorly understood. In this study, we…”
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IL-9 Producing Tumor-Infiltrating Lymphocytes and Treg Subsets Drive Immune Escape of Tumor Cells in Non-Small Cell Lung Cancer by Heim, Lisanne, Yang, Zuqin, Tausche, Patrick, Hohenberger, Katja, Chiriac, Mircea T, Koelle, Julia, Geppert, Carol-Immanuel, Kachler, Katerina, Miksch, Sarah, Graser, Anna, Friedrich, Juliane, Kharwadkar, Rakshin, Rieker, Ralf J, Trufa, Denis I, Sirbu, Horia, Neurath, Markus F, Kaplan, Mark H, Finotto, Susetta

“…Although lung cancer is the leading cause of cancer deaths worldwide, the mechanisms how lung cancer cells evade the immune system remain incompletely…”
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ID: 175: The role of STAT3 (Signal Transducer and Activator of Transcription protein-3) in non-small cell lung cancer (NSCLC) by Heim, Lisanne, Finotto, Susetta

“…STAT3 is a transcription factor that is activated downstream of several cytokines and growth factors by phosphorylation. It regulates the expression of genes…”
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ID: 175 by Heim, Lisanne, Finotto, Susetta

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Interleukin-10-regulated tumour tolerance in non-small cell lung cancer by Vahl, Julius Malte, Friedrich, Juliane, Mittler, Susanne, Trump, Sonja, Heim, Lisanne, Kachler, Katerina, Balabko, Liubov, Fuhrich, Nicole, Geppert, Carol-Immanuel, Trufa, Denis Iulian, Sopel, Nina, Rieker, Ralf, Sirbu, Horia, Finotto, Susetta

“…Background: Lung cancer is the most life-threatening cancer type worldwide. Treatment options include surgery, radio- and chemotherapy, as well as the use of…”
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The role of STAT3 (signal transducer and activator of transcription 3) in non-small cell lung cancer (NSCLC) by Heim, Lisanne, Andreev, Katerina, Balabko, Ljubov, Trufa, Denis Iulian, Sirbu, Horia, Hartmann, Arndt, Finotto, Susetta

“…Non-small cell lung cancer (NSCLC) is associated with high mortality worldwide underlining the need for novel therapeutic approaches. Signal transducer and…”
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The role of Signal Transducer and Activator of Transcription protein 5 (STAT5) in non-small cell lung cancer (NSCLC) by Friedrich, Juliane Michaela Margarete M, Heim, Lisanne, Springel, Rebekka, Mittler, Susanne, Gafencu, Dumitrita, Hartmann, Arndt, Sirbu, Horia, Finotto, Susetta

“…Signal Transducer and Activator of Transcription protein 5 (STAT5a/b) belongs to a family of T cell transcription factors. The different isoforms of STAT5 are…”
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STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFα mediated immune responses in a model of NSCLC by Friedrich, Juliane, Heim, Lisanne, Trufa, Denis I, Sirbu, Horia, Rieker, Ralf J, Chiriac, Mircea T, Finotto, Susetta

“…In this study we described that Signal Transducer and Activator of Transcription 1 (STAT1) is a key point regulator of PD-1 in tumour infiltrating lymphocytes…”
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FAM13A is associated with non-small cell lung cancer (NSCLC) progression and controls tumor cell proliferation and survival by Eisenhut, Felix, Heim, Lisanne, Trump, Sonja, Mittler, Susanne, Sopel, Nina, Andreev, Katerina, Ferrazzi, Fulvia, Ekici, Arif B., Rieker, Ralf, Springel, Rebekka, Assmann, Vera L., Lechmann, Matthias, Koch, Sonja, Engelhardt, Marina, Warnecke, Christina, Trufa, Denis I., Sirbu, Horia, Hartmann, Arndt, Finotto, Susetta

“…Genome-wide association studies (GWAS) associated Family with sequence similarity 13, member A (FAM13A) with non-small cell lung cancer (NSCLC) occurrence…”
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