Search Results - "Heils, A."

Early experience and serotonin transporter gene variation interact to influence primate CNS function by Bennett, A J, Lesch, K P, Heils, A, Long, J C, Lorenz, J G, Shoaf, S E, Champoux, M, Suomi, S J, Linnoila, M V, Higley, J D

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Early experience and serotonin transporter gene variation interact to influence primate CNS function by BENNETT, A. J, LESCH, K. P, HEILS, A, LONG, J. C, LORENZ, J. G, SHOAF, S. E, CHAMPOUX, M, SUOMI, S. J, LINNOILA, M. V, HIGLEY, J. D

“…Nonhuman primates offer unique opportunities to study the effects of genes, environments, and their interaction, on physiology and complex behavior. We…”
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Glucocorticoid‐regulated human serotonin transporter (5‐HTT) expression is modulated by the 5‐HTT gene‐promotor‐linked polymorphic region by Glatz, K., Mössner, R., Heils, A., Lesch, K. P.

“…Mood, emotion and cognition are modulated by serotonergic neurotransmission, while the physiological function of serotonergic synapses depends on serotonin…”
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Reduction in the Density and Expression, But Not G-Protein Coupling, of Serotonin Receptors (5-HT1A) in 5-HT Transporter Knock-Out Mice: Gender and Brain Region Differences by Li, Qian, Wichems, Christine, Heils, Armin, Lesch, Klaus-Peter, Murphy, Dennis L

“…The aim of the present study was to investigate the mechanisms underlying the desensitization of 5-HT(1A) receptors in the dorsal raphe and hypothalamus of…”
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A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders by Collier, D A, Stöber, G, Li, T, Heils, A, Catalano, M, Di Bella, D, Arranz, M J, Murray, R M, Vallada, H P, Bengel, D, Müller, C R, Roberts, G W, Smeraldi, E, Kirov, G, Sham, P, Lesch, K P

“…The serotonin transporter (5-HTT) is a candidate locus for aetiological involvement in affective disorders. Biochemical studies in suicides and depressed…”
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A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter by SPURLOCK, G, HEILS, A, LESCH, K. P, OWEN, M. J, HOLMANS, P, WILLIAMS, J, D'SOUZA, U. M, CARDNO, A, MURPHY, K. C, JONES, L, BUCKLAND, P. R, MCGUFFIN, P

“…Several studies have shown an association between schizophrenia and the C allele of a T-C polymorphism at nucleotide 102 and the 5HT2A receptor gene. In the…”
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Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder by BENGEL, D, GREENBERG, B. D, CORA-LOCATELLI, G, ALTEMUS, M, HEILS, A, LI, Q, MURPHY, D. L

“…Although modulation of symptoms of obsessive-compulsive disorder (OCD) by serotonergic agents is well established, it is unclear whether an abnormality in the…”
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The human serotonin transporter gene polymorphism--basic research and clinical implications by Heils, A, Mössner, R, Lesch, K P

“…Mood, emotion, and cognition are modulated by the serotonergic midbrain raphe system, which seems to be involved in the pathogenesis of psychiatric disorders…”
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The 5-HT transporter gene-linked polymorphic region (5-HTTLPR) in evolutionary perspective : alternative biallelic variation in rhesus monkeys by LESCH, K. P, MEYER, J, MÖSSNER, R, RIEDERER, P, HEILS, A, GLATZ, K, FLÜGGE, G, HINNEY, A, HEBEBRAND, J, KLAUCK, S. M, POUSTKA, A, POUSTKA, F, BENGEL, D

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Supportive evidence for an allelic association of the human KCNJ10 potassium channel gene with idiopathic generalized epilepsy by Lenzen, K.P., Heils, A., Lorenz, S., Hempelmann, A., Höfels, S., Lohoff, F.W., Schmitz, B., Sander, T.

“…Quantitative trait loci (QTL) mapping in mice revealed a seizure-related QTL ( Szs1), for which the inward-rectifying potassium channel Kcnj10 is the most…”
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Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene by HEILS, A, TEUFEL, A, PETRI, S, SEEMANN, M, BENGEL, D, BALLING, U, RIEDERER, P, LESCH, K.-P

“…We have isolated and characterized the 5'-flanking region and the proximal polyadenylation site of the human 5-HT transporter gene. The major gene transcript…”
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Obsessive compulsive disorder, response to serotonin reuptake inhibitors and the serotonin transporter gene by Billett, E A, Richter, M A, King, N, Heils, A, Lesch, K P, Kennedy, J L

“…Obsessive compulsive disorder (OCD) is a common illness, characterized by anxiety-provoking thoughts and the need to perform rituals. OCD is most commonly…”
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Serotonin transporter gene-linked polymorphic region: Allele distributions in relationship to body weight and in anorexia nervosa by Hinney, A., Barth, N., Ziegler, A., Von Prittwitz, S., Hamann, A., Hennighausen, K., Pirke, K.M., Heils, A., Rosenkranz, K., Roth, H., Coners, H., Mayer, H., Herzog, W., Siegfried, A., Lehmkuhl, G., Poustka, F., Schmidt, M.H., Schäfer, H., Grzeschik, K.-H., Lesch, K.-P., Lentes, K.-U., Remschmidt, H., Hebebrand, J.

“…Several lines of evidence implicate a role for the serotonergic system in body weight regulation and eating disorders. The magnitude and duration of…”
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Serotonin transporter gene polymorphism and affective disorder by Kunugi, H, Tatsumi, M, Sakai, T, Hattori, M, Nanko, S

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Functional promoter polymorphism of the human serotonin transporter: lack of association with panic disorder by Deckert, J, Catalano, M, Heils, A, Di Bella, D, Friess, F, Politi, E, Franke, P, Nöthen, M M, Maier, W, Bellodi, L, Lesch, K P

“…To probe the hypothesis of a role for a functionally relevant 44 bp insertion/deletion of the serotonin transporter promoter in the aetiopathogenesis of panic…”
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Insertion/deletion variant (-141C Ins/Del) in the 5' regulatory region of the dopamine D2 receptor gene : lack of association with schizophrenia and bipolar affective disorder by STÖBER, G, JATZKE, S, HEILS, A, JUNGKUNZ, G, KNAPP, M, MÖSSNER, R, RIEDERER, P, LESCH, K. P

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Isolated absence of the septum pellucidum by SUPPRIAN, T, SIAN, J, HEILS, A, HOFMANN, E, WARMUTH-METZ, M, SOLYMOSI, L

“…Absence of the septum pellucidum in the human is a rare congenital anomaly. Previous reports suggest it is almost always associated with other brain anomalies…”
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The role of neurotransporters in excitotoxicity, neuronal cell death, and other neurodegenerative processes by LESCH, K. P, HEILS, A, RIEDERER, P

“…Neurotransporters are high-affinity transport proteins located in the plasma membrane of both presynaptic nerve and glial cells that mediate the removal of…”
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Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy by Haug, K, Kremerskothen, J, Hallmann, K, Sander, T, Dullinger, J, Rau, B, Beyenburg, S, Lentze, M.J, Barnekow, A, Elger, C.E, Propping, P, Heils, A

“…Idiopathic generalized epilepsy (IGE) comprises a heterogeneous group of disorders, in which a high genetic predisposition and a complex mode of inheritance…”
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Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies by Alekov, Alexi K, Rau, Birgit, Hebeisen, Simon, Propping, Peter, Haverkamp, Fritz, Janz, Dieter, Fahlke, Christoph, Maljevic, Snezana, Beyenburg, Stefan, Haug, Karsten, Dullinger, Joern S, Kubisch, Christian, Lerche, Holger, Elger, Christian E, Ramírez, Alfredo, Horvath, Steve, Müller-Newen, Gerhard, Rebstock, Johannes, Heils, Armin, Warnstedt, Maike, Hallmann, Kerstin, Poser, Barbara, Giese, Bernd, Sander, Thomas, Schulz, Herbert

“…Idiopathic generalized epilepsy (IGE) is an inherited neurological disorder affecting about 0.4% of the world's population. Mutations in ten genes causing…”
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