Search Results - "Heilmann, Melanie"

Comparison of Digital Subtraction Angiography, Micro-Computed Tomography Angiography and Magnetic Resonance Angiography in the Assessment of the Cerebrovascular System in Live Mice by Figueiredo, Giovanna, Brockmann, Carolin, Boll, Hanne, Heilmann, Melanie, Schambach, Sebastian J., Fiebig, Teresa, Kramer, Martin, Groden, Christoph, Brockmann, Marc A.

“…Purpose Mice are often used as small animal models of brain ischemia, venous thrombosis, or vasospasm. This article aimed at providing an overview of the…”
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Simple models improve the discrimination of prostate cancers from the peripheral gland by T1-weighted dynamic MRI by Kiessling, Fabian, Lichy, Matthias, Grobholz, Rainer, Heilmann, Melanie, Farhan, Nabeel, Michel, Maurice Stephan, Trojan, Lutz, Ederle, Joerg, Abel, Ulrich, Kauczor, Hans-Ulrich, Semmler, Wolfhard, Delorme, Stefan

“…Evaluation of the accuracy of descriptive and physiological parameters calculated from signal intensity-time curves using T1-weighted dynamic contrast enhanced…”
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Dynamic Contrast-Enhanced Magnetic Resonance Imaging Rapidly Indicates Vessel Regression in Human Squamous Cell Carcinomas Grown in Nude Mice Caused by VEGF Receptor 2 Blockade with DC101 by Kiessling, Fabian, Farhan, Nabeel, Lichy, Matthias P., Vosseler, Silvia, Heilmann, Melanie, Krix, Martin, Bohlen, Peter, Miller, Dan W., Mueller, Margareta M., Semmler, Wolfhard, Fusenig, Norbert E., Delorme, Stefan

“…The purpose of our study was the investigation of early changes in tumor vascularization during antiangiogenic therapy with the vascular endothelial growth…”
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Dynamic Magnetic Resonance Tomography and Proton Magnetic Resonance Spectroscopy of Prostate Cancers in Rats Treated by Radiotherapy by Kiessling, Fabian, Huber, Peter E, Grobholz, Rainer, Heilmann, Melanie, Meding, Jörg, Lichy, Matthias P, Fink, Christian, Krix, Martin, Peschke, Peter, Schlemmer, Heinz-Peter

“…RATIONALE AND OBJECTIVESTo establish an experimental setting for monitoring perfusion and metabolism in orthotopic prostate cancer at 1.5 T using dynamic…”
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T 2 ‐relaxivity contrast imaging: First results by Sourbron, Steven, Heilmann, Melanie, Walczak, Christine, Vautier, Julien, Schad, Lothar R., Volk, Andreas

“…Abstract In this study, T 2 *‐ relaxivity contrast imaging (RCI) is proposed for new contrast generation in MRI. The method produces images of relaxivities r *…”
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T2-relaxivity contrast imaging: First results by Sourbron, Steven, Heilmann, Melanie, Walczak, Christine, Vautier, Julien, Schad, Lothar R., Volk, Andreas

“…In this study, T2*‐ relaxivity contrast imaging (RCI) is proposed for new contrast generation in MRI. The method produces images of relaxivities r*2,vasc and…”
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Quantification of glomerular number and size distribution in normal rat kidneys using magnetic resonance imaging by HEILMANN, Melanie, NEUDECKER, Sabine, WOLF, Ivo, GUBHAJU, Lina, STICHT, Carsten, SCHOCK-KUSCH, Daniel, KRIZ, Wilhelm, BERTRAM, John F, SCHAD, Lothar R, GRETZ, Norbert

“…Glomerular number and size are important risk factors for chronic kidney disease (CKD) and cardiovascular disease and have traditionally been estimated using…”
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T sub(2)-relaxivity contrast imaging: First results by Sourbron, Steven, Heilmann, Melanie, Walczak, Christine, Vautier, Julien, Schad, Lothar R, Volk, Andreas

“…In this study, T sub(2)*- relaxivity contrast imaging (RCI) is proposed for new contrast generation in MRI. The method produces images of relaxivities r*…”
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2D and 3D radial multi-gradient-echo DCE MRI in murine tumor models with dynamic R2-corrected R1 mapping by Vautier, Julien, Heilmann, Melanie, Walczak, Christine, Mispelter, Joël, Volk, Andreas

“…Dynamic contrast‐enhanced MRI is extensively studied to define and evaluate biomarkers for early assessment of vasculature‐targeting therapies. In this study,…”
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2D and 3D radial multi‐gradient‐echo DCE MRI in murine tumor models with dynamic R 2 ‐corrected R 1 mapping by Vautier, Julien, Heilmann, Melanie, Walczak, Christine, Mispelter, Joël, Volk, Andreas

“…Abstract Dynamic contrast‐enhanced MRI is extensively studied to define and evaluate biomarkers for early assessment of vasculature‐targeting therapies. In…”
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Characterization of a chip-based bioreactor for three-dimensional cell cultivation via Magnetic Resonance Imaging by Gottwald, Eric, Kleintschek, Tanja, Giselbrecht, Stefan, Truckenmüller, Roman, Altmann, Brigitte, Worgull, Matthias, Döpfert, Jörg, Schad, Lothar, Heilmann, Melanie

“…We describe the characterization of a chip-based platform (3D-KITChip) for the three-dimensional cultivation of cells under perfusion conditions via magnetic…”
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Determination of Pharmacokinetic Parameters in DCE MRI: Consequence of Nonlinearity Between Contrast Agent Concentration and Signal Intensity by Heilmann, Melanie, Kiessling, Fabian, Enderlin, Marta, Schad, Lothar R

“…OBJECTIVES:We sought to compare pharmacokinetic modeling of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data by assuming a linear and…”
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In vitro setup to study permeability characteristics of contrast agents by MRI by Heilmann, Melanie, Vautier, Julien, Robert, Philippe, Volk, Andreas

“…An experimental setup consisting of a hollow fiber module (HFM) was developed for the in vitro study of contrast agent (CA) permeability. Controllable flow and…”
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Simultaneous dynamic T 1 and T 2 measurement for AIF assessment combined with DCE MRI in a mouse tumor model by Heilmann, Melanie, Walczak, Christine, Vautier, Julien, Dimicoli, Jean-Luc, Thomas, Carole D., Lupu, Mihaela, Mispelter, Joël, Volk, Andreas

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Characterization and longitudinal monitoring of melanoma growth in ret-transgenic mice using a single-sequence MRI protocol by Kerl, Hans U., Boll, Hanne, Ramacher, Marcel, Heilmann, Melanie, Groden, Christoph, Kramer, Martin, Umansky, Viktor, Brockmann, Marc A.

“…Spontaneous melanoma models in transgenic mice are increasingly used in preclinical research as they most closely match the progression of melanoma in humans…”
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Evaluation of Chest Motion and Volumetry During the Breathing Cycle by Dynamic MRI in Healthy Subjects: Comparison With Pulmonary Function Tests by Plathow, Christian, Ley, Sebastian, Fink, Christian, Puderbach, Michael, Heilmann, Melanie, Zuna, Ivan, Kauczor, Hans-Ulrich

“…RATIONALE AND OBJECTIVES:To investigate diaphragm and chest wall motion during the whole breathing cycle using magnetic resonance imaging (MRI) and a…”
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Simultaneous dynamic T1 and T2 measurement for AIF assessment combined with DCE MRI in a mouse tumor model by Heilmann, Melanie, Walczak, Christine, Vautier, Julien, Dimicoli, Jean-Luc, Thomas, Carole D, Lupu, Mihaela, Mispelter, Joël, Volk, Andreas

“…A double-delay SR-MGE-SNAP sequence allowing simultaneous T1 and T2* measurement was developed for integrating arterial input function (AIF) measurement into…”
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Synthesis and Characterization of HE-24.8:  A Polymeric Contrast Agent for Magnetic Resonance Angiography by Kiessling, Fabian, Heilmann, Melanie, Lammers, Twan, Ulbrich, Karel, Subr, Vladimir, Peschke, Peter, Waengler, Bjoern, Mier, Walter, Schrenk, Hans-Herrmann, Bock, Michael, Schad, Lothar, Semmler, Wolfhard

“…The physical and biological properties of a water-soluble polymeric contrast agent based on a complex of N-(2-hydroxypropyl)methacrylamide copolymer with…”
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Susceptibility Weighted Imaging (SWI) of the kidney at 3 T – initial results by Mie, Moritz B., Nissen, Johanna C., Zöllner, Frank G., Heilmann, Melanie, Schoenberg, Stefan O., Michaely, Henrik J., Schad, Lothar R.

“…Susceptibility weighted imaging provides diagnostic information in strokes, hemorrhages, and cerebral tumors and has proven to be a valuable tool in imaging…”
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Comparing Dynamic Parameters of Tumor Vascularization in Nude Mice Revealed by Magnetic Resonance Imaging and Contrast-Enhanced Intermittent Power Doppler Sonography by Kiessling, Fabian, Krix, Martin, Heilmann, Melanie, Vosseler, Silvia, Lichy, Matthias, Fink, Christian, Farhan, Nabeel, Kleinschmidt, Katharina, Schad, Lothar, Fusenig, Norbert E, Delorme, Stefan

“…RATIONALEAngiogenesis is essential for spread and growth of malignant tumors. Because noninvasive methods for observing tumor vascularization are limited, most…”
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