Search Results - "Heilig, M."

Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms by Heilig, Markus, Egli, Mark

“…Alcoholism is a major public health problem and resembles, in many ways, other chronic relapsing medical conditions. At least 2 separate dimensions of its…”
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Does acute stress play a role in the lasting therapeutic effects of psychedelic drugs? by de Wit, H, Heilig, M, Bershad, A K

“…Psychedelic drugs, when used in the context of psychotherapy, can produce significant and long-lasting memories with enduring beneficial effects. Yet, the…”
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Comparisons of disparities and risks of HIV infection in black and other men who have sex with men in Canada, UK, and USA: a meta-analysis by Millett, Gregorio A, MPH, Peterson, John L, Prof, Flores, Stephen A, PhD, Hart, Trevor A, PhD, Jeffries, William L, PhD, Wilson, Patrick A, PhD, Rourke, Sean B, Prof, Heilig, Charles M, PhD, Elford, Jonathan, Prof, Fenton, Kevin A, MD, Remis, Robert S, Prof

“…Summary Background We did a meta-analysis to assess factors associated with disparities in HIV infection in black men who have sex with men (MSM) in Canada,…”
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A genetic determinant of the striatal dopamine response to alcohol in men by Ramchandani, V A, Umhau, J, Pavon, F J, Ruiz-Velasco, V, Margas, W, Sun, H, Damadzic, R, Eskay, R, Schoor, M, Thorsell, A, Schwandt, M L, Sommer, W H, George, D T, Parsons, L H, Herscovitch, P, Hommer, D, Heilig, M

“…Excessive alcohol use, a major cause of morbidity and mortality, is less well understood than other addictive disorders. Dopamine release in ventral striatum…”
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A comparison of machine learning algorithms for the surveillance of autism spectrum disorder by Lee, Scott H, Maenner, Matthew J, Heilig, Charles M

“…The Centers for Disease Control and Prevention (CDC) coordinates a labor-intensive process to measure the prevalence of autism spectrum disorder (ASD) among…”
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Seasonality of Tuberculosis in the United States, 1993—2008 by Willis, Matthew D., Winston, Carla A., Heilig, Charles M., Cain, Kevin P., Walter, Nicholas D., Mac Kenzie, William R.

“…Background. Although seasonal variation in tuberculosis incidence has been described in several recent studies, the mechanism underlying this seasonality…”
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Preclinical evaluation of the kappa-opioid receptor antagonist CERC-501 as a candidate therapeutic for alcohol use disorders by Domi, E, Barbier, E, Augier, E, Augier, G, Gehlert, D, Barchiesi, R, Thorsell, A, Holm, L, Heilig, M

“…Prior work suggests a role of kappa-opioid signaling in the control of alcohol drinking, in particular when drinking is escalated due to alcohol-induced…”
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Development of a standardized screening rule for tuberculosis in people living with HIV in resource-constrained settings: individual participant data meta-analysis of observational studies by Getahun, Haileyesus, Kittikraisak, Wanitchaya, Heilig, Charles M, Corbett, Elizabeth L, Ayles, Helen, Cain, Kevin P, Grant, Alison D, Churchyard, Gavin J, Kimerling, Michael, Shah, Sarita, Lawn, Stephen D, Wood, Robin, Maartens, Gary, Granich, Reuben, Date, Anand A, Varma, Jay K

“…The World Health Organization recommends the screening of all people living with HIV for tuberculosis (TB) disease, followed by TB treatment, or isoniazid…”
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Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model by Zallar, L. J., Tunstall, B. J., Richie, C. T., Zhang, Y. J., You, Z. B., Gardner, E. L., Heilig, M., Pickel, J., Koob, G. F., Vendruscolo, L. F., Harvey, B. K., Leggio, L.

“…Background/objectives Ghrelin, a stomach-derived hormone implicated in numerous behaviors including feeding, reward, stress, and addictive behaviors, acts by…”
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Dependence-induced increase of alcohol self-administration and compulsive drinking mediated by the histone methyltransferase PRDM2 by Barbier, E, Johnstone, A L, Khomtchouk, B B, Tapocik, J D, Pitcairn, C, Rehman, F, Augier, E, Borich, A, Schank, J R, Rienas, C A, Van Booven, D J, Sun, H, Nätt, D, Wahlestedt, C, Heilig, M

“…Epigenetic processes have been implicated in the pathophysiology of alcohol dependence, but the specific molecular mechanisms mediating dependence-induced…”
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Tuberculosis Caused by Mycobacterium africanum, United States, 2004-2013 by Sharma, Aditya, Bloss, Emily, Heilig, Charles M, Click, Eleanor S

“…Mycobacterium africanum is endemic to West Africa and causes tuberculosis (TB). We reviewed reported cases of TB in the United States during 2004-2013 that had…”
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Variation at the Rat Crhr1 Locus and Sensitivity to Relapse into Alcohol Seeking Induced by Environmental Stress by Hansson, A. C., Cippitelli, A., Sommer, W. H., Fedeli, A., Björk, K., Soverchia, L., Terasmaa, A., Massi, M., Heilig, M., Ciccocioppo, R.

“…Alcoholism is a chronic relapsing disorder with substantial heritability. Uncovering gene-environment interactions underlying this disease process can aid…”
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Buprenorphine and methadone treatment of opiate dependence during pregnancy: Comparison of fetal growth and neonatal outcomes in two consecutive case series by Kakko, Johan, Heilig, Markus, Sarman, Ihsan

“…Abstract Aim To compare the effects of fetal buprenorphine and methadone exposure during maintenance treatment of pregnant heroin dependent subjects. Design…”
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3D high throughput screening and profiling of embryoid bodies in thermoformed microwell plates by Vrij, E J, Espinoza, S, Heilig, M, Kolew, A, Schneider, M, van Blitterswijk, C A, Truckenmüller, R K, Rivron, N C

“…3D organoids using stem cells to study development and disease are now widespread. These models are powerful to mimic in vivo situations but are currently…”
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Measurement of the α-Particle Monopole Transition Form Factor Challenges Theory: A Low-Energy Puzzle for Nuclear Forces? by Kegel, S, Achenbach, P, Bacca, S, Barnea, N, Beričič, J, Bosnar, D, Correa, L, Distler, M O, Esser, A, Fonvieille, H, Friščić, I, Heilig, M, Herrmann, P, Hoek, M, Klag, P, Kolar, T, Leidemann, W, Merkel, H, Mihovilovič, M, Müller, J, Müller, U, Orlandini, G, Pochodzalla, J, Schlimme, B S, Schoth, M, Schulz, F, Sfienti, C, Širca, S, Spreckels, R, Stöttinger, Y, Thiel, M, Tyukin, A, Walcher, T, Weber, A

“…We perform a systematic study of the α-particle excitation from its ground state 0_{1}^{+} to the 0_{2}^{+} resonance. The so-called monopole transition form…”
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A relationship between the aldosterone–mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans by Aoun, E G, Jimenez, V A, Vendruscolo, L F, Walter, N A R, Barbier, E, Ferrulli, A, Haass-Koffler, C L, Darakjian, P, Lee, M R, Addolorato, G, Heilig, M, Hitzemann, R, Koob, G F, Grant, K A, Leggio, L

“…Aldosterone regulates electrolyte and fluid homeostasis through binding to the mineralocorticoid receptors (MRs). Previous work provides evidence for a role of…”
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Reduced cannabinoid CB1 receptor binding in alcohol dependence measured with positron emission tomography by Hirvonen, J, Zanotti-Fregonara, P, Umhau, J C, George, D T, Rallis-Frutos, D, Lyoo, C H, Li, C-T, Hines, C S, Sun, H, Terry, G E, Morse, C, Zoghbi, S S, Pike, V W, Innis, R B, Heilig, M

“…Brain cannabinoid CB 1 receptors contribute to alcohol-related behaviors in experimental animals, but their potential role in humans with alcohol dependence is…”
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Performance of Clinical Screening Algorithms for Tuberculosis Intensified Case Finding among People Living with HIV in Western Kenya by Modi, Surbhi, Cavanaugh, Joseph S, Shiraishi, Ray W, Alexander, Heather L, McCarthy, Kimberly D, Burmen, Barbara, Muttai, Hellen, Heilig, Chad M, Nakashima, Allyn K, Cain, Kevin P

“…To assess the performance of symptom-based screening for tuberculosis (TB), alone and with chest radiography among people living with HIV (PLHIV), including…”
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Substitution of Rifapentine for Rifampin During Intensive Phase Treatment of Pulmonary Tuberculosis: Study 29 of the Tuberculosis Trials Consortium by Dorman, Susan E., Goldberg, Stefan, Stout, Jason E., Muzanyi, Grace, Johnson, John L., Weiner, Marc, Bozeman, Lorna, Heilig, Charles M., Feng, Pei-Jean, Moro, Ruth, Narita, Masahiro, Nahid, Payam, Ray, Susan, Bates, Edward, Haile, Betial, Nuermberger, Eric L., Vernon, Andrew, Schluger, Neil W.

“…Background. Rifapentine administered 5 days per week has potent activity in mouse models of antituberculosis chemotherapy, but efficacy and safety data are…”
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Common roots: a contextual review of HIV epidemics in black men who have sex with men across the African diaspora by Millett, Gregorio A, MPH, Jeffries, William L, PhD, Peterson, John L, Prof, Malebranche, David J, MD, Lane, Tim, PhD, Flores, Stephen A, PhD, Fenton, Kevin A, MD, Wilson, Patrick A, PhD, Steiner, Riley, MPH, Heilig, Charles M, PhD

“…Summary Pooled estimates from across the African diaspora show that black men who have sex with men (MSM) are 15 times more likely to be HIV positive compared…”
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