Search Results - "Heil, Emily"
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1
Put the Fluoroquinolone Down and No One Gets Hurt
Published in Clinical infectious diseases (19-07-2024)Get full text
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New Perspectives on Antimicrobial Agents: Cefiderocol
Published in Antimicrobial agents and chemotherapy (16-07-2021)“…Bacterial resistance to carbapenem agents has reached alarming levels. Accordingly, collaborative efforts between national and international organizations and…”
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The Goldilocks Time for Remdesivir — Is Any Indication Just Right?
Published in The New England journal of medicine (27-01-2022)“…For 2 years, we have been under siege by a lingering global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In an ideal world,…”
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Considerations for Empiric Antimicrobial Therapy in Sepsis and Septic Shock in an Era of Antimicrobial Resistance
Published in The Journal of infectious diseases (21-07-2020)“…Patients with sepsis present across a spectrum of infection sites and severity of illnesses requiring complex decision making at the bedside as to when prompt…”
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Toward More Rational Time-to-Antibiotic Metrics for Suspected Sepsis
Published in Critical care medicine (01-05-2021)Get full text
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Optimizing Pharmacokinetics-Pharmacodynamics of Antimicrobial Management in Patients with Sepsis: A Review
Published in The Journal of infectious diseases (21-07-2020)“…Critically ill patients with sepsis or septic shock are at an increased risk of death. Early and aggressive interventions are essential for improving clinical…”
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Cefiderocol: the Trojan horse has arrived but will Troy fall?
Published in The Lancet infectious diseases (01-02-2021)“…Since other similar trials have not enrolled patients infected with carbapenem-resistant A baumannii, it seems unfair to compare cefiderocol's high mortality…”
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Infectious Diseases Society of America Position Paper: Recommended Revisions to the National Severe Sepsis and Septic Shock Early Management Bundle (SEP-1) Sepsis Quality Measure
Published in Clinical infectious diseases (16-02-2021)“…Abstract The Centers for Medicare & Medicaid Services’ Severe Sepsis and Septic Shock Early Management Bundle (SEP-1) measure has appropriately established…”
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A Population Pharmacokinetics and Pharmacodynamic Approach To Optimize Tazobactam Activity in Critically Ill Patients
Published in Antimicrobial agents and chemotherapy (21-02-2020)“…The percentage of the time that the free drug concentration remains above a concentration threshold (% > concentration threshold) has frequently been…”
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Considerations for long-acting antiretroviral therapy in older persons with HIV
Published in AIDS (London) (01-12-2023)“…People with HIV (PWH) can now enjoy longer, healthier lives due to safe and highly effective antiretroviral therapy (ART), and improved care and prevention…”
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What Is Left to Tackle in Inpatient Antimicrobial Stewardship Practice and Research
Published in Infectious disease clinics of North America (01-12-2023)“…Despite widespread uptake of antimicrobial stewardship in acute care hospitals, there is ongoing need for innovation and optimization of ASPs. This article…”
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Probable hepatotoxicity from two second-generation integrase strand transfer inhibitors
Published in AIDS (London) (01-11-2021)Get full text
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Change in hospital antibiotic use and acquisition of multidrug-resistant gram-negative organisms after the onset of coronavirus disease 2019
Published in Infection control and hospital epidemiology (01-09-2021)“…Interrupted time series segmented regression was conducted to trend antibiotic use and multidrug-resistant gram-negative (MDRGN) acquisition relative to…”
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Penicillin skin testing in methicillin-sensitive staphylococcus aureus bacteremia: A cost-effectiveness analysis
Published in PloS one (07-01-2019)“…Beta-lactams are the mainstay for treating methicillin-susceptible Staphylococcus aureus (MSSA) infections complicated by bacteremia due to superior outcomes…”
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Pharmacodynamic Target Attainment for Cefepime, Meropenem, and Piperacillin-Tazobactam Using a Pharmacokinetic/Pharmacodynamic-Based Dosing Calculator in Critically Ill Patients
Published in Antimicrobial agents and chemotherapy (01-09-2018)“…This was a prospective study to determine if pharmacokinetic/pharmacodynamic (PK/PD)-based antibiotic dosing software aids in achieving concentration targets…”
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Evaluation of Linezolid Pharmacokinetics in Critically Ill Obese Patients with Severe Skin and Soft Tissue Infections
Published in Antimicrobial agents and chemotherapy (20-01-2021)“…Linezolid standard dosing is fixed at 600 mg every 12 h (q12h) for adults. Literature suggests critically ill, obese patients require higher doses. The study…”
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In a Pinch: Cefiderocol for CRAB Infections
Published in Antimicrobial agents and chemotherapy (17-05-2022)“…Carbapenem-resistant Acinetobacter baumannii (CRAB) can cause significant infections with limited treatment options available. Falcone et al…”
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The Economics of Penicillin Allergy Testing: Still Scratching the Value Surface
Published in Clinical infectious diseases (15-03-2021)Get full text
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It Is a Marathon, Not a Sprint—Sustainability of Stewardship in ICUs
Published in Critical care medicine (01-01-2021)Get full text
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