Search Results - "Heiko Henze"

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa by Srinivas, Nityakalyani, Jetter, Peter, Ueberbacher, Bernhard J, Werneburg, Martina, Zerbe, Katja, Steinmann, Jessica, Van der Meijden, Benjamin, Bernardini, Francesca, Lederer, Alexander, Dias, Ricardo L.A, Misson, Pauline E, Henze, Heiko, Zumbrunn, Jürg, Gombert, Frank O, Obrecht, Daniel, Hunziker, Peter, Schauer, Stefan, Ziegler, Urs, Käch, Andres, Eberl, Leo, Riedel, Kathrin, DeMarco, Steven J, Robinson, John A

“…Antibiotics with new mechanisms of action are urgently required to combat the growing health threat posed by resistant pathogenic microorganisms. We…”
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Discovery of Highly Potent and Selective CXCR4 Inhibitors Using Protein Epitope Mimetics (PEM) Technology by Alexander Lederer, John A. Robinson, Kerstin Moehle, Thomas Klimkait, François Hamy, Vincent Brondani, Sergio Lociuro, Jean-Pierre Obrecht, Jan Willem Vrijbloed, Christian Ludin, Frank O. Gombert, Federico Brianza, Jürg Zumbrunn, Reshmi Mukherjee, Barbara Romagnoli, Heiko Henze, Steven J. DeMarco, Daniel Obrecht

“…Novel, highly potent CXCR4 inhibitors with good pharmacokinetic properties were obtained by applying PEM technology starting from the naturally occurring…”
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Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles by DeMarco, Steven J., Henze, Heiko, Lederer, Alexander, Moehle, Kerstin, Mukherjee, Reshmi, Romagnoli, Barbara, Robinson, John A., Brianza, Federico, Gombert, Frank O., Lociuro, Sergio, Ludin, Christian, Vrijbloed, Jan Willem, Zumbrunn, Jürg, Obrecht, Jean-Pierre, Obrecht, Daniel, Brondani, Vincent, Hamy, François, Klimkait, Thomas

“…Protein epitope mimetics (PEM) of Polyphemusin II act as highly potent CXCR4 inhibitors with good in vivo pharmacokinetic properties. Novel highly potent CXCR4…”
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