Comparison of Clinpro Cario L-Pop estimates with CIA lactic acid estimates of the oral microflora

Clinpro Cario L‐Pop (CCLP) is a semiquantitive test claimed to determine the general potential for caries development and to monitor the individual caries risk. This test translates the capacity of the tongue microflora to produce lactic acid into a score of 1–9, indicating a low, medium or high ris...

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Bibliographic Details
Published in:	European journal of oral sciences Vol. 114; no. 2; pp. 128 - 132
Main Authors:	Gerardu, Véronique, Heijnsbroek, Muriel, Buijs, Mark, Van Der Weijden, Fridus, Ten Cate, Bob, Van Loveren, Cor
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01-04-2006
Subjects:	Adult Anti-Infective Agents, Local - therapeutic use Bacteria - drug effects Bacteria - metabolism Biofilms - drug effects clinical trial Cross-Over Studies Dental Caries Activity Tests Dental Caries Susceptibility dental plaque Dental Plaque - microbiology Dentistry Electrophoresis, Capillary Female Follow-Up Studies Humans lactic acid Lactic Acid - analysis Male Mouthwashes - therapeutic use Oral Hygiene Sucrose - metabolism tongue Tongue - microbiology Toothpastes - therapeutic use
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Summary:	Clinpro Cario L‐Pop (CCLP) is a semiquantitive test claimed to determine the general potential for caries development and to monitor the individual caries risk. This test translates the capacity of the tongue microflora to produce lactic acid into a score of 1–9, indicating a low, medium or high risk for caries development. The aim of this randomized crossover, clinical trial was to evaluate the CCLP on its variation over time and its capacity to monitor the effect of three different oral hygiene procedures. The CCLP readings were compared with measurements of lactic acid in tongue biofilm and plaque samples by capillary ion electrophoresis (CIA). After four washout periods, the distribution of scores in the low‐, medium‐, and high‐risk categories was 10%, 16%, and 74%, respectively. Out of 30 subjects, 11 scored consistently in the same category. The coefficients of variance of lactic acid concentrations were 31% for tongue samples and 25% for plaque samples. After using antimicrobial toothpaste and mouthwash, the number of high‐risk scores was reduced to 33%; reduced acidogenicity was also found in tongue and plaque samples. We conclude that CCLP can be used to monitor and stimulate compliance to an antimicrobial oral hygiene protocol.
Bibliography:	istex:335B9F552C4A083732899D7C85F50397FE8F2F68 ArticleID:EOS345 ark:/67375/WNG-BD1Z20V3-Z ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-News-1 ObjectType-Feature-3
ISSN:	0909-8836 1600-0722
DOI:	10.1111/j.1600-0722.2006.00345.x