Search Results - "Heijer, Tom den"

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  1. 1

    Cerebral hypoperfusion and clinical onset of dementia: The Rotterdam study by Ruitenberg, Annemieke, den Heijer, Tom, Bakker, Stef L. M., van Swieten, John C., Koudstaal, Peter J., Hofman, Albert, Breteler, Monique M. B.

    Published in Annals of neurology (01-06-2005)
    “…Cerebral blood flow (CBF) velocity is decreased in patients with Alzheimer's disease. It is being debated whether this reflects diminished demand because of…”
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  2. 2

    Brain tissue volumes in relation to cognitive function and risk of dementia by Ikram, M. Arfan, Vrooman, Henri A, Vernooij, Meike W, Heijer, Tom den, Hofman, Albert, Niessen, Wiro J, van der Lugt, Aad, Koudstaal, Peter J, Breteler, Monique M.B

    Published in Neurobiology of aging (01-03-2010)
    “…Abstract We investigated in a population-based cohort study the association of global and lobar brain tissue volumes with specific cognitive domains and risk…”
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    Structural and functional brain connectivity in presymptomatic familial frontotemporal dementia by DOPPER, Elise G. P, ROMBOUTS, Serge A. R. B, BUCHEM, Mark A. Van, RIZZU, Patrizia, SWIETEN, John C. Van, JISKOOT, Lize C, DEN HEIJER, Tom, DE GRAAF, J. Roos A, DE KONING, Inge, HAMMERSCHLAG, Anke R, SEELAAR, Harro, SEELEY, William W, VEER, Ilya M

    Published in Neurology (26-02-2013)
    “…We aimed to investigate whether cognitive deficits and structural and functional connectivity changes can be detected before symptom onset in a large cohort of…”
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  4. 4

    Total antioxidant capacity of the diet and major neurologic outcomes in older adults by DEVORE, Elizabeth E, FESKENS, Edith, ARFAN IKRAM, M, DEN HEIJER, Tom, VERNOOIJ, Meike, DER LIJN, Fedde Van, HOFMAN, Albert, NIESSEN, Wiro J, BRETELER, Monique M. B

    Published in Neurology (05-03-2013)
    “…To evaluate total antioxidant capacity of the diet, measured by the ferric-reducing antioxidant power (FRAP) assay, in relation to risks of dementia and…”
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  5. 5

    Association between blood pressure levels over time and brain atrophy in the elderly by Heijer, Tom den, Skoog, Ingmar, Oudkerk, Matthijs, de Leeuw, Frank-Erik, de Groot, Jan Cees, Hofman, Albert, Breteler, Monique M.B

    Published in Neurobiology of aging (01-03-2003)
    “…The relation between blood pressure level and degree of global brain atrophy is equivocal. We evaluated past and present blood pressure levels and change in…”
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  6. 6

    Structural and functional brain connectivity in presymptomatic familial frontotemporal dementia by Dopper, Elise G.P, Rombouts, Serge A.R.B, Jiskoot, Lize C, den Heijer, Tom, de Graaf, J. Roos A, de Koning, Inge, Hammerschlag, Anke R, Seelaar, Harro, Seeley, William W, Veer, Ilya M, van Buchem, Mark A, Rizzu, Patrizia, van Swieten, John C

    Published in Neurology (08-07-2014)
    “…OBJECTIVE:We aimed to investigate whether cognitive deficits and structural and functional connectivity changes can be detected before symptom onset in a large…”
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  7. 7

    Hippocampus segmentation in MR images using atlas registration, voxel classification, and graph cuts by van der Lijn, Fedde, den Heijer, Tom, Breteler, Monique M.B., Niessen, Wiro J.

    Published in NeuroImage (Orlando, Fla.) (01-12-2008)
    “…Since hippocampal volume has been found to be an early biomarker for Alzheimer's disease, there is large interest in automated methods to accurately, robustly,…”
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  8. 8

    Presymptomatic cognitive decline in familial frontotemporal dementia: A longitudinal study by Jiskoot, Lize C, Dopper, Elise G.P, Heijer, Tom den, Timman, Reinier, van Minkelen, Rick, van Swieten, John C, Papma, Janne M

    Published in Neurology (26-07-2016)
    “…OBJECTIVE:In this prospective cohort study, we performed a 2-year follow-up study with neuropsychological assessment in the presymptomatic phase of familial…”
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  9. 9

    Silent Brain Infarcts and the Risk of Dementia and Cognitive Decline by Vermeer, Sarah E, Prins, Niels D, den Heijer, Tom, Hofman, Albert, Koudstaal, Peter J, Breteler, Monique M.B

    Published in The New England journal of medicine (27-03-2003)
    “…Silent brain infarcts (i.e., infarcts without associated neurologic symptoms) are common, and their clinical significance is unclear. In this population-based…”
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  10. 10

    Incidence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study by VERMEER, Sarah E, DEN HEIJER, Tom, KOUDSTAAL, Peter J, OUDKERK, Matthijs, HOFMAN, Albert, BRETELER, Monique M. B

    Published in Stroke (1970) (01-02-2003)
    “…The prevalence of silent brain infarcts in healthy elderly people is high, and these lesions are associated with an increased risk of stroke. The incidence of…”
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  11. 11

    A Study of the Bidirectional Association Between Hippocampal Volume on Magnetic Resonance Imaging and Depression in the Elderly by den Heijer, Tom, Tiemeier, Henning, Luijendijk, Hendrika J, van der Lijn, Fedde, Koudstaal, Peter J, Hofman, Albert, Breteler, Monique M.B

    Published in Biological psychiatry (1969) (15-07-2011)
    “…Background Hippocampal volume loss on magnetic resonance imaging (MRI) has been reported in patients with depression. It is uncertain whether a small…”
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    Alcohol intake in relation to brain magnetic resonance imaging findings in older persons without dementia by DEN HEIJER, Torn, VERMEER, Sarah E, VAN DIJK, Ewoud J, PRINS, Niels D, KOUDSTAAL, Peter J, VAN DUIJN, Cornelia M, HOFMAN, Albert, BRETELER, Monique M. B

    Published in The American journal of clinical nutrition (01-10-2004)
    “…Consumers of light-to-moderate amounts of alcohol have a lower risk of dementia and, possibly, Alzheimer disease than do abstainers. Because vascular disease…”
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  16. 16

    The thyroid hormone receptor alpha locus and white matter lesions: a role for the clock gene REV-ERBα by Medici, Marco, Ikram, M Arfan, van der Lijn, Fedde, den Heijer, Tom, Vernooij, Meike W, Hofman, Albert, Niessen, Wiro J, Visser, Theo J, Breteler, Monique M B, Peeters, Robin P

    Published in Thyroid (New York, N.Y.) (01-11-2012)
    “…Thyroid disorders are associated with an increased risk of cognitive impairment and Alzheimer's disease. Both small vessel disease and neurodegeneration have a…”
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  17. 17

    Cerebral haemodynamics in the elderly: the rotterdam study by Bakker, Stef L M, de Leeuw, Frank-Erik, den Heijer, Tom, Koudstaal, Peter J, Hofman, Albert, Breteler, Monique M B

    Published in Neuroepidemiology (01-07-2004)
    “…Transcranial Doppler ultrasonography allows the non-invasive assessment of cerebral haemodynamics. Data on the frequency distribution of these parameters in…”
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    ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdala by Sleegers, Kristel, den Heijer, Tom, van Dijk, Ewoud J., Hofman, Albert, Bertoli-Avella, Aida M., Koudstaal, Peter J., Breteler, Monique M.B., van Duijn, Cornelia M.

    Published in Neurobiology of aging (01-08-2005)
    “…Despite biological support for a role of angiotensin converting enzyme (ACE) in Alzheimer's disease (AD), studies assessing the ACE I/D polymorphism in AD are…”
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  19. 19

    Cerebral white matter lesions and the risk of dementia by Prins, Niels D, van Dijk, Ewoud J, den Heijer, Tom, Vermeer, Sarah E, Koudstaal, Peter J, Oudkerk, Matthijs, Hofman, Albert, Breteler, Monique M B

    Published in Archives of neurology (Chicago) (01-10-2004)
    “…To study the association between white matter lesions (WML) in specific locations and the risk of dementia. The Rotterdam Scan Study, a prospective…”
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    Matrix metalloproteinase 3 haplotypes and dementia and Alzheimer's disease. The Rotterdam Study by Reitz, Christiane, van Rooij, Frank J A, de Maat, Moniek P M, den Heijer, Tom, Hofman, Albert, Witteman, Jacqueline C M, Breteler, Monique M B

    Published in Neurobiology of aging (01-06-2008)
    “…Evidence by post-mortem and animal studies suggests that matrix metalloproteinases (MMPs) may play an important role in the pathophysiology of Alzheimer's…”
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