Search Results - "Heijdra, J. M."
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Analysis of current perioperative management with Haemate® P/Humate P® in von Willebrand disease: Identifying the need for personalized treatment
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2018)“…Introduction Patients with Von Willebrand disease (VWD) are regularly treated with VWF‐containing concentrates in case of acute bleeding, trauma and dental or…”
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Mixed effect estimation in deep compartment models: Variational methods outperform first-order approximations
Published in Journal of pharmacokinetics and pharmacodynamics (04-07-2024)“…This work focusses on extending the deep compartment model (DCM) framework to the estimation of mixed-effects. By introducing random effects, model predictions…”
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Population pharmacokinetics of factor IX in hemophilia B patients undergoing surgery
Published in Journal of thrombosis and haemostasis (01-11-2018)“…Essentials Factor IX (FIX) dosing using body weight frequently results in under and overdosing during surgery. We aimed to establish a population…”
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Long-term cost-effectiveness of case-finding and mass-screening for coeliac disease in children
Published in Gastroenterology (New York, N.Y. 1943) (29-07-2024)“…Celiac disease (CD) is a common yet underdiagnosed autoimmune disease with substantial long-term consequences. High-accuracy point-of-care tests (POCTs) for CD…”
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Is pharmacokinetic-guided dosing of desmopressin and von Willebrand factor-containing concentrates in individuals with von Willebrand disease or low von Willebrand factor reliable and feasible? A protocol for a multicentre, non-randomised, open label cohort trial, the OPTI-CLOT: to WiN study
Published in BMJ open (15-02-2022)“…IntroductionVon Willebrand disease (VWD) is a bleeding disorder, caused by a deficiency or defect of von Willebrand factor (VWF). In case of medical procedures…”
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