Search Results - "Heigenhauser, George J."

Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle by Perry, Christopher G. R., Lally, James, Holloway, Graham P., Heigenhauser, George J. F., Bonen, Arend, Spriet, Lawrence L.

“…Exercise training induces mitochondrial biogenesis, but the time course of molecular sequelae that accompany repetitive training stimuli remains to be…”
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Six sessions of sprint interval training increases muscle oxidative potential and cycle endurance capacity in humans by Burgomaster, Kirsten A, Hughes, Scott C, Heigenhauser, George J. F, Bradwell, Suzanne N, Gibala, Martin J

“…1 Exercise Metabolism Research Group, Department of Kinesiology, and 2 Department of Medicine, McMaster University, Hamilton, Ontario, Canada Submitted 1…”
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Effect of short-term sprint interval training on human skeletal muscle carbohydrate metabolism during exercise and time-trial performance by Burgomaster, Kirsten A, Heigenhauser, George J. F, Gibala, Martin J

“…1 Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario; and 2 Department of Medicine, McMaster University,…”
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Two weeks of high-intensity aerobic interval training increases the capacity for fat oxidation during exercise in women by Talanian, Jason L, Galloway, Stuart D. R, Heigenhauser, George J. F, Bonen, Arend, Spriet, Lawrence L

“…1 Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada, 2 Department of Sport Studies, University of Stirling,…”
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Endurance training in obese humans improves glucose tolerance and mitochondrial fatty acid oxidation and alters muscle lipid content by Bruce, Clinton R, Thrush, A Brianne, Mertz, Valerie A, Bezaire, Veronic, Chabowski, Adrian, Heigenhauser, George J F, Dyck, David J

“…Muscle fatty acid (FA) metabolism is impaired in obesity and insulin resistance, reflected by reduced rates of FA oxidation and accumulation of lipids. It has…”
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Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle by Song, Zhe, Moore, Daniel R., Hodson, Nathan, Ward, Carl, Dent, Jessica R., O’Leary, Mary F., Shaw, Andrew M., Hamilton, D. Lee, Sarkar, Sovan, Gangloff, Yann-Gaël, Hornberger, Troy A., Spriet, Lawrence L., Heigenhauser, George J., Philp, Andrew

“…The mechanistic target of rapamycin (mTOR) is a central mediator of protein synthesis in skeletal muscle. We utilized immunofluorescence approaches to study…”
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High-intensity aerobic interval training increases fat and carbohydrate metabolic capacities in human skeletal muscle by Perry, Christopher G R, Heigenhauser, George J F, Bonen, Arend, Spriet, Lawrence L

“…High-intensity aerobic interval training (HIIT) is a compromise between time-consuming moderate-intensity training and sprint-interval training requiring…”
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Beetroot Juice Increases Human Muscle Force without Changing Ca2+-Handling Proteins by WHITFIELD, JAMIE, GAMU, DANIEL, HEIGENHAUSER, GEORGE J F, VAN LOON, LUC J C, SPRIET, LAWRENCE L, TUPLING, A RUSSELL, HOLLOWAY, GRAHAM P

“…Dietary inorganic nitrate (NO3) supplementation improves skeletal muscle (SkM) contractile efficiency, and although rodent literature has suggested…”
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Effects of Dehydration during Cycling on Skeletal Muscle Metabolism in Females by LOGAN-SPRENGER, Heather M, HEIGENHAUSER, George J. F, KILLIAN, Kieran J, SPRIET, Lawrence L

“…This study investigated the effects of progressive dehydration on the time course of changes to whole body substrate oxidation and skeletal muscle metabolism…”
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Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle by Perry, Christopher G. R., Kane, Daniel A., Herbst, Eric A. F., Mukai, Kazutaka, Lark, Daniel S., Wright, David C., Heigenhauser, George J. F., Neufer, P. Darrell, Spriet, Lawrence L., Holloway, Graham P.

“…Key point •  ATP transfer from mitochondria to the cytoplasm occurs mainly through phosphate transfer to creatine by mitochondrial creatine kinase (miCK) but…”
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High-intensity interval training increases SIRT1 activity in human skeletal muscle by Gurd, Brendon J, Perry, Christopher G R, Heigenhauser, George J F, Spriet, Lawrence L, Bonen, Arend

“…The effects of training on silent mating-type information regulator 2 homolog 1 (SIRT1) activity and protein in relationship to peroxisome…”
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Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise by Holloway, Graham P., Bezaire, Veronic, Heigenhauser, George J. F., Tandon, Narendra N., Glatz, Jan F. C., Luiken, Joost J. F. P., Bonen, Arend, Spriet, Lawrence L.

“…Mitochondrial fatty acid transport is a rate-limiting step in long chain fatty acid (LCFA) oxidation. In rat skeletal muscle, the transport of LCFA at the…”
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Skeletal muscle mitochondrial FAT/CD36 content and palmitate oxidation are not decreased in obese women by Holloway, Graham P, Thrush, A Brianne, Heigenhauser, George J F, Tandon, Narendra N, Dyck, David J, Bonen, Arend, Spriet, Lawrence L

“…A reduction in fatty acid oxidation has been associated with lipid accumulation and insulin resistance in the skeletal muscle of obese individuals. We examined…”
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Exercise training increases sarcolemmal and mitochondrial fatty acid transport proteins in human skeletal muscle by Talanian, Jason L, Holloway, Graham P, Snook, Laelie A, Heigenhauser, George J F, Bonen, Arend, Spriet, Lawrence L

“…Fatty acid oxidation is highly regulated in skeletal muscle and involves several sites of regulation, including the transport of fatty acids across both the…”
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Incorporation of Omega-3 Fatty Acids Into Human Skeletal Muscle Sarcolemmal and Mitochondrial Membranes Following 12 Weeks of Fish Oil Supplementation by Gerling, Christopher J, Mukai, Kazutaka, Chabowski, Adrian, Heigenhauser, George J F, Holloway, Graham P, Spriet, Lawrence L, Jannas-Vela, Sebastian

“…Fish oil (FO) supplementation in humans results in the incorporation of omega-3 fatty acids (FAs) eicosapentaenoic acid (EPA; C20:5) and docosahexaenoic acid…”
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Seven days of oral taurine supplementation does not increase muscle taurine content or alter substrate metabolism during prolonged exercise in humans by Galloway, Stuart D. R, Talanian, Jason L, Shoveller, Anna K, Heigenhauser, George J. F, Spriet, Lawrence L

“…1 Department of Sports Studies, University of Stirling, Stirling, United Kingdom; Departments of 2 Human Health and Nutritional Sciences and 3 Animal and…”
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Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation by Bezaire, Veronic, Bruce, Clinton R, Heigenhauser, George J F, Tandon, Narendra N, Glatz, Jan F C, Luiken, Joost J J F, Bonen, Arend, Spriet, Lawrence L

“…Fatty acid translocase (FAT/CD36) is a transport protein with a high affinity for long-chain fatty acids (LCFA). It was recently identified on rat skeletal…”
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Hyperoxia decreases muscle glycogenolysis, lactate production, and lactate efflux during steady-state exercise by Stellingwerff, Trent, Leblanc, Paul J, Hollidge, Melanie G, Heigenhauser, George J F, Spriet, Lawrence L

“…The aim of this study was to determine whether the decreased muscle and blood lactate during exercise with hyperoxia (60% inspired O2) vs. room air is due to…”
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AMP‐activated protein kinase is required for exercise‐induced peroxisome proliferator‐activated receptor γ co‐activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle by Smith, Brennan K., Mukai, Kazutaka, Lally, James S., Maher, Amy C., Gurd, Brendon J., Heigenhauser, George J. F., Spriet, Lawrence L., Holloway, Graham P.

“…Key points The transcriptional co‐activator peroxisome proliferator‐activated receptor γ co‐activator 1α (PGC‐1α), in concert with mitochondrial transcription…”
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Leptin increases FA oxidation in lean but not obese human skeletal muscle: evidence of peripheral leptin resistance by Steinberg, Gregory R, Parolin, Michelle L, Heigenhauser, George J F, Dyck, David J

“…The adipocyte-derived hormone leptin has been shown to acutely increase fatty acid (FA) oxidation and decrease esterification in resting rodent skeletal…”
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