Search Results - "Heider, Robin M."
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An Assay that Predicts In Vivo Efficacy for DNA Aptamers that Stimulate Remyelination in a Mouse Model of Multiple Sclerosis
Published in Molecular therapy. Methods & clinical development (15-06-2018)“…Multiple sclerosis (MS) is a debilitating disease for which regenerative therapies are sought. We have previously described human antibodies and DNA…”
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IL17RB genetic variants are associated with acamprosate treatment response in patients with alcohol use disorder: A proteomics-informed genomics study
Published in Brain, behavior, and immunity (01-08-2024)“…•Baseline plasma inflammatory markers were associated with acamprosate treatment outcomes.•Lower baseline IL17RB expression was associated with alcohol…”
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Optimization of a 40-mer Antimyelin DNA Aptamer Identifies a 20-mer with Enhanced Properties for Potential Multiple Sclerosis Therapy
Published in Nucleic acid therapeutics (01-06-2019)“…We previously reported the selection and characterization of a DNA aptamer capable of stimulating remyelination in a mouse model of multiple sclerosis. This…”
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A comparison of human natural monoclonal antibodies and aptamer conjugates for promotion of CNS remyelination: where are we now and what comes next?
Published in Expert opinion on biological therapy (04-05-2018)“…Multiple sclerosis (MS) is a chronic and progressive inflammatory demyelinating disease of the human central nervous system (CNS) and is the most common…”
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