Search Results - "Heidenreich, R."

13.04 Improving the efficacy of TCRtg T cell therapy for solid tumors with mRNA-based vaccination by Krueger, J, Lutz, J, Ruotsalainen, J, Mülfarth, R, Heidenreich, R

“…BackgroundIn recent years, adoptive T cell therapy (ACT) has demonstrated significant effectiveness in treating hematological malignancies. Yet, the clinical…”
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Contrast letter acuity as a visual component for the Multiple Sclerosis Functional Composite by BALCER, L. J, BAIER, M. L, HEIDENREICH, F. R, JACOBS, D. A, MARKOWITZ, C. E, STUART, W. H, YING, G.-S, GALETTA, S. L, MAGUIRE, M. G, CUTTER, G. R, COHEN, J. A, KOOIJMANS, M. F, SANDROCK, A. W, NANO-SCHIAVI, M. L, PFOHL, D. C, MILLS, M, BOWEN, J, FORD, C

“…Visual dysfunction is one of the most common causes of disability in multiple sclerosis (MS). The Multiple Sclerosis Functional Composite (MSFC), a new…”
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Phase I dose-escalation and expansion study of intratumoral CV8102, a RNA-based TLR- and RIG-1 agonist in patients with advanced solid tumors by Terheyden, P., Weishaupt, C., Heinzerling, L., Klinkhardt, U., Krauss, J., Mohr, P., Kiecker, F., Becker, J.C., Dähling (Submitter, A., Döner, F., Heidenreich, R., Scheel, B., Schönborn-Kellenberger, O., Seibel, T., Gnad-Vogt, U.

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Discovery to first-in-man studies of a multi-peptide-based hepatocellular carcinoma vaccine adjuvanted with CV8102 (RNAdjuvant) – HEPAVAC by Mayer, A, Accolla, R, Ma, Y.T, Heidenreich, R, Koenigsrainer, A, Izzo, F, Loeffler, M, Flohr, C, Mueller, P, Kutscher, S, Rammensee, H.-G, Sangro, B, Francque, S, Valmori, D, Weinschenk, T, Reinhardt, C, Gnad-Vogt, U, Singh-Jasuja, H, Buonaguro, L

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Fumaric aciduria: Clinical and imaging features by Kerrigan, John F., Aleck, Kirk A., Tarby, Theodore J., Bird, C. Roger, Heidenreich, Randall A.

“…Fumaric aciduria (fumaric acidemia, fumarase deficiency) is a rare inborn error of metabolism caused by deficient activity of fumarate hydratase, one of the…”
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Pharmacological and genetic modifications of somatic cholesterol do not substantially alter the course of CNS disease in Niemann–Pick C mice by Erickson, R. P., Garver, W. S., Camargo, F., Hossian, G. S., Heidenreich, R. A.

“…Niemann–Pick type C (NPC) is a neurodegenerative disorder with somatically altered cholesterol metabolism. The NPC1 gene has recently been cloned and shown to…”
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Impaired ABCA1-dependent Lipid Efflux and Hypoalphalipoproteinemia in Human Niemann-Pick type C Disease by Choi, Hong Y., Karten, Barbara, Chan, Teddy, Vance, Jean E., Greer, Wenda L., Heidenreich, Randall A., Garver, William S., Francis, Gordon A.

“…The cholesterol trafficking defect in Niemann-Pick type C (NPC) disease leads to impaired regulation of cholesterol esterification, cholesterol synthesis, and…”
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Tumor endothelium-specific transgene expression directed by vascular endothelial growth factor receptor-2 (Flk-1) promoter/enhancer sequences by HEIDENREICH, Regina, KAPPEL, Andreas, BREIER, Georg

“…The receptor tyrosine kinase Flk-1 plays a pivotal role in the development of the vascular system and in the vascularization of a wide variety of tumors. We…”
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Cyclodextrins in the treatment of a mouse model of Niemann-Pick C disease by Camargo, Fernando, Erickson, Robert P., Garver, William S., Hossain, G.Showkat, Carbone, Peter N., Heidenreich, Randall A., Blanchard, James

“…Niemann-Pick type C (NPC) is a neurodegenerative disorder characterized by greatly altered somatic cholesterol metabolism. The NPC1 gene has recently been…”
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383 PROTEIN VARIATION IN MOUSE LIVER WITH DIFFERENT NIEMANN-PICK TYPE C GENOTYPES by Meislin, M., Heidenreich, R.

“…Niemann-Pick type C (NPC) is an autosomal recessive disease that affects children at a young age with hepatosplenomegaly and neurodegeneration that ultimately…”
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Silica‐Bearing Mounds and Strata in the Southwest Melas Basin, Valles Marineris, Mars: Evidence for a Hydrothermal Origin by Rogers, Emma R., Qualizza, Briar R., Heidenreich, Joseph R., Dawson, Henry G., Horgan, Briony H. N.

“…A small basin on the Southwest (SW) margin of Melas Chasma in Valles Marineris, Mars, hosts a variety of previously identified sedimentary fans and layered…”
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Autosomal dominant inheritance pattern for trigger thumb by Shim, Veronica C, Admire, Anthony A, Heidenreich, R A, Samimi, Kian J

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Benefit of interferon β-1a on MSFC progression in secondary progressive MS by COHEN, J. A, CUTTER, G. R, TSAO, E. C, WHITAKER, J. N, FISCHER, J. S, GOODMAN, A. D, HEIDENREICH, F. R, KOOIJMANS, M. F, SANDROCK, A. W, RUDICK, R. A, SIMON, J. H, SIMONIAN, N. A

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Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors by Poncz, M, Eisman, R, Heidenreich, R, Silver, S M, Vilaire, G, Surrey, S, Schwartz, E, Bennett, J S

“…The platelet membrane glycoprotein IIb X IIIa heterodimer complex (GPIIb X IIIa) is the platelet receptor for adhesive proteins, containing binding sites for…”
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Rescue of neurodegeneration in Niemann–Pick C mice by a prion-promoter-driven Npc1 cDNA transgene by Loftus, Stacie K., Erickson, Robert P., Walkley, Steven U., Bryant, Mark A., Incao, Arturo, Heidenreich, Randall A., Pavan, William J.

“…Niemann–Pick disease type C (NPC) is a neurodegenerative disorder with major visceral complications, including liver disease that can be fatal before onset of…”
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Site-specific Phosphorylation of Tau Accompanied by Activation of Mitogen-activated Protein Kinase (MAPK) in Brains of Niemann-Pick Type C Mice by Sawamura, Naoya, Gong, Jian-Sheng, Garver, William S., Heidenreich, Randall A., Ninomiya, Haruaki, Ohno, Kousaku, Yanagisawa, Katsuhiko, Michikawa, Makoto

“…Niemann-Pick type C (NPC) disease is characterized by an accumulation of cholesterol in most tissues and progressive neurodegeneration with the formation of…”
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A missense mutation (1278T) in the cystathionine β-synthase gene prevalent in pyridoxine-responsive homocystinuria and associated with mild clinical phenotype by SHIH, V. E, FRINGER, J. M, MANDELL, R, KRAUS, J. P, BERRY, G. T, HEIDENREICH, R. A, KORSON, M. S, LEVY, H. L, RAMESH, V

“…Cystathionine beta-synthase (CBS) deficiency is an autosomal recessive disorder characterized by homocystinuria and multisystem clinical disease. Patients…”
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Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments by Garver, W S, Heidenreich, R A, Erickson, R P, Thomas, M A, Wilson, J M

“…Niemann-Pick type C (NPC) disease is characterized by an accumulation of cholesterol and other lipids in the lysosomal compartment. In this report, we use…”
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The Npc1 mutation causes an altered expression of caveolin-1, annexin II and protein kinases and phosphorylation of caveolin-1 and annexin II in murine livers by Garver, W.S, Hossain, G.S, Winscott, M.M, Heidenreich, R.A

“…We have previously demonstrated (1) an increased expression of caveolin-1 in murine heterozygous and homozygous Niemann-Pick type C (NPC) livers, and (2) an…”
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Retrospective analysis of incidence of maxillary pseudoarthrosis after orthognathic surgery: a review of 382 patients by Heidenreich, R., Kaba, S.C.P., Lemos, J.B.D., Bauer, H.C.

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