Search Results - "Heidemann, H. T."

Comparison of the Effects of Liposomal Amphotericin B and Conventional Amphotericin B on Propafenone Metabolism and Hepatic Cytochrome P-450 in Rats by INSELMANN, G, VOLKMANN, A, HEIDEMANN, H. T

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Amphotericin B and liver function by Inselmann, G, Inselmann, U, Heidemann, H.T

“…Amphotericin B is well established as a highly efficacious agent against systemic fungal infections in humans. The therapeutic potential of amphotericin B is…”
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Liposomal amphotericin B (AmBisome®) application and hepatic microsomal enzyme function in the rat by Inselmann, G., Schimanski, Anna, Jahns, R., Heidemann, H. T.

“…In the present study we investigated the influence of AmBisome®, a lyophilized liposomal amphotericin B formulation on various hepatic cytochrome…”
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Enhancement of cyclosporin A induced hepato- and nephrotoxicity by glutathione depletion by Inselmann, G, Lawerenz, H U, Nellessen, U, Heidemann, H T

“…The role of glutathione in cyclosporin A (cyclosporin) hepato- and nephrotoxicity has not been clarified yet. The hypothesis that a glutathione deficit…”
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Effect of aminophylline on cisplatin nephrotoxicity in the rat by Heidemann, H.Th, Müller, St, Mertins, L., Stepan, G., Hoffmann, K., Ohnhaus, E.E.

“…1 The effect of the methylxanthine aminophylline on cisplatin (5 mg kg−1 i.v.)‐induced acute renal failure was investigated in the rat. Renal function was…”
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Acute and chronic effects of flucytosine on amphotericin B nephrotoxicity in rats by HEIDEMANN, H. T, BRUNE, K. H, SABRA, R, BRANCH, R. A

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Antipyrine elimination in patients with alcoholic and non-alcoholic cirrhosis by Wensing, G, Hoffmann, K, Heidemann, H T

“…The metabolism of antipyrine to each of its three major metabolites 4-hydroxy-, 3-methylhydroxy- and norantipyrine has previously been demonstrated to be…”
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Modification of cisplatin-induced renal p-aminohippurate uptake alteration and lipid peroxidation by thiols, Ginkgo biloba extract, deferoxamine and torbafylline by Inselmann, G, Blöhmer, A, Kottny, W, Nellessen, U, Hänel, H, Heidemann, H T

“…To determine whether inhibition of lipid peroxidation modifies cisplatin-induced changes of renal p-aminohippurate (PAH) uptake, we examined the effects of…”
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Effect of chronic theophylline administration on amphotericin B nephrotoxicity in rats by Heidemann, H T, Bolten, M, Inselmann, G

“…The effect of chronic theophylline administration on amphotericin B nephrotoxicity was investigated in rats. A 7-day treatment of amphotericin B (5 mg/kg/day…”
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Amphotericin B nephrotoxicity in humans decreased by salt repletion by Heidemann, H T, Gerkens, J F, Spickard, W A, Jackson, E K, Branch, R A

“…A major limitation in the use of amphotericin B is its potential to cause nephrotoxicity. In animals, increased dietary sodium reduces renal toxicity…”
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Cyclosporin-A-induced lipid peroxidation in human liver microsomes and its influence on cytochrome P-450 by Inselmann, G, Barth, A, Engemann, R, Heidemann, H T

“…The present in vitro study using human liver tissue was performed to investigate the effect of cyclosporin A on lipid peroxidation and cytochrome P-450…”
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Effect of aminophylline on amphotericin B nephrotoxicity in the dog by Gerkens, J F, Heidemann, H T, Jackson, E K, Branch, R A

“…The polyene antibiotic, amphotericin B, causes an acute reduction in renal blood flow and glomerular filtration rate. The purpose of this study was to evaluate…”
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Effect of oral contraceptive steroids on the pharmacokinetics of phenprocoumon by Monig, H, Baese, C, Heidemann, HT, Ohnhaus, EE, Schulte, HM

“…1. The effect of chronic administration of oral contraceptive steroids (OCS) on the pharmacokinetics of the oral anticoagulant phenprocoumon was investigated…”
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Enzymuria following amphotericin B application in the rat by Inselmann, Gerhard, Balaschke, Michael, Heidemann, Hugo T.

“…Summary The effect of amphotericin B application on urinary renal tubule enzyme excretion was investigated in rats treated with amphotericin B (1.5 mg kg−1…”
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Effect of flucytosine on renal function in the rat by Heidemann, H T, Brune, K H

“…Flucytosine (5-fluorocytosine), a potent antimycotic drug against various systemic infections such as candidosis, aspergillosis and cryptococcosis, is…”
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Intrarenal hypertonic saline infusions in dogs with thoracic caval constriction by Heidemann, Hugo T.H., Jackson, Edwin K., Gerkens, John F., Branch, Robert A.

“…Intrarenal hypertonic saline infusions in dogs with thoracic caval constriction. Intrarenal artery infusions of hypertonic saline can activate tubuloglomerular…”
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Attenuation of cisplatinum-induced nephrotoxicity in the rat by high salt diet, furosemide and acetazolamide by HEIDEMANN, H. T, GERKENS, J. F, JACKSON, E. K, BRANCH, R. A

“…The influence of variations in sodium chloride diet, furosemide and acetazolamide on nephrotoxicity induced by cisplatinum have been investigated in the rat by…”
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Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment by Heidemann, H T, Kreuzfelder, E

“…A 54-year-old man was admitted to hospital with acute rhabdomyolysis and myoglobinuria due to hypokalemia. The hypokalemia was due to chronic licorice…”
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Pharmacokinetics of oral isosorbide-5-mononitrate in patients with ischemic heart failure by Meissner, A, Petersenn, S, Heidemann, H T, Osterkamp, U, Simon, R, Schulte, H M

“…This study compared the pharmacokinetics of orally administered isosorbide-5-mononitrate (20 mg) in patients with and without signs of ischemic heart failure…”
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Aminophylline inhibits renal vasoconstriction produced by intrarenal hypertonic saline by Gerkens, J F, Heidemann, H T, Jackson, E K, Branch, R A

“…An intrarenal infusion of hypertonic saline to sodium-depleted dogs causes an acute reduction in renal blood flow (RBF) which has been postulated to be due to…”
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