Search Results - "Heidema, A Geert"

The challenge for genetic epidemiologists: how to analyze large numbers of SNPs in relation to complex diseases by Heidema, A Geert, Boer, Jolanda M A, Nagelkerke, Nico, Mariman, Edwin C M, van der A, Daphne L, Feskens, Edith J M

“…Genetic epidemiologists have taken the challenge to identify genetic polymorphisms involved in the development of diseases. Many have collected data on large…”
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Plasma protein profiling reveals protein clusters related to BMI and insulin levels in middle-aged overweight subjects by van Dijk, Susan J, Feskens, Edith J M, Heidema, A Geert, Bos, Marieke B, van de Rest, Ondine, Geleijnse, Johanna M, de Groot, Lisette C P G M, Müller, Michael, Afman, Lydia A

“…Biomarkers that allow detection of the onset of disease are of high interest since early detection would allow intervening with lifestyle and nutritional…”
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Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain by Heidema, A. Geert, Wang, Ping, van Rossum, Caroline T.M, Feskens, Edith J.M, Boer, Jolanda M.A, Bouwman, Freek G, van't Veer, Pieter, Mariman, Edwin C.M

“…Abstract The human proteins ciliary neurotrophic factor (CNTF) and interleukin-6 (IL6) and their receptors share structural homology with leptin and its…”
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The Association of 83 Plasma Proteins with CHD Mortality, BMI, HDL-, and Total-Cholesterol in Men: Applying Multivariate Statistics To Identify Proteins with Prognostic Value and Biological Relevance by Heidema, A. Geert, Thissen, Uwe, Boer, Jolanda M. A, Bouwman, Freek G, Feskens, Edith J. M, Mariman, Edwin C. M

“…In this study, we applied the multivariate statistical tool Partial Least Squares (PLS) to analyze the relative importance of 83 plasma proteins in relation to…”
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A framework to identify physiological responses in microarray-based gene expression studies: selection and interpretation of biologically relevant genes by Rodenburg, Wendy, Heidema, A. Geert, Boer, Jolanda M. A, Bovee-Oudenhoven, Ingeborg M. J, Feskens, Edith J. M, Mariman, Edwin C. M, Keijer, Jaap

“…1 TI Food and Nutrition, Wageningen, The Netherlands 2 RIKILT-Institute of Food Safety, Wageningen, The Netherlands 3 NIZO Food Research, Ede, The Netherlands…”
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Analysis of multiple SNPs in genetic association studies: comparison of three multi-locus methods to prioritize and select SNPs by Heidema, A. Geert, Feskens, Edith J.M., Doevendans, Pieter A.F.M., Ruven, Henk J.T., van Houwelingen, Hans C., Mariman, Edwin C.M., Boer, Jolanda M.A.

“…Nonparametric approaches have been developed that are able to analyze large numbers of single nucleotide polymorphisms (SNPs) in modest sample sizes. These…”
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Developing a discrimination rule between breast cancer patients and controls using proteomics mass spectrometric data: a three-step approach by Heidema, A Geert, Nagelkerke, Nico

“…To discriminate between breast cancer patients and controls, we used a three-step approach to obtain our decision rule. First, we ranked the mass/charge values…”
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