Search Results - "Heidari, Mahmoud Reza"
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Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression
Published in Food and chemical toxicology (01-02-2018)“…In this study we investigated the protective effects and possible mechanisms of pirfenidone (PF) in paraquat (PQ)-induced lung injury and fibrosis in mice…”
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Evaluating the protective effect of metformin against diclofenac-induced oxidative stress and hepatic damage: In vitro and in vivo studies
Published in Biochemical and biophysical research communications (10-12-2023)“…Diclofenac (DIC) is one of the most commonly prescribed non-steroidal anti-inflammatory drugs and has been shown to cause oxidative stress and liver injury…”
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Combination of losartan with pirfenidone: a protective anti-fibrotic against pulmonary fibrosis induced by bleomycin in rats
Published in Scientific reports (16-04-2024)“…Pirfenidone (PFD), one acceptable medication for treating idiopathic pulmonary fibrosis (IPF), is not well tolerated by patients at full doses. Hence,…”
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Effect of safranal, a constituent of saffron, on olanzapine (an atypical antipsychotic) induced metabolic disorders in rat
Published in Iranian journal of basic medical sciences (01-12-2019)“…Olanzapine, an atypical antipsychotic, causes weight gain and metabolic disorders in humans. Safranal, one of the active components of (saffron), has been…”
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Investigating the effects of dihydroxyacetone on oxidative stress factors and histology of heart and liver tissue in acute aluminum phosphide poisoning
Published in Majallāh-i ʻilmī-i Dānishgāh-i ʻUlūm-i Pizishkī-i Kurdistān (01-03-2023)“…Background and Aim: Aluminum phosphide poisoning has a high mortality rate because of the production of phosphine gas and refractory hypotension. Based on the…”
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Prevalence of Aflatoxin Contamination in Herbs and Spices in Different Regions of Iran
Published in Iranian journal of public health (01-11-2017)“…Mycotoxins are natural toxins, produced by several fungal species and are associated with morbidity or even mortality in animals, plants, and humans. In this…”
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Effect of Crocus sativus extracts and its active constituent safranal on the harmaline-induced tremor in mice
Published in Iranian journal of basic medical sciences (01-05-2015)“…Due to unsatisfactory response or intolerable side effects of current drugs, treatment of essential tremor remains inadequate. Thus, we aimed to investigate…”
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Synthesis and antioxidant properties of substituted 3-benzylidene-7-alkoxychroman-4-ones
Published in Bioorganic & medicinal chemistry letters (15-12-2007)“…A series of substituted 3-benzylidene-7-alkoxychroman-4-ones were synthesized and evaluated for their antioxidant activities…”
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Evaluation of the analgesic effect of Echium amoenum Fisch & C.A. Mey. extract in mice: Possible mechanism involved
Published in Journal of ethnopharmacology (20-02-2006)“…Echium amoenum Fisch & C.A. Mey. has been used in Iranian traditional medicine as demulcent and analgesic in common cold from long ago. In this investigation,…”
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Alpha-mangostin Protects PC12 Cells Against Neurotoxicity Induced by Cadmium and Arsenic
Published in Biological trace element research (01-08-2023)“…Arsenic and cadmium are nonessential elements that are of importance in public health due to their high toxicity. Contact with these toxic elements, even in…”
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On the mechanisms by which theophylline changes core body temperature in mice
Published in European journal of pharmacology (12-05-1994)“…In the present work, the effects of neurotransmitter antagonists on theophylline-induced changes in body temperature were investigated. Intraperitoneal (i.p.)…”
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Preventive and therapeutic effects of azithromycin on acrylamide-induced neurotoxicity in rats
Published in Neurotoxicology (Park Forest South) (01-01-2024)“…Acrylamide (ACR) can induce neurotoxicity through different pathways, including oxidative stress and apoptosis. Azithromycin is well-known for its antioxidant…”
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Resveratrol Attenuates Learning, Memory, and Social Interaction Impairments in Rats Exposed to Arsenic
Published in BioMed research international (28-09-2021)“…Arsenic (As) toxicity has deleterious effects on human health causing disorder in the brain. The aim of this study was to investigate the possible…”
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Serum levels of Organochlorine Pesticides and Breast Cancer Risk in Iranian Women
Published in Archives of environmental contamination and toxicology (01-11-2019)“…Breast cancer is a multifactorial disease and its etiology is linked to multiple risk factors. There are shreds of controversial evidence that exposure to…”
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The effect of early handling on anxiety-like behaviors of rats exposed to valproic acid pre-and post-natally
Published in Neurotoxicology and teratology (01-01-2022)“…Autism spectrum disorder (ASD) is a complex, behaviorally defined disorder of the immature brain as a result of genetic and environmental risk factors, such as…”
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Losartan enhances the suppressive effect of pirfenidone on the bleomycin-induced epithelial-mesenchymal transition and oxidative stress in A549 cell line
Published in Iranian journal of basic medical sciences (01-01-2023)“…Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease. Despite the promising anti-fibrotic effect, the toleration of pirfenidone (PFD) by the patients in…”
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Comparison of Gastric-ulcerogenecity Effect of Methanolic Extract of Capparis spinosa and Indomethacin in Rat
Published in Jundishapur journal of natural pharmaceutical products (01-02-2021)“…Background: Several plants are used as analgesic in traditional medicine. Capparis spinosa (C. spinosa) is widely used for the treatment of gout and rheumatic…”
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Effect of methanolic extract of Hyoscymus niger L. on the seizure induced by picritoxin in mice
Published in Pakistan journal of pharmaceutical sciences (01-07-2009)“…Effects of Hyoscyamus niger L on central nervous system have been known for many years. The effects of methanolic extract of H. niger L. on seizures induced by…”
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Prevalence of Aflatoxin Contamination in Herbs and Spices in Different Regions of Iran
Published in Iranian journal of public health (01-11-2016)“…Abstract Background: Mycotoxins are natural toxins, produced by several fungal species and are associated with morbidity or even mortality in animals, plants,…”
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Comparison of gastric ulcerogenicity of percolated extract of Anacardium occidentale (cashew nut) with indomethacin in rats
Published in Pakistan journal of pharmaceutical sciences (01-01-2012)“…In traditional Iranian medicine, the core of the fruit of Anacardium occidentale (cashew nut) has been used in the management of the pain. In this study…”
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