Search Results - "Hei, Tom K"

Focus small to find big - the microbeam story by Wu, Jinhua, Hei, Tom K.

“…Purpose: Even though the first ultraviolet microbeam was described by S. Tschachotin back in 1912, the development of sophisticated micro-irradiation…”
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Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory signaling pathways and programed cell death by Gong, Xuezhong, Ivanov, Vladimir N., Davidson, Mercy M., Hei, Tom K.

“…Although kidney is a target organ of arsenic cytotoxicity, the underlying mechanisms of arsenic-induced nephrotoxicity remain poorly understood. As…”
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Retraction Note: Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures by Ivanov, Vladimir N., Grabham, Peter W., Wu, Cheng-Chia, Hei, Tom K.

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Cytoplasmic Irradiation Results in Mitochondrial Dysfunction and DRP1-Dependent Mitochondrial Fission by BO ZHANG, DAVIDSON, Mercy M, HONGNING ZHOU, CHUNXIN WANG, WALKER, Winsome F, HEI, Tom K

“…Direct DNA damage is often considered the primary cause of cancer in patients exposed to ionizing radiation or environmental carcinogens. Although mitochondria…”
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Graphene Oxide Attenuates the Cytotoxicity and Mutagenicity of PCB 52 via Activation of Genuine Autophagy by Liu, Yun, Wang, Xinan, Wang, Juan, Nie, Yaguang, Du, Hua, Dai, Hui, Wang, Jingjing, Wang, Mudi, Chen, Shaopeng, Hei, Tom K, Deng, Zhaoxiang, Wu, Lijun, Xu, An

“…Graphene oxide (GO), owing to its large surface area and abundance of oxygen-containing functional groups, is emerging as a potential adsorbent for…”
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The differential role of human macrophage in triggering secondary bystander effects after either gamma-ray or carbon beam irradiation by Dong, Chen, He, Mingyuan, Tu, Wenzhi, Konishi, Teruaki, Liu, Weili, Xie, Yuexia, Dang, Bingrong, Li, Wenjian, Uchihori, Yukio, Hei, Tom K, Shao, Chunlin

“…Highlights • A multi-cell line system was established to investigate the mechanisms of “abscopal effect”. • The secondary bystander injury caused by γ-rays was…”
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A role for TRAIL/TRAIL-R2 in radiation-induced apoptosis and radiation-induced bystander response of human neural stem cells by Ivanov, Vladimir N., Hei, Tom K.

“…Adult neurons, which are terminally differentiated cells, demonstrate substantial radioresistance. In contrast, human neural stem cells (NSC), which have a…”
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Mechanism of radiation-induced bystander effects: a unifying model by Hei, Tom K., Zhou, Hongning, Ivanov, Vladimir N., Hong, Mei, Lieberman, Howard B., Brenner, David J., Amundson, Sally A., Geard, Charles R.

“…The radiation‐induced bystander effect represents a paradigm shift in our understanding of the radiobiological effects of ionizing radiation, in that…”
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Author Correction: Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures by Ivanov, Vladimir N., Grabham, Peter W., Wu, Cheng-Chia, Hei, Tom K.

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Smurf2 inhibition enhances chemotherapy and radiation sensitivity in non-small-cell lung cancer by Chaudhary, Kunal R., Kinslow, Connor J., Cheng, Haiying, Silva, Jose M., Yu, Jiyang, Wang, Tony. J., Hei, Tom K., Halmos, Balazs, Cheng, Simon K.

“…Lung cancer has been the most common cancer worldwide for several decades. The outcomes of patients with locally advanced lung cancer remain dismal, and only a…”
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Gap Junction Communication and the Propagation of Bystander Effects Induced by Microbeam Irradiation in Human Fibroblast Cultures: The Impact of Radiation Quality by Autsavapromporn, Narongchai, Suzuki, Masao, Funayama, Tomoo, Usami, Noriko, Plante, Ianik, Yokota, Yuichiro, Mutou, Yasuko, Ikeda, Hiroko, Kobayashi, Katsumi, Kobayashi, Yasuhiko, Uchihori, Yukio, Hei, Tom K., Azzam, Edouard I., Murakami, Takeshi

“…Understanding the mechanisms underlying the bystander effects of low doses/low fluences of low- or high-linear energy transfer (LET) radiation is relevant to…”
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Microarray Profiling of TGF-β1-Induced Long Non-Coding RNA Expression Patterns in Human Lung Bronchial Epithelial BEAS-2B Cells by Hu, Wentao, Pei, Weiwei, Zhu, Lin, Nie, Jing, Pei, Hailong, Zhang, Jian, Li, Bingyan, Hei, Tom K., Zhou, Guangming

“…Background/Aims: TGF-β1 mediated radiation-induced bystander effects (RIBE) have been linked with malignant transformation and tumorigenesis. However, the…”
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Phytoestrogens and Breast Cancer Prevention: Possible Mechanisms of Action by Mense, Sarah M., Hei, Tom K., Ganju, Ramesh K., Bhat, Hari K.

“…Objective: Phytoestrogens display an array of pharmacologic properties, and in recent years investigation of their potential as anticancer agents has increased…”
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Funding for radiation research: past, present and future by Cho, Kunwoo, Imaoka, Tatsuhiko, Klokov, Dmitry, Paunesku, Tatjana, Salomaa, Sisko, Birschwilks, Mandy, Bouffler, Simon, Brooks, Antone L., Hei, Tom K., Iwasaki, Toshiyasu, Ono, Tetsuya, Sakai, Kazuo, Wojcik, Andrzej, Woloschak, Gayle E., Yamada, Yutaka, Hamada, Nobuyuki

“…For more than a century, ionizing radiation has been indispensable mainly in medicine and industry. Radiation research is a multidisciplinary field that…”
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The Tumorigenic Effect of lncRNA AFAP1‐AS1 is Mediated by Translated Peptide ATMLP Under the Control of m6A Methylation by Pei, Hailong, Dai, Yingchu, Yu, Yongduo, Tang, Jiaxin, Cao, Zhifei, Zhang, Yongsheng, Li, Bingyan, Nie, Jing, Hei, Tom K., Zhou, Guangming

“…Long noncoding RNAs (lncRNAs) in eukaryotic transcripts have long been believed to regulate various aspects of cellular processes, including carcinogenesis…”
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Ionizing radiation-induced long noncoding RNA CRYBG3 regulates YAP/TAZ through mechanotransduction by Zheng, Lijun, Luo, Chenyu, Yang, Nan, Pei, Hailong, Ji, Mintao, Shu, Yinyin, Zhang, Zhisen, Dong, Shuai, Wang, Xiuxiu, Li, Xuemei, Zhang, Wensheng, Wang, Yan, Li, Bingyan, Hei, Tom K., Zhou, Guangming, Chang, Lei

“…Mechanotransduction sensing of tissue architecture and cellular microenvironment is a fundamental regulator of cell fate, including cancer. Meanwhile, long…”
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RAC2-P38 MAPK-dependent NADPH oxidase activity is associated with the resistance of quiescent cells to ionizing radiation by Pei, Hailong, Zhang, Jian, Nie, Jing, Ding, Nan, Hu, Wentao, Hua, Junrui, Hirayama, Ryoichi, Furusawa, Yoshiya, Liu, Cuihua, Li, Bingyan, Hei, Tom K, Zhou, Guangming

“…Our recent study showed that quiescent G0 cells are more resistant to ionizing radiation than G1 cells; however, the underlying mechanism for this increased…”
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Single-Cell Transcriptome Analysis of Radiation Pneumonitis Mice by Yang, Miaomiao, Fan, Qiang, Hei, Tom K, Chen, Guodong, Cao, Wei, Meng, Gang, Han, Wei

“…Radiation-induced lung injury (RILI), especially radiation pneumonitis (RP), is a common clinical complication associated with thoracic radiotherapy for…”
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Androgen Receptor, Although Not a Specific Marker For, Is a Novel Target to Suppress Glioma Stem Cells as a Therapeutic Strategy for Glioblastoma by Zhao, Nan, Wang, Fei, Ahmed, Shaheen, Liu, Kan, Zhang, Chi, Cathcart, Sahara J., DiMaio, Dominick J., Punsoni, Michael, Guan, Bingjie, Zhou, Ping, Wang, Shuo, Batra, Surinder K., Bronich, Tatiana, Hei, Tom K., Lin, Chi

“…Targeting androgen receptor (AR) has been shown to be promising in treating glioblastoma (GBM) in cell culture and flank implant models but the mechanisms…”
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Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells by Xu, An, Chai, Yunfei, Nohmi, Takehiko, Hei, Tom K

“…Titanium dioxide (TiO2) nanoparticles and fullerene (C60) are two attractive manufactured nanoparticles with great promise in industrial and medical…”
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