Search Results - "Hegazy, Sahar K."

Study to compare the effect of casirivimab and imdevimab, remdesivir, and favipiravir on progression and multi-organ function of hospitalized COVID-19 patients by Hegazy, Sahar K., Tharwat, Samar, Hassan, Ahmed H.

“…Coronavirus disease 2019 (COVID-19) caused a progress in research to find a solution to this pandemic. Also, various advances in pharmacotherapy against…”
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Clinical study to compare the efficacy and safety of casirivimab & imdevimab, remdesivir, and favipravir in hospitalized COVID-19 patients by Hegazy, Sahar K., Tharwat, Samar, Hassan, Ahmed H.

“…•Corona Virus induced disease – 2019 (COVID-19) disaster motivates scientific research to find a settling to this pandemic.•Various advances in immunotherapy…”
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Pentoxifylline, a nonselective phosphodiesterase inhibitor, in adjunctive therapy in patients with irritable bowel syndrome treated with mebeverine by El‑Haggar, Sahar M., Hegazy, Sahar K., Abd-Elsalam, Sherief M., Bahaa, Mostafa M.

“…Irritable bowel syndrome (IBS) is a functional gastrointestinal condition marked by chronic bowel pain or discomfort, as well as changes in abdominal motility…”
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Retraction of “Study to compare the effect of casirivimab and imdevimab, remdesivir, and favipiravir on progression and multi-organ function of hospitalized COVID-19 patients” by Hegazy, Sahar K., Tharwat, Samar, Hassan, Ahmed H.

“…[This retracts the article DOI: 10.1515/med-2023-0768.]…”
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Antifibrotic effect of aloe vera in viral infection-induced hepatic periportal fibrosis by Hegazy, Sahar K, El-Bedewy, Mohamed, Yagi, Akira

“…AIM：To investigate the anti-oxidative and anti-fibrotic effects of aloe vera in patients with liver fibrosis.METHODS：Aloe vera high molecular weight…”
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Effect of probiotics on pro-inflammatory cytokines and NF-κB activation in ulcerative colitis by Hegazy, Sahar K

“…AIM: To demonstrate the therapeutic effect of probiotics in patients with ulcerative colitis (UC), and their effect on inflammatory mediators and nuclear…”
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Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer by Hegazy, Sahar K., El-Azab, Gamal A., Zakaria, Fatma, Mostafa, Mohamed F., El-Ghoneimy, Reham A.

“…Metastatic colorectal cancer (mCRC) predominantly contributes to cancer-related mortalities secondary to distant metastasis. This study aimed at investigating…”
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Repurposing metformin as adjuvant therapy in patients with ulcerative colitis treated with mesalamine: A randomized controlled double-blinded study by El‑Haggar, Sahar M., Hegazy, Sahar K., Maher, Maha M, Bahgat, Monir M, Bahaa, Mostafa M.

“…UC is triggered by various stimuli such as oxidative stress, antigens, immunity, and environmental factors. These stimuli release inflammatory cytokines such…”
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Repurposing celecoxib as adjuvant therapy in patients with Parkinsonian disease: a new therapeutic dawn: randomized controlled pilot study by Khrieba, Mohannad O., Hegazy, Sahar K., Mustafa, Wessam, El‑Haggar, Sahar M.

“…Background The clinical presentations of Parkinson’s disease (PD), a chronic neurodegenerative condition, include bradykinesia, hypokinesia, stiffness, resting…”
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Nigella sativa as a promising intervention for metabolic and inflammatory disorders in obese prediabetic subjects: A comparative study of Nigella sativa versus both lifestyle modification and metformin by Mostafa, Tarek M., Hegazy, Sahar K., Elnaidany, Sherin S., Shehabeldin, Walid A., Sawan, Eman S.

“…This study aimed at evaluating the effect of Nigella sativa (NS) on anthropometric, metabolic and inflammatory parameters and examining its related molecular…”
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Pentoxifylline in patients with ulcerative colitis treated with mesalamine by modulation of IL-6/STAT3, ZO-1, and S1P pathways: a randomized controlled double-blinded study by Bahaa, Mostafa M., Hegazy, Sahar K., Maher, Maha M., Bahgat, Monir M., El‑Haggar, Sahar M.

“…Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that lasts a long time and has a variety of causes. Aim The primary aim of this study…”
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Comparative randomized trial evaluating the effect of proton pump inhibitor versus histamine 2 receptor antagonist as an adjuvant therapy in diffuse large B-cell lymphoma by Hegazy, Sahar K., El-Haggar, Sahar M., Alhassanin, Suzan A., El-berri, Eman I.

“…The development of drug resistance remains the major obstacle to clinical efficacy of cancer chemotherapy. Consequently, finding new therapeutic options for…”
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Effect of genetic polymorphisms on the development of secondary failure to sulfonylurea in Egyptian patients with type 2 diabetes by El-sisi, Alaa E., Hegazy, Sahar K., Metwally, Shereen S., Wafa, Alaa M., Dawood, Naglaa A.

“…Objective: This study investigated the possibility that genetic factors, such as polymorphism of K inward rectifier subunit (Kir6.2), E23K, and Arg972…”
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Open‐label pilot study of ethosuximide as adjunctive therapy for relieving abdominal pain related to Irritable Bowel Syndrome by El‑Haggar, Sahar M., Hegazy, Sahar K., M. Abd‐Elsalam, Sherief, Bahaa, Mostafa M

“…What is known and objectives There is clear evidence for an association between irritable bowel syndrome (IBS) and visceral hypersensitivity. This clinical…”
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A Potential Role of Ethosuximide and Pentoxifylline in Relieving Abdominal Pain in Irritable Bowel Syndrome Patients Treated with Mebeverine: A Randomized, Double-Blind, Placebo-Controlled Trial by El-Haggar, Sahar M, Hegazy, Sahar K, Abd-Elsalam, Sherief M, Elkaeed, Eslam B, Al-Karmalawy, Ahmed A, Bahaa, Mostafa M

“…Irritable bowel syndrome (IBS) is defined as an association of chronic abdominal pain with bowel habit abnormalities, without clear organic dysfunction. T-type…”
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Effect of clarithromycin and fluconazole on the pharmacokinetics of montelukast in human volunteers by Hegazy, Sahar K., Mabrouk, Mokhtar M., Elsisi, Alaa E., Mansour, Noha O.

“…Objective Montelukast, a leukotriene receptor antagonist, is used in the treatment of asthma. The objective of the study reported here was to determine whether…”
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Alpha-lipoic acid improves subclinical left ventricular dysfunction in asymptomatic patients with type 1 diabetes by Hegazy, Sahar K, Tolba, Osama A, Mostafa, Tarek M, Eid, Manal A, El-Afify, Dalia R

“…Oxidative stress plays an important role in the development of diabetic cardiomyopathy. Alpha-lipoic acid (ALA) is a powerful antioxidant that may have a…”
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Evaluation of the anti-osteoporotic effects of metformin and sitagliptin in postmenopausal diabetic women by Hegazy, Sahar Kamal

“…Osteoporosis is the most important metabolic bone disease in patients with diabetes mellitus. Several studies have documented that metformin is osteogenic in…”
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EFFECT OF FENOFIBRATE ADJUVANT THERAPY ON ENDOTHELIAL DYSFUNCTION AND CARDIOVASCULAR RISK IN EGYPTIAN PATIENTS WITH TYPE 2 DIABETES MELLITUS by K HEGAZY, SAHAR, A ELBEDEWY, TAMER, M SAMI, HAIDY

“…Objective: Endothelial dysfunction is afflicted to the maturation of arteriosclerosis and type 2 diabetes mellitus (T2DM) vascular complications. This study…”
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A Potential Role of Ethosuximide and Pentoxifylline in Relieving Abdominal Pain in Irritable Bowel Syndrome Patients Treated with Mebeverine: A Randomized, Double-Blind, Placebo-Controlled Trial by El-Haggar, Sahar M, Hegazy, Sahar K, Abd-Elsalam, Sherief M, Elkaeed, Eslam B, Al-Karmalawy, Ahmed A, Bahaa, Mostafa M

“…Background and Purpose: Irritable bowel syndrome (IBS) is defined as an association of chronic abdominal pain with bowel habit abnormalities, without clear…”
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