Search Results - "Hegang Chen"

A randomized synbiotic trial to prevent sepsis among infants in rural India by Panigrahi, Pinaki, Parida, Sailajanandan, Nanda, Nimai C., Satpathy, Radhanath, Pradhan, Lingaraj, Chandel, Dinesh S., Baccaglini, Lorena, Mohapatra, Arjit, Mohapatra, Subhranshu S., Misra, Pravas R., Chaudhry, Rama, Chen, Hegang H., Johnson, Judith A., Morris, J. Glenn, Paneth, Nigel, Gewolb, Ira H.

“…Sepsis in early infancy results in one million annual deaths worldwide, most of them in developing countries. No efficient means of prevention is currently…”
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Tolerability, user acceptance and preference for a novel reusable respirator among health care workers by Zhuang, Eileen, Chen, Hegang H., Kolesnik, Olga, Hines, Stella E.

“…•CleanSpace Halo powered respirators have clear facemasks without belts or hoses.•Health care workers gave favorable tolerability scores to Halo…”
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Results of a randomized, double-blind, placebo-controlled trial of lorcaserin in cocaine use disorder by McCann, David J., Chen, Hegang H., Devine, Eric G., Gyaw, Shwe, Ramey, Tatiana

“…Cocaine use disorder (CUD) is a major public health problem for which there is no approved pharmacotherapy. The primary purpose of this study was to evaluate…”
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Diffusion Tensor Imaging Parameter Obtained during Acute Blunt Cervical Spinal Cord Injury in Predicting Long-Term Outcome by Shanmuganathan, Kathirkamanathan, Zhuo, Jaichen, Chen, Hegang H, Aarabi, Bizhan, Adams, Jason, Miller, Catriona, Menakar, Jay, Gullapalli, Rao P, Mirvis, Stuart E

“…There are no reliable neuroimaging biomarkers to predict long-term outcome after spinal cord injury. This prospective longitudinal study evaluates diffusion…”
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A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth by ZHIYONG GUO, XI YANG, KUNG, Hsing-Jien, BRODIE, Angela M. H, EDWARDS, Joanne, YUN QIU, FENG SUN, JIANG, Richeng, LINN, Douglas E, HEGE CHEN, HEGANG CHEN, XIANGTIAN KONG, MELAMED, Jonathan, TEPPER, Clifford G

“…The androgen receptor (AR) plays a key role in progression to incurable androgen ablation-resistant prostate cancer (PCA). We have identified three novel AR…”
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Utilizing ultra-early continuous physiologic data to develop automated measures of clinical severity in a traumatic brain injury population by Yang, Shiming, Hu, Peter, Kalpakis, Konstantinos, Burdette, Bradford, Chen, Hegang, Parikh, Gunjan, Felix, Ryan, Podell, Jamie, Badjatia, Neeraj

“…Determination of prognosis in the triage process after traumatic brain injury (TBI) is difficult to achieve. Current severity measures like the Trauma and…”
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Multiple sclerosis disease activity, a multi-biomarker score of disease activity and response to treatment in multiple sclerosis by Tatomir, Alexandru, Anselmo, Freidrich, Boodhoo, Dallas, Chen, Hegang, Mekala, Armugam P, Nguyen, Vinh, Cuevas, Jacob, Rus, Violeta, Rus, Horea

“…Regular assessment of disease activity in relapsing-remitting multiple sclerosis (RRMS) is required to optimize clinical outcomes. Biomarkers can be a valuable…”
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Characteristics Associated With Health Care Worker Knowledge and Confidence in Elastomeric Half-Mask Respirator Use by Thurman, Paul, Zhuang, Eileen, Chen, Hegang H., McClain, Caitlin, Sietsema, Margaret, Fernando, Rohan, McDiarmid, Melissa A., Hines, Stella E.

“…This study evaluated health care workers' (HCWs') knowledge and confidence in using elastomeric half-mask respirator (EHMR) attributes known to influence…”
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Rapid prediction of secondary neurologic decline after traumatic brain injury: a data analytic approach by Podell, Jamie, Yang, Shiming, Miller, Serenity, Felix, Ryan, Tripathi, Hemantkumar, Parikh, Gunjan, Miller, Catriona, Chen, Hegang, Kuo, Yi-Mei, Lin, Chien Yu, Hu, Peter, Badjatia, Neeraj

“…Secondary neurologic decline (ND) after traumatic brain injury (TBI) is independently associated with outcome, but robust predictors of ND are lacking. In this…”
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Replacement of Antiretroviral Therapy with HIV Broadly Neutralizing Antibodies to Maximize the Effectiveness of Chemotherapy in HIV Patients with Lung Cancer by Atkinson, Ben, Abassi, Abdolrahim, Sajadi, Mohammad M, Tehrani, Zahra Rikhtegaran, Le, Nhut M, Chen, Hegang H, Sausville, Edward, DeVico, Anthony L, Lewis, George K, Fan, Xiaoxuan, Heredia, Alonso

“…Non-small cell lung cancer (NSCLC) is the most fatal non-AIDS defining cancer in people living with HIV (PWH) on antiretroviral therapy (ART). Treatment of…”
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Regulation of Androgen Receptor Transcriptional Activity and Specificity by RNF6-Induced Ubiquitination by Xu, Kexin, Shimelis, Hermela, Linn, Douglas E., Jiang, Richeng, Yang, Xi, Sun, Feng, Guo, Zhiyong, Chen, Hege, Li, Wei, Chen, Hegang, Kong, Xiangtian, Melamed, Jonathan, Fang, Shengyun, Xiao, Zhen, Veenstra, Timothy D., Qiu, Yun

“…The androgen receptor (AR) plays a critical role in prostate cancer. We have identified a ubiquitin E3 ligase, RNF6, as an AR-associated protein in a proteomic…”
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A comparative analysis of ante- and postnatal clinical characteristics of extremely premature neonates suffering from refractory and non-refractory hypotension: Is early clinical differentiation possible? by Verma, Rita P., Dasnadi, Shaeequa, Zhao, Yuan, Chen, Hegang H.

“…About 25% of hypotensive ELBW infants are refractory to intravascular volume expansion and inotropic drugs (VI) and require hydrocortisone (HC). Such neonates…”
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Racial disparity in primary hepatocellular carcinoma : Tumor stage at presentation, surgical treatment and survival by SLOANE, Dana, HEGANG CHEN, HOWELL, Charles

“…The incidence and mortality rates from primary hepatocellular carcinoma (HCC) are higher in black Americans compared to whites. The goal of this study was to…”
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Cellular alterations in human traumatic brain injury: changes in mitochondrial morphology reflect regional levels of injury severity by Balan, Irina S, Saladino, Andrew J, Aarabi, Bizhan, Castellani, Rudolf J, Wade, Christine, Stein, Deborah M, Eisenberg, Howard M, Chen, Hegang H, Fiskum, Gary

“…Mitochondrial dysfunction may be central to the pathophysiology of traumatic brain injury (TBI) and often can be recognized cytologically by changes in…”
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The 44-kDa Pim-1 Kinase Phosphorylates BCRP/ABCG2 and Thereby Promotes Its Multimerization and Drug-resistant Activity in Human Prostate Cancer Cells by Xie, Yingqiu, Xu, Kexin, Linn, Douglas E., Yang, Xi, Guo, Zhiyong, Shimelis, Hermela, Nakanishi, Takeo, Ross, Douglas D., Chen, Hegang, Fazli, Ladan, Gleave, Martin E., Qiu, Yun

“…We previously showed that the 44-kDa serine/threonine kinase Pim-1 (Pim-1L) can protect prostate cancer cells from apoptosis induced by chemotherapeutic drugs…”
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Blunt splenic injury: use of a multidetector CT-based splenic injury grading system and clinical parameters for triage of patients at admission by Saksobhavivat, Nitima, Shanmuganathan, Kathirkamanathan, Chen, Hegang H, DuBose, Joseph J, Richard, Howard, Khan, Mansoor Ali, Menaker, Jay, Mirvis, Stuart E, Scalea, Thomas M

“…To assess the use of a dual-phase multidetector computed tomography (CT)-based grading system alone and in combination with assessment of clinical parameters…”
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Health Status of Adult Long-term Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study by Hudson, Melissa M, Mertens, Ann C, Yasui, Yutaka, Hobbie, Wendy, Chen, Hegang, Gurney, James G, Yeazel, Mark, Recklitis, Christopher J, Marina, Neyssa, Robison, Leslie R, Oeffinger, Kevin C, for the Childhood Cancer Survivor Study Investigators

“…CONTEXT Adult survivors of childhood cancer are at risk for medical and psychosocial sequelae that may adversely affect their health status. OBJECTIVES To…”
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Mechanistic insight of platelet apoptosis leading to non-surgical bleeding among heart failure patients supported by continuous-flow left ventricular assist devices by Mondal, Nandan K., Li, Tieluo, Chen, Zengsheng, Chen, Hegang H., Sorensen, Erik N., Pham, Si M., Sobieski, Michael A., Koenig, Steven C., Slaughter, Mark S., Griffith, Bartley P., Wu, Zhongjun J.

“…Non-surgical bleeding (NSB) is the most common clinical complication in heart failure (HF) patients supported by continuous-flow left ventricular assist…”
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Differential Regulation of Androgen Receptor by PIM-1 Kinases via Phosphorylation-dependent Recruitment of Distinct Ubiquitin E3 Ligases by Linn, Douglas E., Yang, Xi, Xie, Yingqiu, Alfano, Alan, Deshmukh, Dhanraj, Wang, Xin, Shimelis, Hermela, Chen, Hegang, Li, Wei, Xu, Kexin, Chen, Mingyuan, Qiu, Yun

“…Androgen receptor (AR) plays a pivotal role in prostate cancer. Regulation of AR transcriptional activity by post-translational modifications, such as…”
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Longitudinal assessment of glymphatic changes following mild traumatic brain injury: Insights from perivascular space burden and DTI-ALPS imaging by Zhuo, Jiachen, Raghavan, Prashant, Li, Jiang, Roys, Steven, Njonkou Tchoquessi, Rosy Linda, Chen, Hegang, Wickwire, Emerson M, Parikh, Gunjan Y, Schwartzbauer, Gary T, Grattan, Lynn M, Wang, Ze, Gullapalli, Rao P, Badjatia, Neeraj

“…Traumatic brain injury (TBI) even in the mild form may result in long-lasting post-concussion symptoms. TBI is also a known risk to late-life…”
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