Search Results - "Hefter, Dimitri"

APP as a Protective Factor in Acute Neuronal Insults by Hefter, Dimitri, Draguhn, Andreas

“…Despite its key role in the molecular pathology of Alzheimer's disease (AD), the physiological function of amyloid precursor protein (APP) is unknown…”
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Enriched Environment Modulates Sharp Wave-Ripple (SPW-R) Activity in Hippocampal Slices by Landeck, Lucie, Kaiser, Martin E, Hefter, Dimitri, Draguhn, Andreas, Both, Martin

“…Behavioral flexibility depends on neuronal plasticity which forms and adapts the central nervous system in an experience-dependent manner. Thus, plasticity…”
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Two Sides of the Same Coin: A Case Report of First-Episode Catatonic Syndrome in a High-Functioning Autism Patient by Hefter, Dimitri, Topor, Cristina E, Gass, Peter, Hirjak, Dusan

“…Catatonic phenomena such as stupor, mutism, stereotypy, echolalia, echopraxia, affective flattening, psychomotor deficits, and social withdrawal are…”
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Perinatal Hypoxia and Ischemia in Animal Models of Schizophrenia by Hefter, Dimitri, Marti, Hugo H, Gass, Peter, Inta, Dragos

“…Intrauterine or perinatal complications constitute a major risk for psychiatric diseases. Infants who suffered from hypoxia-ischemia (HI) are at twofold risk…”
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Rapid Support for Older Adults during the Initial Stages of the COVID-19 Pandemic: Results from a Geriatric Psychiatry Helpline by Wahl, Anna-Sophia, Benson, Gloria, Hausner, Lucrezia, Schmitt, Sandra, Knoll, Annika, Ferretti-Bondy, Adriana, Hefter, Dimitri, Froelich, Lutz

“…The COVID-19 pandemic and governmental lockdown measures disproportionally impact older adults. This study presents the results from a psychiatric helpline for…”
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Amyloid, APP, and Electrical Activity of the Brain by Hefter, Dimitri, Ludewig, Susann, Draguhn, Andreas, Korte, Martin

“…The Amyloid Precursor Protein (APP) is infamous for its proposed pivotal role in the pathogenesis of Alzheimer’s disease (AD). Much research on APP focusses on…”
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Mild metabolic stress is sufficient to disturb the formation of pyramidal cell ensembles during gamma oscillations by Elzoheiry, Shehabeldin, Lewen, Andrea, Schneider, Justus, Both, Martin, Hefter, Dimitri, Boffi, Juan Carlos, Hollnagel, Jan-Oliver, Kann, Oliver

“…Disturbances of cognitive functions occur rapidly during acute metabolic stress. However, the underlying mechanisms are not fully understood. Cortical gamma…”
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Molecular and cellular dissection of NMDA receptor subtypes as antidepressant targets by Lang, Elisabeth, Mallien, Anne S., Vasilescu, Andrei-Nicolae, Hefter, Dimitri, Luoni, Alessia, Riva, Marco A., Borgwardt, Stefan, Sprengel, Rolf, Lang, Undine E., Gass, Peter, Inta, Dragos

“…•Ketamine and other NMDAR modulators are effective alternative antidepressant drugs.•We review molecular domains of NMDAR implicated in mood…”
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Transient Oxygen-Glucose Deprivation Causes Region- and Cell Type-Dependent Functional Deficits in the Mouse Hippocampus In Vitro by Grube, Paul, Heuermann, Cedric, Rozov, Andrei, Both, Martin, Draguhn, Andreas, Hefter, Dimitri

“…Abstract Neurons are highly vulnerable to conditions of hypoxia-ischemia (HI) such as stroke or transient ischemic attacks. Recovery of cognitive and…”
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Altered prepulse inhibition of the acoustic startle response in BDNF-deficient mice in a model of early postnatal hypoxia: implications for schizophrenia by Lima-Ojeda, Juan M., Mallien, Anne S., Brandwein, Christiane, Lang, Undine E., Hefter, Dimitri, Inta, Dragos

“…The brain-derived neurotrophic factor (BDNF) is a major proliferative agent in the nervous system. Both BDNF-deficiency and perinatal hypoxia represent…”
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Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels by Hefter, Dimitri, Kaiser, Martin, Weyer, Sascha W, Papageorgiou, Ismini E, Both, Martin, Kann, Oliver, Müller, Ulrike C, Draguhn, Andreas

“…Acute cerebral ischemia and chronic neurovascular diseases share various common mechanisms with neurodegenerative diseases, such as disturbed cellular calcium…”
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