Search Results - "Heftdal, Line D."
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MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies
Published in Nature communications (05-06-2020)“…The MYC oncogene drives T- and B- lymphoid malignancies, including Burkitt’s lymphoma (BL) and Acute Lymphoblastic Leukemia (ALL). Here, we demonstrate a…”
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The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis
Published in Frontiers in immunology (25-09-2018)“…This review describes the IL-20 family of cytokines in rheumatoid arthritis (RA) and spondyloartrhitits (SpA) including psoriatic arthritis. The IL-20 receptor…”
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IL-12/IL-23p40 identified as a downstream target of apremilast in ex vivo models of arthritis
Published in Therapeutic advances in musculoskeletal disease (01-01-2019)“…Background: Apremilast (Otezla®) is a phosphodiesterase 4 (PDE4) inhibitor approved for the treatment of psoriasis and psoriatic arthritis (PsA), but the…”
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Abstract 126: MYC-driven lymphomas suppress NK surveillance by blocking maturation of early NK cells
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…The MYC oncogene is commonly overexpressed in hematopoietic cancers. In a transgenic mouse model of MYC-induced T-cell lymphoma, we found that there was a…”
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IL-12/IL-23p40 identified as a downstream target of apremilast in models of arthritis
Published in Therapeutic advances in musculoskeletal disease (01-02-2019)“…Background: Apremilast (Otezla ® ) is a phosphodiesterase 4 (PDE4) inhibitor approved for the treatment of psoriasis and psoriatic arthritis (PsA), but the…”
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