Search Results - "Heeschen, C"

Improvement of postnatal neovascularization by human adipose tissue-derived stem cells by Miranville, A, Heeschen, C, Sengenès, C, Curat, C A, Busse, R, Bouloumié, A

“…Several studies have suggested that stem cells are present in the stroma-vascular fraction (SVF) of adipose tissue (AT). To characterize the cell populations…”
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Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells by Urbich, Carmen, Aicher, Alexandra, Heeschen, Christopher, Dernbach, Elisabeth, Hofmann, Wolf K., Zeiher, Andreas M., Dimmeler, Stefanie

“…Circulating endothelial progenitor cells (EPC) are incorporated into newly formed capillaries, enhance neovascularization after hind limb ischemia and improve…”
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Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis by Huber, S., Bruns, C.J., Schmid, G., Hermann, P.C., Conrad, C., Niess, H., Huss, R., Graeb, C., Jauch, K.-W., Heeschen, C., Guba, M.

“…Lymphatic complications are common side effects of mammalian target of rapamycin (mTOR) inhibitor-based immunosuppression in kidney transplantation. Therefore,…”
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Switchable CAR-T cells mediate long-term remission of PDAC by Raj, D., Marshall, J., Young, T.S., Aicher, A., Heeschen, C.

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VAR2CSA-based CAR-T cells for the treatment of pancreatic ductal adenocarcinoma by Cutmore, L., Cornish, D., Brown, N., Nikolaidi, M., Raj, D., Heeschen, C., Marshall, J.

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αvβ6 targeted CAR-T cells in immunocompetent orthotopic murine PDAC by Brown, N., Nikolaidi, M., Cutmore, L., Cornish, D., Raj, D., Heeschen, C., Marshall, J.

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Autofluorescence as a new biomarker to identify glioblastoma stem cells by de Castro, J. Vieira, Miranda-Lorenzo, I, Cerqueira, M.T, Pinto, A.A, Heeschen, C, Costa, B.M

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Multimarker risk model containing troponin-T, interleukin 10, myeloperoxidase and placental growth factor predicts long-term cardiovascular risk after non-ST-segment elevation acute coronary syndrome by Oemrawsingh, R M, Lenderink, T, Akkerhuis, K M, Heeschen, C, Baldus, S, Fichtlscherer, S, Hamm, C W, Simoons, M L, Boersma, E

“…To evaluate the predictive value of seven biomarkers, which individually have been shown to be independent predictors, for use in a combined multimarker model…”
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The fuss over lipo"fuss"cin: not all autofluorescence is the same by Sainz, Jr, B, Miranda-Lorenzo, I, Heeschen, C

“…Since the first description of cellular autofluorescence over a century ago, we have now come to appreciate that autofluorescence should not be discarded as a…”
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ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation by Dumartin, L, Alrawashdeh, W, Trabulo, S M, Radon, T P, Steiger, K, Feakins, R M, di Magliano, M P, Heeschen, C, Esposito, I, Lemoine, N R, Crnogorac-Jurcevic, T

“…The mechanisms of initiation of pancreatic ductal adenocarcinoma (PDAC) are still largely unknown. In the present study, we analysed the role of anterior…”
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Platelet glycoprotein IIb/IIIa inhibition in acute coronary syndromes. Gradient of benefit related to the revascularization strategy by Roffi, M., Chew, D.P., Mukherjee, D., Bhatt, D.L., White, J.A., Moliterno, D.J., Heeschen, C., Hamm, C.W., Robbins, M.A., Kleiman, N.S., Théroux, P., White, H.D., Topol, E.J.

“…Aims To assess the efficacy of platelet glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes primarily medically managed. Methods and…”
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Elevated placental growth factor levels are associated with adverse outcomes at 4-year followup in patients with acute coronary syndrome by Lenderink, T, Heeschen, C, Fichtlscherer, S

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Elevated troponin T and C-reactive protein predict impaired outcome for 4 years in patients with refractory unstable angina, and troponin T predicts benefit of treatment with abciximab in combination with PTCA by Lenderink, T, Boersma, E, Heeschen, C, Vahanian, A, de Boer, M.-J, Umans, V, van den Brand, M.J.B.M, Hamm, C.W, Simoons, M.L

“…Aims Treatment with the glycoprotein IIb/IIIa receptor antagonist abciximab before and during coronary intervention in refractory unstable angina improves…”
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ADMA regulates angiogenesis: genetic and metabolic evidence by Achan, V, Ho, HK, Heeschen, C, Stuehlinger, M, Jang, JJ, Kimoto, M, Vallance, P, Cooke, JP

“…Endothelium-derived nitric oxide (NO) plays an important role in transducing the effects of angiogenic factors. Asymmetric dimethylarginine (ADMA) is an…”
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Cardiovascular risk and therapeutic benefit of coronary interventions for patients with unstable angina according to the troponin T status by Heeschen, C., Goldmann, B.U., Terres, W., Hamm, C.W.

“…Aims Elevation of troponin T in patients with unstable angina is predictive of adverse outcomes. Since no advanced therapeutic concept for such high-risk…”
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Correlation of molecular profiles with response to targeted drugs in pancreatic cancer models by Behrens, D., Lawlor, R., Heeschen, C., Buettner, B., Siveke, J., Hoffmann, J.

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Pancreatic cancer stem cell proliferation is strongly inhibited by diethyldithiocarbamate-copper complex loaded into hyaluronic acid decorated liposomes by Marengo, Alessandro, Forciniti, Stefania, Dando, Ilaria, Dalla Pozza, Elisa, Stella, Barbara, Tsapis, Nicolas, Yagoubi, Najet, Fanelli, Giuseppina, Fattal, Elias, Heeschen, Christopher, Palmieri, Marta, Arpicco, Silvia

“…Pancreatic cancer stem cells (CSCs) are responsible for resistance to standard therapy, metastatic potential, and disease relapse following treatments. The…”
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Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy by Lonardo, Enza, Hermann, Patrick C., Mueller, Maria-Theresa, Huber, Stephan, Balic, Anamaria, Miranda-Lorenzo, Irene, Zagorac, Sladjana, Alcala, Sonia, Rodriguez-Arabaolaza, Iker, Ramirez, Juan Carlos, Torres-Ruíz, Raul, Garcia, Elena, Hidalgo, Manuel, Cebrián, David Álvaro, Heuchel, Rainer, Löhr, Matthias, Berger, Frank, Bartenstein, Peter, Aicher, Alexandra, Heeschen, Christopher

“…Nodal and Activin belong to the TGF-β superfamily and are important regulators of embryonic stem cell fate. Here we investigated whether Nodal and Activin…”
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Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells by Dimmeler, Stefanie, Aicher, Alexandra, Heeschen, Christopher, Mildner-Rihm, Christiane, Urbich, Carmen, Ihling, Christian, Technau-Ihling, Katja, Zeiher, Andreas M

“…Endothelial nitric oxide synthase (eNOS) is essential for neovascularization. Here we show that the impaired neovascularization in mice lacking eNOS is related…”
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Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease by HEESCHEN, Christopher, LEHMANN, Ralf, HONOLD, Jörg, ASSMUS, Birgit, AICHER, Alexandra, WALTER, Dirk H, MARTIN, Hans, ZEIHER, Andreas M, DIMMELER, Stefanie

“…Cell therapy with bone marrow-derived stem/progenitor cells is a novel option for improving neovascularization and cardiac function in ischemic heart disease…”
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