Search Results - "Heerspink, HJ Lambers"
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Prediction of the effect of atrasentan on renal and heart failure outcomes based on short-term changes in multiple risk markers
Published in European journal of preventive cardiology (01-05-2016)“…Background A recent phase II clinical trial (Reducing Residual Albuminuria in Subjects with Diabetes and Nephropathy with AtRasentan trial and an identical…”
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Predictors of mortality in hospital survivors with type 2 diabetes mellitus and acute coronary syndromes
Published in Diabetes & vascular disease research (01-01-2018)“…To define the predictors of long-term mortality in patients with type 2 diabetes mellitus and recent acute coronary syndrome. A total of 7226 patients from a…”
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Modeling and simulation for medical product development and evaluation: highlights from the FDA-C-Path-ISOP 2013 workshop
Published in Journal of pharmacokinetics and pharmacodynamics (01-12-2014)“…Medical-product development has become increasingly challenging and resource-intensive. In 2004, the Food and Drug Administration (FDA) described critical…”
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Dual RAS therapy not on target, but fully alive
Published in Nephron. Clinical practice (01-09-2010)“…Inhibitors of the renin-angiotensin system (RAS) form a cornerstone in the treatment of kidney disease. These drugs lower blood pressure and albuminuria, and…”
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A prediction of the renal and cardiovascular efficacy of aliskiren in ALTITUDE using short-term changes in multiple risk markers
Published in European journal of preventive cardiology (01-04-2014)“…Introduction We recently developed and validated in existing trials a novel algorithm (PRE score) to predict long-term drug efficacy based on short-term…”
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