Search Results - "Heermann, Ralf"
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Specificity of Signal-Binding via Non-AHL LuxR-Type Receptors
Published in PloS one (29-04-2015)“…Quorum sensing is a typical communication system among Gram-negative bacteria used to control group-coordinated behavior via small diffusible molecules…”
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A Sensory Complex Consisting of an ATP-binding Cassette Transporter and a Two-component Regulatory System Controls Bacitracin Resistance in Bacillus subtilis
Published in The Journal of biological chemistry (03-10-2014)“…Resistance against antimicrobial peptides in many Firmicutes bacteria is mediated by detoxification systems that are composed of a two-component regulatory…”
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3
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice
Published in Blood (17-11-2016)“…Deep venous thrombosis (DVT) is one of the most common cardiovascular diseases, but its pathophysiology remains incompletely understood. Although sterile…”
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A signaling complex of adenylate cyclase CyaC of Sinorhizobium meliloti with cAMP and the transcriptional regulators Clr and CycR
Published in BMC microbiology (26-08-2023)“…Abstract Background Adenylate cyclases (ACs) generate the second messenger cyclic AMP (cAMP), which is found in all domains of life and is involved in the…”
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Dialkylresorcinols as bacterial signaling molecules
Published in Proceedings of the National Academy of Sciences - PNAS (13-01-2015)“…It is well recognized that bacteria communicate via small diffusible molecules, a process termed quorum sensing. The best understood quorum sensing systems are…”
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Two novel XRE-like transcriptional regulators control phenotypic heterogeneity in Photorhabdus luminescens cell populations
Published in BMC microbiology (25-02-2021)“…The insect pathogenic bacterium Photorhabdus luminescens exists in two phenotypically different forms, designated as primary (1°) and secondary (2°) cells…”
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The great potential of entomopathogenic bacteria Xenorhabdus and Photorhabdus for mosquito control: a review
Published in Parasites & vectors (29-07-2020)“…The control of insects of medical importance, such as Aedes aegypti and Aedes albopictus are still the only effective way to prevent the transmission of…”
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High-throughput synthesis of CeO2 nanoparticles for transparent nanocomposites repelling Pseudomonas aeruginosa biofilms
Published in Scientific reports (10-03-2022)“…Preventing bacteria from adhering to material surfaces is an important technical problem and a major cause of infection. One of nature’s defense strategies…”
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A novel tool for stable genomic reporter gene integration to analyze heterogeneity in Photorhabdus luminescens at the single-cell level
Published in BioTechniques (01-08-2015)“…Determination of reporter gene activity at the single-cell level is a prerequisite for analyzing heterogeneous gene expression in bacteria. The insect…”
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Characterization of the pleiotropic LysR-type transcription regulator LeuO of Escherichia coli
Published in Nucleic acids research (22-08-2019)“…Abstract LeuO is a pleiotropic LysR-type transcriptional regulator (LTTR) and co-regulator of the abundant nucleoid-associated repressor protein H-NS in…”
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A Dual-Sensing Receptor Confers Robust Cellular Homeostasis
Published in Cell reports (Cambridge) (28-06-2016)“…Cells have evolved diverse mechanisms that maintain intracellular homeostasis in fluctuating environments. In bacteria, control is often exerted by…”
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Phenotypic and genomic comparison of Photorhabdus luminescens subsp. laumondii TT01 and a widely used rifampicin-resistant Photorhabdus luminescens laboratory strain
Published in BMC genomics (29-11-2018)“…Photorhabdus luminescens is an enteric bacterium, which lives in mutualistic association with soil nematodes and is highly pathogenic for a broad spectrum of…”
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Purification, Reconstitution, and Characterization of the CpxRAP Envelope Stress System of Escherichia coli
Published in The Journal of biological chemistry (23-03-2007)“…In Escherichia coli the Cpx sensor regulator system senses different kinds of envelope stress and responds by triggering the expression of periplasmic folding…”
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Hierarchic regulation of a metabolic pathway: H-NS, CRP, and SsrB control myo -inositol utilization by Salmonella enterica
Published in Microbiology spectrum (11-01-2024)“…The capacity to utilize myo-inositol (MI) as sole carbon and energy source is widespread among bacteria, among them the intestinal pathogen . Typhimurium. This…”
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High-throughput sequencing analysis reveals genomic similarity in phenotypic heterogeneous Photorhabdus luminescens cell populations
Published in Annals of microbiology (25-05-2022)“…Abstract Purpose Phenotypic heterogeneity occurs in many bacterial populations: single cells of the same species display different phenotypes, despite being…”
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Deciphering the Rules Underlying Xenogeneic Silencing and Counter-Silencing of Lsr2-like Proteins Using CgpS of Corynebacterium glutamicum as a Model
Published in mBio (04-02-2020)“…Lsr2-like nucleoid-associated proteins play an important role as xenogeneic silencers (XS) of horizontally acquired genomic regions in actinobacteria. In this…”
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Interaction Analysis of a Two-Component System Using Nanodiscs
Published in PloS one (16-02-2016)“…Two-component systems are the major means by which bacteria couple adaptation to environmental changes. All utilize a phosphorylation cascade from a histidine…”
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HexA is a versatile regulator involved in the control of phenotypic heterogeneity of Photorhabdus luminescens
Published in PloS one (27-04-2017)“…Phenotypic heterogeneity in microbial communities enables genetically identical organisms to behave differently even under the same environmental conditions…”
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The Type VI secretion systems of the insect pathogen Photorhabdus luminescens are involved in interbacterial competition, motility and secondary metabolism
Published in The Microbe (01-06-2024)“…The Type VI Secretion System (T6SS) is used as weapon by a variety of Gram-negative bacteria in polymicrobial niche competition. Its characterization and study…”
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Interkingdom Signaling of the Insect Pathogen Photorhabdus luminescens with Plants Via the LuxR solo SdiA
Published in Microorganisms (Basel) (30-03-2023)“…In bacteria, group-coordinated behavior such as biofilm formation or virulence are often mediated via cell-cell communication, a process referred to as quorum…”
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