Search Results - "Heeren, R.M.A."

P.1.i.056 Mass spectrometry imaging as a powerful tool for detailed molecular investigation of brain pathologies: molecular microscope for peroxisomal disorders by Skraskova, K, Khmelinskii, A, Abdelmoula, W.M, De Munter, S, Baes, M, Heeren, R.M.A

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In-situ lipid alterations of aortic atherosclerosis in LDLR-deficient mice using mass spectrometry imaging by Martin-Lorenzo, M., Cao, J., Van Kuijk, K., Gijbels, M.J., Claes, B.S.R., Heeren, R.M.A., Sluimer, J., Alvarez-Llamas, G., Balluff, B.

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Class-specific depletion of lipid ion signals in tissues upon formalin fixation by Vos, D.R.N., Bowman, A.P., Heeren, R.M.A., Balluff, B., Ellis, S.R.

“…Formalin fixation (FF) is widely used in pathology labs due to its ability to prevent tissue degradation and better preserve tissue morphology, thereby…”
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Ion mobility spectrometry reveals intermediate states in temperature-resolved DNA unfolding by Hommersom, B., Porta, T., Heeren, R.M.A.

“…[Display omitted] •Stable intermediate DNA unfolding states revealed.•Solution phase unfolding of double stranded DNA followed with ion mobility…”
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Identification of a distinct lipidomic profile in the osteoarthritic synovial membrane by mass spectrometry imaging by Rocha, B., Cillero-Pastor, B., Ruiz-Romero, C., Paine, M.R.L., Cañete, J.D., Heeren, R.M.A., Blanco, F.J.

“…Synovial inflammation is one of the most characteristic events in different types of arthritis, including Osteoarthritis (OA). Emerging evidence also suggests…”
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Three-Dimensional Mass Spectrometry Imaging Of Lipids In Mouse Aortic Atherosclerotic Plaque by Cao, J., Goossens, P., Martin-Lorenzo, M., Ščupáková, K., Dewez, F., Biessen, E.A.L., Heeren, R.M.A., Balluff, B.

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FRI-227 - Cross-species molecular imaging of bile salts and lipids: Identification of hydroxyl-sulfatides as marker of bile ducts by Flinders, B., Huizing, L., van Heerden, M., Cuyckens, F., Olde Damink, S., Heeren, R.M.A., Schaap, F., Vreeken, R.

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Cross-species molecular imaging of bile salts and lipids: Identification of hydroxyl-sulfatides as marker of bile ducts by Flinders, B., Huizing, L., van Heerden, M., Cuyckens, F., Olde Damink, S., Heeren, R.M.A., Schaap, F., Vreeken, R.

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FRI-460 - Spatial systems lipidomics reveals nonalcoholic fatty liver disease heterogeneity by Scupakova, K., Soons, Z., Ertaylan, G., Pierzchalski, K.A., Eijkel, G.B., Ellis, S.R., Greve, J.W., Driessen, A., De Kok, T.M., Rensen, S., Damink, S.O., Heeren, R.M.A.

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Spatial systems lipidomics reveals nonalcoholic fatty liver disease heterogeneity by Scupakova, K., Soons, Z., Ertaylan, G., Pierzchalski, K.A., Eijkel, G.B., Ellis, S.R., Greve, J.W., Driessen, A., De Kok, T.M., Rensen, S., Damink, S.O., Heeren, R.M.A.

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Spatial multiomics show lipid metabolism alterations in prostate cancer by Andersen, M.K., Midtbust, E., Krossa, S., Viset, T., Størkersen, Ø., Vandenbosch, M., Claes, B., Giampà, M., Høiem, T.S., Heeren, R.M.A., Giskeødegård, G.F., Rye, M.B., Tessem, M-B.

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P10 - Spatial multiomics show lipid metabolism alterations in prostate cancer by Andersen, M.K., Midtbust, E., Krossa, S., Viset, T., Størkersen, Ø., Vandenbosch, M., Claes, B., Giampà, M., Høiem, T.S., Heeren, R.M.A., Giskeødegård, G.F., Rye, M.B., Tessem, M-B.

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Spatially resolved proteomics in osteoarthritis: State of the art and new perspectives by Eveque-Mourroux, M.R., Rocha, B., Barré, F.P.Y., Heeren, R.M.A., Cillero-Pastor, B.

“…Osteoarthritis (OA) is one of the most common diseases worldwide caused by chronic degeneration of the joints. Its high prevalence and the involvement of…”
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Strategies for managing multi-patient 3D mass spectrometry imaging data by Vos, D.R.N., Jansen, I., Lucas, M., Paine, M.R.L., de Boer, O.J., Meijer, S.L., Savci-Heijink, C.D., Marquering, H.A., de Bruin, D.M., Heeren, R.M.A., Ellis, S.R., Balluff, B.

“…Mass spectrometry imaging (MSI) has emerged as a powerful tool in biomedical research to reveal the localization of a broad scale of compounds ranging from…”
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A modular data and control system to improve sensitivity, selectivity, speed of analysis, ease of use, and transient duration in an external source FTICR-MS by Mize, T.H, Taban, I, Duursma, M, Seynen, M, Konijnenburg, M, Vijftigschild, A, Doornik, C.V, Rooij, G.V, Heeren, R.M.A

“…We present here a new Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS) controller designed and constructed to meet the growing need for…”
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Why don’t biologists use SIMS? by Heeren, R.M.A., McDonnell, L.A., Amstalden, E., Luxembourg, S.L., Altelaar, A.F.M., Piersma, S.R.

“…Secondary ion mass spectrometry is commonly used to study many different types of complex surfaces. Yet, compared with MALDI and ESI–MS, SIMS has not made a…”
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Parallel Processing of Large Datasets from NanoLC-FTICR-MS Measurements by van der Burgt, Y.E.M., Taban, I.M., Konijnenburg, M., Biskup, M., Duursma, M.C., Heeren, R.M.A., Römpp, A., van Nieuwpoort, R.V., Bal, H.E.

“…A new approach for automatic parallel processing of large mass spectral datasets in a distributed computing environment is demonstrated to significantly…”
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P37 - Simultaneous detection of the cancer biomarkers zinc and citrate in prostate cancer tissue using mass spectrometry imaging by Andersen, M.K., Krossa, S., Høiem, T.S., Bucholz, R., Claes, B.S.R., Balluff, B., Ellis, S., Richardsen, E., Bertillsson, H., Heeren, R.M.A., Bathen, T.F., Karst, U., Giskeødegård, G.F., Tessem, M.

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Simultaneous detection of the cancer biomarkers zinc and citrate in prostate cancer tissue using mass spectrometry imaging by Andersen, M.K., Krossa, S., Høiem, T.S., Bucholz, R., Claes, B.S.R., Balluff, B., Ellis, S., Richardsen, E., Bertillsson, H., Heeren, R.M.A., Bathen, T.F., Karst, U., Giskeødegård, G.F., Tessem, M.

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Controlled laser cleaning of painted artworks using accurate beam manipulation and on-line LIBS-detection by Scholten, J.H, Teule, J.M, Zafiropulos, V, Heeren, R.M.A

“…An innovative laser restoration tool for non-contact cleaning of painted artworks is developed. Accurate beam manipulation techniques in combination with…”
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