Changes in electrocorticographic beta frequency components precede spreading depolarization in patients with acute brain injury

Highlights • Association between increased SD count and reduced beta frequency was found. • Ketamine increased relative beta frequency band power and reduced SDs. • Prospective analysis of beta frequency band alteration might help to predict occurrence of SDs in future studies.

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Bibliographic Details
Published in:	Clinical neurophysiology Vol. 127; no. 7; pp. 2661 - 2667
Main Authors:	Hertle, Daniel N, Heer, Marina, Santos, Edgar, Schöll, Michael, Kowoll, Christina M, Dohmen, Christian, Diedler, Jennifer, Veltkamp, Roland, Graf, Rudolf, Unterberg, Andreas W, Sakowitz, Oliver W
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ireland Ltd 01-07-2016
Subjects:	Analgesics - administration & dosage Analgesics - adverse effects Analgesics - therapeutic use Beta frequency Beta Rhythm Brain Injuries - diagnosis Brain Injuries - drug therapy Brain Injuries - physiopathology EEG Female Humans Hypnotics and Sedatives - administration & dosage Hypnotics and Sedatives - adverse effects Hypnotics and Sedatives - therapeutic use Ketamine Ketamine - administration & dosage Ketamine - adverse effects Ketamine - therapeutic use Male Middle Aged Neurology Spreading depolarization Ketamine Beta frequency Spreading depolarization EEG
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Summary:	Highlights • Association between increased SD count and reduced beta frequency was found. • Ketamine increased relative beta frequency band power and reduced SDs. • Prospective analysis of beta frequency band alteration might help to predict occurrence of SDs in future studies.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Undefined-2
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2016.04.026