Search Results - "Heeger, Sebastian"

Condensin, Chromatin Crossbarring and Chromosome Condensation by Thadani, Rahul, Uhlmann, Frank, Heeger, Sebastian

“…The processes underlying the large-scale reorganisation of chromatin in mitosis that form compact mitotic chromosomes and ensure the fidelity of chromosome…”
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Eco1-Dependent Cohesin Acetylation During Establishment of Sister Chromatid Cohesion by Ben-Shahar, Tom Rolef, Heeger, Sebastian, Lehane, Chris, East, Philip, Flynn, Helen, Skehel, Mark, Uhlmann, Frank

“…Replicated chromosomes are held together by the chromosomal cohesin complex from the time of their synthesis in S phase onward. This requires the replication…”
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Cell-Cycle Regulation of Dynamic Chromosome Association of the Condensin Complex by Thadani, Rahul, Kamenz, Julia, Heeger, Sebastian, Muñoz, Sofía, Uhlmann, Frank

“…Eukaryotic cells inherit their genomes in the form of chromosomes, which are formed from the compaction of interphase chromatin by the condensin complex…”
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A simple biophysical model emulates budding yeast chromosome condensation by Cheng, Tammy M K, Heeger, Sebastian, Chaleil, Raphaël A G, Matthews, Nik, Stewart, Aengus, Wright, Jon, Lim, Carmay, Bates, Paul A, Uhlmann, Frank

“…Mitotic chromosomes were one of the first cell biological structures to be described, yet their molecular architecture remains poorly understood. We have…”
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Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes by Schittenhelm, Ralf B, Heeger, Sebastian, Althoff, Friederike, Walter, Anne, Heidmann, Stefan, Mechtler, Karl, Lehner, Christian F

“…Chromosome segregation during meiosis and mitosis depends on the assembly of functional kinetochores within centromeric regions. Centromeric DNA and…”
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Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog by Heeger, Sebastian, Leismann, Oliver, Schittenhelm, Ralf, Schraidt, Oliver, Heidmann, Stefan, Lehner, Christian F

“…Faithful transmission of genetic information during mitotic divisions depends on bipolar attachment of sister kinetochores to the mitotic spindle and on…”
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Rapid effects of acute anoxia on spindle kinetochore interactions activate the mitotic spindle checkpoint by Pandey, Rahul, Heeger, Sebastian, Lehner, Christian F

“…The dramatic chromosome instability in certain tumors might reflect a synergy of spindle checkpoint defects with hypoxic conditions. In Caenorhabditis elegans…”
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The Mitotic Arrest in Response to Hypoxia and of Polar Bodies during Early Embryogenesis Requires Drosophila Mps1 by Fischer, Matthias G., Heeger, Sebastian, Häcker, Udo, Lehner, Christian F.

“…Mps1 kinase plays an evolutionary conserved role in the mitotic spindle checkpoint [1–8]. This system precludes anaphase onset until all chromosomes have…”
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