Search Results - "Hee Won Yang"

The structural changes of a local tourism network: comparison of before and after COVID-19 by Jeon, Chang-Young, Yang, Hee-Won

“…The COVID-19 pandemic has caused dramatic changes on a global scale. According to the United Nations World Tourism Organization (2020), the restricted movement…”
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Cooperative Activation of PI3K by Ras and Rho Family Small GTPases by Yang, Hee Won, Shin, Min-Gyoung, Lee, Sangkyu, Kim, Jeong-Rae, Park, Wei Sun, Cho, Kwang-Hyun, Meyer, Tobias, Do Heo, Won

“…Phosphoinositide 3-kinases (PI3Ks) and Ras and Rho family small GTPases are key regulators of cell polarization, motility, and chemotaxis. They influence each…”
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What drives tourists to take a digital‐free tourism? by Liu, Jia‐Qi, Jeon, Chang‐Young, Yang, Hee‐Won

“…This study utilizes a combined model of two social cognitive models, protection motivation theory and theory of planned behavior, to analyze how smartphone use…”
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1.2-GHz repetition rate, diode-pumped femtosecond Yb:KYW laser mode-locked by a carbon nanotube saturable absorber mirror by Yang, Hee-Won, Kim, Chur, Choi, Sun Young, Kim, Guang-Hoon, Kobayashi, Yohei, Rotermund, Fabian, Kim, Jungwon

“…We demonstrate a 1.2-GHz repetition rate, diode-pumped, self-starting, 168-fs (FWHM) pulsewidth Yb:KYW laser mode-locked by a carbon nanotube (CNT) saturable…”
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Interannual variation of the southern limit in the Yellow Sea Bottom Cold Water and its causes by Yang, Hee-Won, Cho, Yang-Ki, Seo, Gwang-Ho, You, Sung Hyup, Seo, Jang-Won

“…The Yellow Sea Bottom Cold Water (YSBCW) occupies a wide region below the Yellow Sea (YS) thermocline in summer. The southern limit of the YSBCW shows…”
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CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition by Kim, Sungsoo, Leong, Alessandra, Kim, Minah, Yang, Hee Won

“…External signaling controls cell-cycle entry until cells irreversibly commit to the cell cycle to ensure faithful DNA replication. This process is tightly…”
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Non-canonical pathway for Rb inactivation and external signaling coordinate cell-cycle entry without CDK4/6 activity by Zhang, Mimi, Kim, Sungsoo, Yang, Hee Won

“…Cyclin-dependent kinases 4 and 6 (CDK4/6) are critical for initiating cell proliferation by inactivating the retinoblastoma (Rb) protein. However, mammalian…”
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Locally excitable Cdc42 signals steer cells during chemotaxis by Yang, Hee Won, Collins, Sean R., Meyer, Tobias

“…Neutrophils and other amoeboid cells chemotax by steering their front ends towards chemoattractant. Although Ras, Rac, Cdc42 and RhoA small GTPases all…”
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Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells by Hayer, Arnold, Shao, Lin, Chung, Mingyu, Joubert, Lydia-Marie, Yang, Hee Won, Tsai, Feng-Chiao, Bisaria, Anjali, Betzig, Eric, Meyer, Tobias

“…The development and maintenance of tissues requires collective cell movement, during which neighbouring cells coordinate the polarity of their migration…”
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Outcome Differences by Delirium Motor Subtype in Patients with Ischemic Stroke by Hee Won Yang, Miji Lee, Jong Wook Shin, Hye Seon Jeong, Jei Kim, Jeong Lan Kim

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Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1 by Chung, Mingyu, Liu, Chad, Yang, Hee Won, Köberlin, Marielle S., Cappell, Steven D., Meyer, Tobias

“…Cells escape the need for mitogens at a restriction point several hours before entering S phase. The restriction point has been proposed to result from CDK4/6…”
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Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation by Kim, Minah, Allen, Breanna, Korhonen, Emilia A, Nitschké, Maximilian, Yang, Hee Won, Baluk, Peter, Saharinen, Pipsa, Alitalo, Kari, Daly, Christopher, Thurston, Gavin, McDonald, Donald M

“…Angiopoietin-2 (ANG2) regulates blood vessel remodeling in many pathological conditions through differential effects on Tie2 signaling. While ANG2 competes…”
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The Impact of the COVID-19 Pandemic on Tourists' WTP: Using the Contingent Valuation Method by Jeon, Chang-Young, Yang, Hee-Won

“…This study estimated tourists' willingness to pay (WTP) for tourist sites or facilities in the prolonged COVID-19 pandemic by applying the dichotomous…”
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Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma by Nguyen, Trang T. T., Shang, Enyuan, Shu, Chang, Kim, Sungsoo, Mela, Angeliki, Humala, Nelson, Mahajan, Aayushi, Yang, Hee Won, Akman, Hasan Orhan, Quinzii, Catarina M., Zhang, Guoan, Westhoff, Mike-Andrew, Karpel-Massler, Georg, Bruce, Jeffrey N., Canoll, Peter, Siegelin, Markus D.

“…Aurora kinase A (AURKA) has emerged as a drug target for glioblastoma (GBM). However, resistance to therapy remains a critical issue. By integration of…”
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Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity by Liu, Chad, Konagaya, Yumi, Chung, Mingyu, Daigh, Leighton H., Fan, Yilin, Yang, Hee Won, Terai, Kenta, Matsuda, Michiyuki, Meyer, Tobias

“…Cell-cycle entry relies on an orderly progression of signaling events. To start, cells first activate the kinase cyclin D-CDK4/6, which leads to eventual…”
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Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation by Yang, Hee Won, Cappell, Steven D, Jaimovich, Ariel, Liu, Chad, Chung, Mingyu, Daigh, Leighton H, Pack, Lindsey R, Fan, Yilin, Regot, Sergi, Covert, Markus, Meyer, Tobias

“…Mammalian cells typically start the cell-cycle entry program by activating cyclin-dependent protein kinase 4/6 (CDK4/6). CDK4/6 activity is clinically relevant…”
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Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization by Tsai, Tony Y.-C., Collins, Sean R., Chan, Caleb K., Hadjitheodorou, Amalia, Lam, Pui-Ying, Lou, Sunny S., Yang, Hee Won, Jorgensen, Julianne, Ellett, Felix, Irimia, Daniel, Davidson, Michael W., Fischer, Robert S., Huttenlocher, Anna, Meyer, Tobias, Ferrell, James E., Theriot, Julie A.

“…Efficient chemotaxis requires rapid coordination between different parts of the cell in response to changing directional cues. Here, we investigate the…”
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Angiopoietin-2 blockade suppresses growth of liver metastases from pancreatic neuroendocrine tumors by promoting T cell recruitment by Lee, Eunhyeong, O'Keefe, Sophie, Leong, Alessandra, Park, Ha-Ram, Varadarajan, Janani, Chowdhury, Subrata, Hiner, Shannon, Kim, Sungsoo, Shiva, Anahita, Friedman, Richard A, Remotti, Helen, Fojo, Tito, Yang, Hee Won, Thurston, Gavin, Kim, Minah

“…Improving the management of metastasis in pancreatic neuroendocrine tumors (PanNETs) is critical, as nearly half of patients with PanNETs present with liver…”
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Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer by Kim, Sungsoo, Armand, Jessica, Safonov, Anton, Zhang, Mimi, Soni, Rajesh K., Schwartz, Gary, McGuinness, Julia E., Hibshoosh, Hanina, Razavi, Pedram, Kim, Minah, Chandarlapaty, Sarat, Yang, Hee Won

“…Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) are key therapeutic agents in the management of metastatic hormone-receptor-positive breast cancer…”
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Association between serum free hemoglobin level and cerebral white matter hyperintensity volume in older adults by Oh, Dae Jong, Kim, Jun Sung, Lee, Subin, Yang, Hee Won, Bae, Jong Bin, Han, Ji Won, Kim, Ki Woong

“…The association between serum free hemoglobin (sfHb) level and white matter hyperintensity (WMH) volume is controversial. This study is to examine this…”
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