Search Results - "Hee Kwon, Joo"
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Pyrrole-Containing Alkaloids from a Marine-Derived Actinobacterium Streptomyces zhaozhouensis and Their Antimicrobial and Cytotoxic Activities
Published in Marine drugs (06-03-2023)“…Two new alkaloids, streptopyrroles B and C ( and ), were discovered through a chemical investigation of the ethyl acetate (EtOAc) extract from a marine-derived…”
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2
New Angucycline Glycosides from a Marine-Derived Bacterium Streptomyces ardesiacus
Published in International journal of molecular sciences (09-11-2022)“…Chemical investigation of the ethyl acetate extract from the culture broth of the marine-derived actinobacterium 156VN-095 led to the isolation of three…”
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3
Rifamycin-Related Polyketides from a Marine-Derived Bacterium Salinispora arenicola and Their Cytotoxic Activity
Published in Marine drugs (15-09-2023)“…Eight rifamycin-related polyketides were isolated from the culture broth of a marine-derived bacterium Salinispora arenicola, including five known (2–5 and 8)…”
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4
Targeted Induction of Endogenous VDUP1 by Small Activating RNA Inhibits the Growth of Lung Cancer Cells
Published in International journal of molecular sciences (13-07-2022)“…Recent studies have reported that small double-strand RNAs (dsRNAs) can activate endogenous genes via an RNA-based promoter targeting mechanism termed RNA…”
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5
Sesquiterpenes from Streptomyces qinglanensis and Their Cytotoxic Activity
Published in Marine drugs (16-06-2023)“…Nine sesquiterpenes, including eight pentalenenes ( - ) and one bolinane derivative ( ), were isolated from the culture broth of a marine-derived…”
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6
Inhibition of Skin Inflammation by Scytonemin, an Ultraviolet Sunscreen Pigment
Published in Marine drugs (04-06-2020)“…Scytonemin is a yellow-green ultraviolet sunscreen pigment present in different genera of aquatic and terrestrial blue-green algae, including marine…”
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Design, synthesis, and evaluation of novel (E)‐N'‐(3‐allyl‐2‐hydroxy)benzylidene‐2‐(4‐oxoquinazolin‐3(4H)‐yl)acetohydrazides as antitumor agents
Published in Archiv der Pharmazie (Weinheim) (01-01-2022)“…In our continuing search for novel small‐molecule anticancer agents, we designed and synthesized a series of novel…”
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8
Antibacterial and Cytotoxic Phenolic Polyketides from Two Marine-Derived Fungal Strains of Aspergillus unguis
Published in Pharmaceuticals (Basel, Switzerland) (06-01-2022)“…A chemical investigation on the EtOAc extracts from two marine-derived fungal strains of resulted in the isolation of three previously undescribed phenolic…”
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9
Protection against Lipopolysaccharide-Induced Endotoxemia by Terrein Is Mediated by Blocking Interleukin-1β and Interleukin-6 Production
Published in Pharmaceuticals (Basel, Switzerland) (01-11-2022)“…Terrein is a fungal metabolite and has been known to exert anti-melanogenesis, anti-cancer, and anti-bacterial activities. However, its role in endotoxemia has…”
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10
Anti-Inflammatory and Anti-Urolithiasis Effects of Polyphenolic Compounds from Quercus gilva Blume
Published in Molecules (Basel, Switzerland) (05-07-2017)“…Bume (QGB, family Fagaceae) is a tall evergreen oak species tree that grows in warm temperate regions in Korea, Japan, China and Taiwan. plants have long been…”
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11
Antioxidative and anti-inflammatory effects of phenolic compounds from the roots of Ulmus macrocarpa
Published in Archives of pharmacal research (01-09-2011)“…The roots of Ulmus macrocarpa Hance (Ulmaceae) have been used as an oriental traditional medicine for the treatment of inflammation, ulcers, cancers, and…”
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12
Novel 4‑Oxoquinazoline-Based N‑Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation
Published in ACS omega (23-02-2021)“…Two series of novel 4-oxoquinazoline-based N-hydroxypropenamides (9a–m and 10a–m) were designed, synthesized, and evaluated for their inhibitory and…”
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13
The Anti-oxidative and Anti-inflammatory Effects of Caffeoyl Derivatives from the Roots of Aconitum koreanum R. RAYMOND
Published in Biological & pharmaceutical bulletin (01-12-2009)“…Activity guided fractionation of Aconitum koreanum root extract (RAK), a traditional medicine in Korea, afforded four caffeoyl derivatives, caffeic acid (1),…”
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14
Aspersterols A–D, Ergostane-Type Sterols with an Unusual Unsaturated Side Chain from the Deep-Sea-Derived Fungus Aspergillus unguis
Published in Journal of natural products (Washington, D.C.) (23-09-2022)“…Four previously undescribed ergostane-type sterols, aspersterols A–D (1–4), were isolated from a deep-sea-derived fungus, Aspergillus unguis IV17-109. The…”
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15
Three New Stereoisomers of Condensed Tannins from the Roots of Rosa multiflora
Published in Chemical & Pharmaceutical Bulletin (01-09-2010)“…Three new stereoisomers of condensed tannins (1—3), and four known phenolic compounds (4—7) were isolated from the 80% acetone extract of the roots of Rosa…”
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Triterpenoids and a sterol from the stem-bark of Styrax japonica and their protein tyrosine phosphatase 1B inhibitory activities
Published in Phytotherapy research (01-10-2008)“…Five pentacyclic triterpenoids (1-5) and a sterol (6) were isolated from the stem-bark of Styrax japonica. The six compounds, 1-6, were determined to be…”
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17
Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents
Published in Bioorganic & medicinal chemistry letters (15-11-2020)“…[Display omitted] •Three novel series of indirubin-based hydroxamic acids were synthesized.•All three series exhibited potent HDAC inhibition.•All three series…”
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18
Exploration of certain 1,3-oxazole- and 1,3-thiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents
Published in Bioorganic chemistry (01-08-2020)“…Three series of hydroxamic acids (5a-g, 6a-g, 8a-c) exhibited good cytotoxicity against three human cancer cell lines with IC50 values in low micromolar range,…”
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The antioxidant and anti-inflammatory effects of phenolic compounds isolated from the root of Rhodiola sachalinensis A. BOR
Published in Molecules (Basel, Switzerland) (27-09-2012)“…Isolation of compounds from the root of Rhodiola sachalinensis (RRS) yielded tyrosol (1), salidroside (2), multiflorin B (3),…”
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Novel (E)‐3‐(3‐Oxo‐4‐substituted‐3,4‐dihydro‐2H‐benzo[b][1,4]oxazin‐6‐yl)‐N‐hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis and Bioevaluation
Published in Chemistry & biodiversity (01-05-2023)“…Herein, we report the design, synthesis and evaluation of novel (E)‐3‐(3‐oxo‐4‐substituted‐3,4‐dihydro‐2H‐benzo[b][1,4]oxazin‐6‐yl)‐N‐hydroxypropenamides (4…”
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