Search Results - "Hedrick, Shannon E."
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The human intermediate prolactin receptor is a mammary proto-oncogene
Published in NPJ breast cancer (26-03-2021)“…The hormone prolactin (PRL) and its receptor (hPRLr) are significantly involved in breast cancer pathogenesis. The intermediate hPRLr (hPRLrI) is an…”
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Cyclophilin A Function in Mammary Epithelium Impacts Jak2/Stat5 Signaling, Morphogenesis, Differentiation, and Tumorigenesis in the Mammary Gland
Published in Cancer research (Chicago, Ill.) (15-07-2018)“…The prolyl isomerase cyclophilin A (CypA) regulates the Jak2/Stat5 pathway, which is necessary for mammary differentiation and the pathogenesis of breast…”
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Abstract P4-08-02: The human intermediate prolactin receptor is a breast cancer oncogene
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…Abstract Epidemiological, cellular, and genetic analyses indicate the hormone prolactin (PRL) and its cognate receptor in humans (hPRLr) are significantly…”
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Abstract 4508: Cyclophilin A as a molecular switch regulating PRLr-Jak2 complex-mediated signaling, mammary tumorigenesis, and metastasis
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Prolactin (PRL) and its receptor (PRLr) have been implicated in the development and progression of human breast cancer. PRL activates its receptor and…”
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