Search Results - "Hedlund, E"
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1
Altered perivascular fibroblast activity precedes ALS disease onset
Published in Nature medicine (01-04-2021)“…Apart from well-defined factors in neuronal cells 1 , only a few reports consider that the variability of sporadic amyotrophic lateral sclerosis (ALS)…”
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2
Motor neurons with differential vulnerability to degeneration show distinct protein signatures in health and ALS
Published in Neuroscience (16-04-2015)“…Highlights • The motor protein dynein is down-regulated in resistant and vulnerable motor neurons (MNs) in ALS. • The high level of Gabra1 in oculomotor MNs in…”
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3
Synaptotagmin 13 is neuroprotective across motor neuron diseases
Published in Acta neuropathologica (01-05-2020)“…In amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), spinal and lower brainstem motor neurons degenerate, but some motor neuron subtypes…”
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4
Neuronal cell replacement in Parkinson’s disease
Published in Journal of internal medicine (01-10-2009)“… Transplantation of foetal dopamine neurons into the striatum of Parkinson’s disease patients can provide restoration of the dopamine system and alleviate…”
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Journal Article Conference Proceeding -
5
Month of birth and the risk of developing type 1 diabetes among children in the Swedish national Better Diabetes Diagnosis Study
Published in Acta Paediatrica (01-12-2022)“…Aim Previous studies have reported an association between month of birth and incidence of type 1 diabetes. Using population‐based data, including almost all…”
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6
Antiangiogenic agents significantly improve survival in tumor-bearing mice by increasing tolerance to chemotherapy-induced toxicity
Published in Proceedings of the National Academy of Sciences - PNAS (08-03-2011)“…Chemotherapy-induced broad toxicities are the leading cause of the drug-induced mortality in cancer patients. Antiangiogenic drugs (ADs) in combination with…”
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7
Genetic selection of sox1GFP‐expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation
Published in Journal of neurochemistry (01-06-2006)“…Because of their ability to proliferate and to differentiate into diverse cell types, embryonic stem (ES) cells are a potential source of cells for…”
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8
PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells
Published in Nature medicine (01-01-2012)“…The cytokine PDGF has multiple effects on the vasculature and influences tumor growth and progression. Yuan Xue et al . uncover a new role for PDGF as a…”
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9
Soy isoflavonoid equol modulates the growth of benign and malignant prostatic epithelial cells in vitro
Published in The Prostate (01-01-2003)“…BACKGROUND The dietary consumption of high levels of soy has been linked to reduced risks for prostate cancer (PC) in Asians and vegetarians. In vitro studies…”
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10
Sizable variations in circulatory disease mortality by region and country of birth in six European countries
Published in European journal of public health (01-08-2013)“…Circulatory disease mortality inequalities by country of birth (COB) have been demonstrated for some EU countries but pan-European analyses are lacking. We…”
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11
Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis
Published in The Journal of clinical investigation (01-10-2007)“…Tumors produce multiple growth factors, but little is known about the interplay between various angiogenic factors in promoting tumor angiogenesis, growth, and…”
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Journal Article -
12
R Regulation of tumor angiogenesis and metastasis by FGF and PDGF signaling pathways
Published in Journal of molecular medicine (Berlin, Germany) (01-07-2008)“…In a fast-growing malignant tissue, tumor blood vessels are exposed to multiple growth factors and cytokines. Although the role of individual factors and their…”
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Journal Article -
13
Long-term dietary habits affect soy isoflavone metabolism and accumulation in prostatic fluid in caucasian men
Published in The Journal of nutrition (01-06-2005)“…The soy isoflavones daidzein and genistein are believed to reduce prostate cancer risk in soy consumers. However, daidzein can be metabolized by the intestinal…”
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14
The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons
Published in Molecular and cellular neuroscience (01-02-2005)“…The A9 dopaminergic (DA) neuronal group projecting to the dorsal striatum is the most vulnerable in Parkinson's disease (PD). We genetically engineered mouse…”
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15
Selective international migration by social position, health behaviour and personality
Published in European journal of public health (01-04-2008)“…Background: Immigrants is an important minority in many countries, but little is known how they are self-selected. We analysed differences in psycho-social and…”
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16
Quasi-static and dynamic electromechanical response of piezoelectric multilayer cantilever beams
Published in Sensors and actuators. A. Physical. (01-02-2010)“…Piezoelectric multilayer cantilever beams were considered with the aim to establish a simple but general theoretical model, fabricate such beams by a procedure…”
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17
Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro
Published in The Prostate (01-04-2006)“…BACKGROUND The differential intestinal metabolism of the soy isoflavones is likely to influence the ability of soy to prevent prostate cancer. While daidzein,…”
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Journal Article -
18
Vitamin D, liver-related biomarkers, and distribution of fat and lean mass in young patients with Fontan circulation
Published in Cardiology in the young (01-06-2022)“…Young patients with Fontan circulation may have low serum 25-hydroxyvitamin D levels, an affected liver, and unhealthy body compositions. This study aimed to…”
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19
Sickle hemoglobin oxygen affinity‐shifting strategies have unequal cerebrovascular risks
Published in American journal of hematology (01-03-2018)Get full text
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20
Mouse corneal lymphangiogenesis model
Published in Nature protocols (01-06-2011)“…This protocol describes a powerful in vivo method to quantitatively study the formation of new lymphatic vessels in the avascular cornea without interference…”
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