Search Results - "Hedgpeth, Joe"
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Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection
Published in Journal of molecular and cellular cardiology (01-10-2014)“…Abstract Activation of RhoA, a low molecular-weight G-protein, plays an important role in protecting the heart against ischemic stress. Studies using…”
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2
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell
Published in Proceedings of the National Academy of Sciences - PNAS (02-11-2010)“…The conversion of mature somatic cells into pluripotent stem cells, both by nuclear transfer and transduction with specific “reprogramming” genes, represents a…”
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3
Analysis of protein kinase C theta inhibitors for the control of HIV-1 replication in human CD4+ T cells reveals an effect on retrotranscription in addition to viral transcription
Published in Biochemical pharmacology (15-04-2015)“…PKCθ inhibitors CGX1079 and CGX0471 interfere with HIV-1 replication at viral transcription, through the inhibition of NF-κB, NFAT and AP-1 activation, and at…”
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4
3'-minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures
Published in Nucleic acids research (15-01-2000)“…DNA probes with conjugated minor groove binder (MGB) groups form extremely stable duplexes with single-stranded DNA targets, allowing shorter probes to be used…”
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5
Critical Role of the Small GTPase RhoA in the Development of Pulmonary Edema Induced by Pseudomonas aeruginosa in Mice
Published in Anesthesiology (Philadelphia) (01-11-2010)“…Pseudomonas aeruginosa is an opportunistic pathogen that can cause severe pneumonia in critically ill patients. We have reported previously that P. aeruginosa…”
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6
3'-Minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures
Published in Nucleic acids research (15-01-2000)Get full text
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7
DNA Nucleotide Sequence Restricted by the RI Endonuclease
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1972)“…The sequence of DNA base pairs adjacent to the phosphodiester bonds cleaved by the RI restriction endonuclease in unmodified DNA from coliphage λ has been…”
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8
Prevention of Autoimmune Demyelination in Non-Human Primates by a cAMP- Specific Phosphodiesterase Inhibitor
Published in Proceedings of the National Academy of Sciences - PNAS (11-04-1995)“…Experimental allergic encephalomyelitis (EAE) is an autoimmune disease of the central nervous system that serves as a model for the human disease multiple…”
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The effects of recombinant human thrombomodulin on endotoxin-induced multiple-system organ failure in rats
Published in American journal of respiratory and critical care medicine (01-06-1996)“…Activation of the coagulation system is postulated to play an important role in the pathogenesis of endotoxin-induced tissue injury. Thrombomodulin (TM) is an…”
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10
A stop transfer sequence confers predictable transmembrane orientation to a previously secreted protein in cell-free systems
Published in Cell (01-10-1983)“…We have combined molecular genetic and cell-free reconstitution approaches to study the mechanism of membrane assembly. The coding region for the…”
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11
Reiterative copying by E.coli RNA polymerase during transcription initiation of mutant pBR322 tet promoters
Published in Nucleic acids research (11-02-1990)“…The major in vitro transcripts from the tet promoter of pBR322 derivatives pTA22 and pTA33 have heterogeneous 5' ends consisting of variable lengths of…”
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12
Determinants for Protein Localization: β -Lactamase Signal Sequence Directs Globin across Microsomal Membranes
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1984)“…A hybrid gene containing 182 codons of Escherichia coli β -lactamase at the amino terminus of the corresponding protein and 141 codons of α -globin at the…”
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13
Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein
Published in Nature (London) (08-05-1980)“…The amino-terminal signal sequence is required for initiation of transmembrane protein transfer of the Escherichia coli lambda receptor protein. Mutations…”
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14
DNA Sequence Encoding the NH2-terminal Peptide Involved in Transport of λ Receptor, an Escherichia coli Secretory Protein
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1980)“…lamB encodes the λ receptor of Escherichia coli, an outer membrane protein. We have identified the beginning of the lamB gene by correlation DNA nucleotide…”
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15
Transcription initiation at the tet promoter and effect of mutations
Published in Nucleic acids research (11-08-1988)“…We have identified the startpoint for transcription in vitro of the tetracycline resistance gene (tet) of pBR322 and several deletion and insertion mutations…”
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16
Physical identity of the SV40 deoxyribonucleic acid sequence recognized by the Eco RI restriction endonuclease and modification methylase
Published in Biochemistry (Easton) (01-01-1974)Get full text
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17
Synthesis and Maturation of λ Receptor in Escherichia coli K-12: In vivo and in vitro Expression of Gene lamB under lac Promoter Control
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1980)“…The λ receptor is an outer membrane protein from Escherichia coli K-12. lamB, its structural gene, is part of the maltose regulon. We have cloned this gene in…”
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18
Analysis of lambda receptor and beta-lactamase synthesis and export using cloned genes in a minicell system
Published in Molecular & general genetics (01-04-1982)“…We have cloned lamB, the gene for lambda receptor (an outer membrane protein), on a small plasmid which also carries the gene for beta-lactamase (a periplasmic…”
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19
Lambda phage promoter used to enhance expression of a plasmid-cloned gene
Published in Molecular & general genetics (01-01-1978)“…A 50-fold (or greater) increase in the production of phage 21 repressor was obtained by construction of a plasmid in which the 21cI (repressor) gene could be…”
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20
Deletions of Lambda Phage Locating a prm Mutation within the Rightward Operator
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1976)“…Two deletion-substitution mutations of phage λ , spi-113 and spi-274, are shown to remove about half of the rightward operator OR. Physiological studies show…”
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