Search Results - "Hederer, Bettina"
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Effect of once-daily indacaterol maleate/mometasone furoate on exacerbation risk in adolescent and adult asthma: a double-blind randomised controlled trial
Published in BMJ open (03-02-2015)“…Objective To investigate the safety and efficacy of QMF149, a once-daily, fixed-dose combination of the long-acting β2-agonist (LABA) indacaterol maleate and…”
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Study design considerations in a large COPD trial comparing effects of tiotropium with salmeterol on exacerbations
Published in International journal of chronic obstructive pulmonary disease (2009)“…Currently available long-acting inhaled bronchodilators (tiotropium, salmeterol, formoterol) have demonstrated beneficial effects on exacerbations in…”
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Tiotropium versus Salmeterol for the Prevention of Exacerbations of COPD
Published in The New England journal of medicine (24-03-2011)“…An important goal in the treatment of COPD is the prevention of exacerbations. In this trial, the investigators found that treatment with tiotropium, as…”
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Pharmacokinetics of mometasone furoate delivered via two dry powder inhalers
Published in Pulmonary pharmacology & therapeutics (01-10-2021)“…QMF149 is an inhaled fixed-dose combination of indacaterol acetate and mometasone furoate (MF) delivered via Breezhaler®, under development for once-daily…”
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Potential systemic effects of acquired CFTR dysfunction in COPD
Published in Respiratory medicine (01-01-2024)“…Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation, respiratory symptoms, inflammation of the airways, and systemic…”
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A randomized, double-blind study to compare the efficacy and safety of two doses of mometasone furoate delivered via Breezhaler® or Twisthaler® in patients with asthma
Published in Pulmonary pharmacology & therapeutics (01-06-2020)“…Mometasone furoate (MF) is the inhaled corticosteroid (ICS) component in the long-acting β2-agonist (LABA)/ICS fixed-dose combination of indacaterol/MF,…”
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Higher lung deposition with Respimat Soft Mist inhaler than HFA-MDI in COPD patients with poor technique
Published in International journal of chronic obstructive pulmonary disease (2008)“…Aerosols delivered by Respimat Soft Mist Inhaler (SMI) are slower-moving and longer-lasting than those from pressurized metered-dose inhalers (pMDIs),…”
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Indacaterol acetate/mometasone furoate provides sustained improvements in lung function compared with salmeterol xinafoate/fluticasone propionate in patients with moderate-to-very-severe COPD: results from a Phase II randomized, double-blind 12-week study
Published in International journal of chronic obstructive pulmonary disease (01-01-2018)“…Fixed-dose combinations of a long-acting beta agonist and an inhaled corticosteroid are more effective than the individual components in COPD. The primary…”
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Higher lung deposition with Respimat super(ARG) Soft Mist super(ac) Inhaler than HFA-MDI in COPD patients with poor technique
Published in International journal of chronic obstructive pulmonary disease (01-12-2008)“…Aerosols delivered by Respimat super(ARG) Soft Mist super(ac) Inhaler (SMI) are slower-moving and longer-lasting than those from pressurized metered-dose…”
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Higher lung deposition with Respimat reg; Soft Mist trade; Inhaler than HFA-MDI in COPD patients with poor technique
Published in International journal of chronic obstructive pulmonary disease (01-08-2008)“…Peter Brand1, Bettina Hederer2, George Austen3, Helen Dewberry3, Thomas Meyer41RWTH, Aachen, Germany; 2Boehringer Ingelheim, Ingelheim, Germany; 3Boehringer…”
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