Search Results - "Hector Iglesias"
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1
Homeostatic alterations related to total antioxidant capacity, elemental concentrations and isotopic compositions in aqueous humor of glaucoma patients
Published in Analytical and bioanalytical chemistry (01-01-2022)“…Glaucoma is a multifactorial eye disease, characterized by progressive optic neurodegeneration. Elevation of the intraocular pressure is the main risk factor…”
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2
Genetic and immune landscape evolution in MMR-deficient colorectal cancer
Published in The Journal of pathology (01-02-2024)“…Mismatch repair-deficient (MMRd) colorectal cancers (CRCs) have high mutation burdens, which make these tumours immunogenic and many respond to immune…”
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3
Antioxidant Defenses in the Human Eye: A Focus on Metallothioneins
Published in Antioxidants (11-01-2021)“…The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of endogenous and exogenous origin. Oxidative stress affects all…”
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4
Clinical significance of baseline Pan-Immune-Inflammation Value and its dynamics in metastatic colorectal cancer patients under first-line chemotherapy
Published in Scientific reports (27-04-2022)“…Pan-Immune-Inflammation Value (PIV) has been recently proposed as a new blood-based prognostic biomarker in metastatic colorectal cancer (mCRC). Herein we…”
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5
Nasal exudate for diagnosis of stroke: fundamental studies through iron fractionation, total iron, and targeted protein determinations
Published in Analytical and bioanalytical chemistry (01-10-2024)“…During the last years, there has been an increasing research interest in the analysis of biological fluids requiring non-invasive sampling for biomedical and…”
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6
Multiple heart-cutting two dimensional liquid chromatography and isotope dilution tandem mass spectrometry for the absolute quantification of proteins in human serum
Published in Analytica chimica acta (01-11-2021)“…We evaluate here the combination of two-dimensional liquid chromatography (2D-LC) in the multiple heart cutting mode and isotope dilution tandem mass…”
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7
The Zinc-Metallothionein Redox System Reduces Oxidative Stress in Retinal Pigment Epithelial Cells
Published in Nutrients (02-12-2018)“…Oxidative stress affects all the structures of the human eye, particularly the retina and its retinal pigment epithelium (RPE). The RPE limits oxidative damage…”
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8
Bimodal determination of immunoglobulin E by fluorometry and ICP-MS by using platinum nanoclusters as a label in an immunoassay
Published in Mikrochimica acta (1966) (01-11-2019)“…The authors describe the use of platinum nanoclusters (PtNCs) as bimodal labels in a competitive immunoassay for immunoglobulin E (IgE). Both fluorometry and…”
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9
Determination and localization of specific proteins in individual ARPE-19 cells by single cell and laser ablation ICP-MS using iridium nanoclusters as label
Published in Talanta (Oxford) (01-02-2023)“…Single cell-inductively coupled plasma-mass spectrometry (sc-ICP-MS) and laser ablation (LA)-ICP-MS have been complementary employed to develop a comprehensive…”
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10
The association study of lipid metabolism gene polymorphisms with AMD identifies a protective role for APOE‐E2 allele in the wet form in a Northern Spanish population
Published in Acta ophthalmologica (Oxford, England) (01-05-2020)“…Purpose To elucidate the potential role of eleven single nucleotide polymorphisms (SNPs) in the most relevant lipid metabolism genes in Northern Spanish…”
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11
Real-time personal protective equipment monitoring system
Published in Computer communications (01-12-2012)“…The use of personal protective equipment (PPEs) in the construction industry is necessary to guarantee the safety of the workers. However, this equipment is…”
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12
Identification and characterization of a new pathologic mutation in a large Leber hereditary optic neuropathy pedigree
Published in Orphanet journal of rare diseases (06-04-2024)“…Most patients suffering from Leber hereditary optic neuropathy carry one of the three classic pathologic mutations, but not all individuals with these genetic…”
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13
Longitudinal PET/CT evaluation of TNBS-induced inflammatory bowel disease rat model
Published in International journal of pharmaceutics (05-10-2018)“…[Display omitted] Inflammatory bowel disease (IBD) is a group of chronic disorders of the gastrointestinal tract, which two main types are Crohn’s disease and…”
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14
Evaluation of the therapeutic activity of melatonin and resveratrol in Inflammatory Bowel Disease: A longitudinal PET/CT study in an animal model
Published in International journal of pharmaceutics (15-12-2019)“…[Display omitted] Inflammatory Bowel Disease (IBD) is a group of chronic disorders of the gastrointestinal tract, which two main types are Crohn’s disease and…”
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15
The Use of Vitamins and Coenzyme Q10 for the Treatment of Vascular Occlusion Diseases Affecting the Retina
Published in Nutrients (09-03-2020)“…Nutritional supplementation with antioxidants and vitamins is widely recommended in the treatment of vascular disorders affecting the retina, although there is…”
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16
3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease
Published in Biomedicines (02-12-2020)“…The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using semisolid extrusion 3-dimensional printing (3DP) and to investigate…”
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17
Quantitative study of zinc and metallothioneins in the human retina and RPE cells by mass spectrometry-based methodologies
Published in Talanta (Oxford) (01-02-2018)“…The retina contains the highest concentration of zinc in the human eye and it is primarily associated with the retinal pigment epithelium (RPE)…”
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18
Candidate Glaucoma Biomarkers: From Proteins to Metabolites, and the Pitfalls to Clinical Applications
Published in Biology (Basel, Switzerland) (10-08-2021)“…Glaucoma is an insidious group of eye diseases causing degeneration of the optic nerve, progressive loss of vision, and irreversible blindness. The number of…”
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19
CFH polymorphisms in a Northern Spanish population with neovascular and dry forms of age‐related macular degeneration
Published in Acta ophthalmologica (Oxford, England) (01-12-2015)“…Purpose To elucidate the potential role of single‐nucleotide polymorphisms (SNPs) in complement factor H (CFH) gene in Northern Spanish patients with…”
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20
Quantitative bioimaging of trace elements in the human lens by LA-ICP-MS
Published in Analytical and bioanalytical chemistry (01-04-2014)“…Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was used for the quantitative imaging of Fe, Cu and Zn in cryostat sections of human…”
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