Search Results - "Hebbar, Shilpa"
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Functional identification of microRNA-centered complexes in C. elegans
Published in Scientific reports (03-05-2022)“…microRNAs (miRNAs) are crucial for normal development and physiology. To identify factors that might coordinate with miRNAs to regulate gene expression, we…”
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Journal Article -
2
Global profiling and annotation of templated isomiRs dynamics across Caenorhabditis elegans development
Published in RNA biology (31-12-2022)“…microRNAs (miRNAs) are small non-coding RNAs that regulate gene expression through translational repression and mRNA destabilization. During canonical miRNA…”
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Journal Article -
3
Uncovering miRNA Regulatory Mechanisms Through Functional Assessment of miRNA Centered Complexes During C. Elegans Development
Published 01-01-2022“…Normal developmental and physiological processes depend on precise regulation of gene expression. miRNAs are a class of small non-coding RNAs that…”
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Dissertation -
4
Single nucleotide substitutions effectively block Cas9 and allow for scarless genome editing in Caenorhabditis elegans
Published in Genetics (Austin) (04-01-2022)“…Abstract In Caenorhabditis elegans, germline injection of Cas9 complexes is reliably used to achieve genome editing through homology-directed repair of…”
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Journal Article -
5
An engineered, orthogonal auxin analog/ At TIR1(F79G) pairing improves both specificity and efficacy of the auxin degradation system in Caenorhabditis elegans
Published in Genetics (Austin) (04-02-2022)“…Abstract The auxin-inducible degradation system in C. elegans allows for spatial and temporal control of protein degradation via heterologous expression of a…”
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Journal Article -
6
An engineered, orthogonal auxin analog/AtTIR1(F79G) pairing improves both specificity and efficacy of the auxin degradation system in Caenorhabditis elegans
Published in Genetics (Austin) (04-02-2022)“…Abstract The auxin-inducible degradation system in C. elegans allows for spatial and temporal control of protein degradation via heterologous expression of a…”
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Journal Article -
7
Two new CRISPR-generated alleles in the C. elegans mir-1022 gene
Published in microPublication biology (01-04-2020)Get full text
Journal Article -
8
Two novel alleles in C. elegans mir-1822 gene
Published in microPublication biology (16-01-2020)Get full text
Journal Article -
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Two Deletion Alleles in the C. elegans mir-49 gene
Published in microPublication biology (01-04-2020)Get full text
Journal Article