Search Results - "Heather, Davies"
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1
Elastohydrodynamic Lift at a Soft Wall
Published in Physical review letters (11-05-2018)“…We study experimentally the motion of nondeformable microbeads in a linear shear flow close to a wall bearing a thin and soft polymer layer. Combining…”
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2
Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro
Published in PloS one (05-12-2013)“…The blood-brain barrier prevents the entry of many therapeutic agents into the brain. Various nanocarriers have been developed to help agents to cross this…”
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3
Natalizumab treatment satisfaction in the TONiC-MS study: latest results
Published in Journal of neurology, neurosurgery and psychiatry (28-11-2023)“…BackgroundMS patients’ perceptions and treatment satisfaction with natalizumab-i.v., plus experiences if they switch from natalizumab-i.v. to natalizumab-s.c.,…”
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4
Diroximel fumarate pregnancy outcomes in EVOLVE-MS-1 and prospective MS pregnancy exposure registry study design
Published in Journal of neurology, neurosurgery and psychiatry (28-11-2023)“…ObjectiveReport pregnancy outcomes from diroximel fumarate (DRF)-exposed women with multiple sclerosis (MS) in EVOLVE-MS-1, and describe a prospective,…”
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5
Results from a Phase 1/2 trial of BB2603, a terbinafine‐based topical nano‐formulation, in onychomycosis and tinea pedis
Published in Mycoses (01-06-2022)“…BB2603 is a nano‐formulation of the antifungal drug terbinafine with the polymer polyhexamethylene biguanide (PHMB) as an excipient to enhance solubility and…”
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6
Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells
Published in The Journal of immunology (1950) (15-09-2012)“…During neuroinflammation, cytokines such as TNF-α and IFN-γ secreted by activated leukocytes and/or CNS resident cells have been shown to alter the phenotype…”
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7
Secondary Structure and Glycosylation of Mucus Glycoproteins by Raman Spectroscopies
Published in Analytical chemistry (Washington) (06-12-2016)“…The major structural components of protective mucus hydrogels on mucosal surfaces are the secreted polymeric gel-forming mucins. The very high molecular weight…”
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Genomic Surveillance of a Globally Circulating Distinct Group W Clonal Complex 11 Meningococcal Variant, New Zealand, 2013-2018
Published in Emerging infectious diseases (01-04-2021)“…Genomic surveillance is an essential part of effective disease control, enabling identification of emerging and expanding strains and monitoring of subsequent…”
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9
An integrated assay to probe endothelial glycocalyx-blood cell interactions under flow in mechanically and biochemically well-defined environments
Published in Matrix biology (01-05-2019)“…Cell-cell and cell-glycocalyx interactions under flow are important for the behaviour of circulating cells in blood and lymphatic vessels. However, such…”
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10
Quantified moorland vegetation and assessment of the role of burning over the past five millennia
Published in Journal of vegetation science (01-05-2018)“…Aims: To apply the Landscape Reconstruction Algorithm (LRA) to pollen count data from multiple sites to estimate local vegetation abundance and compare with…”
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11
Reorganisation of the salivary mucin network by dietary components: insights from green tea polyphenols
Published in PloS one (29-09-2014)“…The salivary mucins that include MUC5B (gel-forming) and MUC7 (non-gel-forming) are major contributors to the protective mucus barrier in the oral cavity, and…”
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12
Engineered neural tissue for peripheral nerve repair
Published in Biomaterials (01-10-2013)“…Abstract A new combination of tissue engineering techniques provides a simple and effective method for building aligned cellular biomaterials. Self-alignment…”
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13
Expression of Chemokines and Their Receptors by Human Brain Endothelium: Implications for Multiple Sclerosis
Published in Journal of neuropathology and experimental neurology (01-03-2009)“…Leukocyte migration into the central nervous system (CNS) is mediated by chemokines expressed on CNS endothelial cell surfaces. This study investigated the…”
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14
Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition
Published in Proceedings of the National Academy of Sciences - PNAS (11-10-2011)“…Stress has been identified as a major causal factor for many mental disorders. However, our knowledge about the chain of molecular and cellular events…”
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15
Text mining for disease surveillance in veterinary clinical data: part two, training computers to identify features in clinical text
Published in Frontiers in veterinary science (22-08-2024)“…In part two of this mini-series, we evaluate the range of machine-learning tools now available for application to veterinary clinical text-mining. These tools…”
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16
Mitochondria form a filamentous reticular network in hippocampal dendrites but are present as discrete bodies in axons: A three-dimensional ultrastructural study
Published in Journal of comparative neurology (1911) (07-11-2005)“…The fine structure of mitochondria and smooth endoplasmic reticulum (SER) was studied via electron microscopy in dendritic and axonal neuronal segments of…”
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17
Amyloid-beta induced CA1 pyramidal cell loss in young adult rats is alleviated by systemic treatment with FGL, a neural cell adhesion molecule-derived mimetic peptide
Published in PloS one (09-08-2013)“…Increased levels of neurotoxic amyloid-beta in the brain are a prominent feature of Alzheimer's disease. FG-Loop (FGL), a neural cell adhesion molecule-derived…”
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Text mining for disease surveillance in veterinary clinical data: part one, the language of veterinary clinical records and searching for words
Published in Frontiers in veterinary science (2024)“…The development of natural language processing techniques for deriving useful information from unstructured clinical narratives is a fast-paced and rapidly…”
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19
Assessment of the nail penetration of antifungal agents, with different physico-chemical properties
Published in PloS one (27-02-2020)“…Onychomycosis, or fungal nail infection, is a common fungal infection largely caused by dermatophyte fungi, such as Trichophyton rubrum or Trichophyton…”
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Early structural and functional defects in synapses and myelinated axons in stratum lacunosum moleculare in two preclinical models for tauopathy
Published in PloS one (03-02-2014)“…The stratum lacunosum moleculare (SLM) is the connection hub between entorhinal cortex and hippocampus, two brain regions that are most vulnerable in…”
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