Search Results - "Heather, Alison"

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  1. 1

    Myths and Methodologies: Reducing scientific design ambiguity in studies comparing sexes and/or menstrual cycle phases by Sims, Stacy T., Heather, Alison K.

    Published in Experimental physiology (01-10-2018)
    “…New Findings What is the topic of this review? We review methodological considerations for the inclusion of women in sex and menstrual cycle phase comparison…”
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    Journal Article
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    Transwoman Elite Athletes: Their Extra Percentage Relative to Female Physiology by Heather, Alison K.

    “…There is increasing debate as to whether transwoman athletes should be included in the elite female competition. Most elite sports are divided into male and…”
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    Journal Article
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    Apolipoprotein-AI mimetic peptides D-4F and L-5F decrease hepatic inflammation and increase insulin sensitivity in C57BL/6 mice by McGrath, Kristine C, Li, Xiaohong, Twigg, Stephen M, Heather, Alison K

    Published in PloS one (08-01-2020)
    “…Apolipoprotein-AI (apo-AI) is the major apolipoprotein found in high density lipoprotein particles (HDLs). We previously demonstrated that apo-AI injected…”
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    Journal Article
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    Definition of the estrogen negative feedback pathway controlling the GnRH pulse generator in female mice by McQuillan, H. James, Clarkson, Jenny, Kauff, Alexia, Han, Su Young, Yip, Siew Hoong, Cheong, Isaiah, Porteous, Robert, Heather, Alison K., Herbison, Allan E.

    Published in Nature communications (02-12-2022)
    “…The mechanisms underlying the homeostatic estrogen negative feedback pathway central to mammalian fertility have remained unresolved. Direct measurement of…”
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    Journal Article
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    Bioactivity of 11 keto and hydroxy androgens in yeast and mammalian host cells by Handelsman, David J., Cooper, Elliot R., Heather, Alison K.

    “…•11 keto or hydroxy androgens circulate at levels like testosterone in women.•Androgenic bioactivity was evaluated using in vitro yeast or mammalian host…”
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    CRISPR-Cas9 knockdown of ESR1 in preoptic GABA-kisspeptin neurons suppresses the preovulatory surge and estrous cycles in female mice by Clarkson, Jenny, Yip, Siew Hoong, Porteous, Robert, Kauff, Alexia, Heather, Alison K, Herbison, Allan E

    Published in eLife (21-12-2023)
    “…Evidence suggests that estradiol-sensing preoptic area GABA neurons are involved in the preovulatory surge mechanism necessary for ovulation. In vivo…”
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    Effects of High-Density Lipoproteins on Pancreatic β-Cell Insulin Secretion by Fryirs, Michelle A, Barter, Philip J, Appavoo, Mathiyalagan, Tuch, Bernard E, Tabet, Fatiha, Heather, Alison K, Rye, Kerry-Anne

    “…OBJECTIVE—Type 2 diabetes is characterized by impaired β-cell secretory function, insulin resistance, reduced high-density lipoprotein (HDL) levels, and…”
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  8. 8

    Are Antioxidants a Potential Therapy for FSHD? A Review of the Literature by Denny, Adam Philip, Heather, Alison K.

    Published in Oxidative medicine and cellular longevity (01-01-2017)
    “…Facioscapulohumeral muscular dystrophy (FSHD) is an inherited myopathy affecting approximately 1 in 7500 individuals worldwide. It is a progressive disease…”
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  9. 9

    Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL by Lim, Hwee Ying, Thiam, Chung Hwee, Yeo, Kim Pin, Bisoendial, Radjesh, Hii, Chung Shii, McGrath, Kristine C.Y., Tan, Kar Wai, Heather, Alison, Alexander, J. Steven Jonathan, Angeli, Veronique

    Published in Cell metabolism (07-05-2013)
    “…Removal of cholesterol from peripheral tissues to the bloodstream via reverse cholesterol transport (RCT) is a process of major biological importance. Here we…”
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    CaMKII Splice Variants in Vascular Smooth Muscle Cells: The Next Step or Redundancy? by Roberts-Craig, Finn T., Worthington, Luke P., O’Hara, Samuel P., Erickson, Jeffrey R., Heather, Alison K., Ashley, Zoe

    “…Vascular smooth muscle cells (VSMCs) help to maintain the normal physiological contractility of arterial vessels to control blood pressure; they can also…”
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  11. 11

    Estrogen Receptor Control of Atherosclerotic Calcification and Smooth Muscle Cell Osteogenic Differentiation by McRobb, Lucinda S, McGrath, Kristine C.Y, Tsatralis, Tania, Liong, Eleanore C, Tan, Joanne T.M, Hughes, Gillian, Handelsman, David J, Heather, Alison K

    “…OBJECTIVE—Vascular calcification is associated with increased risk of myocardial infarction and stroke. The objective of this work was to examine the ability…”
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  12. 12

    High-Density Lipoproteins Suppress Chemokines and Chemokine Receptors In Vitro and In Vivo by Bursill, Christina A, Castro, Maria L, Beattie, Douglas T, Nakhla, Shirley, van der Vorst, Emiel, Heather, Alison K, Barter, Philip J, Rye, Kerry-Anne

    “…OBJECTIVE—To investigate whether high-density lipoproteins (HDLs) suppress chemokine (CCL2, CCL5, and CX3CL1) and chemokine receptor (CCR2 and CX3CR1)…”
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    A Timing Effect of 17-β Estradiol on Atherosclerotic Lesion Development in Female ApoE -/- Mice by Ebenebe, Obialunanma V, Ashley, Zoe, Erickson, Jeffrey R, Heather, Alison K

    “…Differences in size or composition of existing plaques at the initiation of estrogen (E2) therapy may underpin evidence of increased risk of…”
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    A sex-specific role for androgens in angiogenesis by Sieveking, Daniel P, Lim, Patrick, Chow, Renée W Y, Dunn, Louise L, Bao, Shisan, McGrath, Kristine C Y, Heather, Alison K, Handelsman, David J, Celermajer, David S, Ng, Martin K C

    Published in The Journal of experimental medicine (15-02-2010)
    “…Mounting evidence suggests that in men, serum levels of testosterone are negatively correlated to cardiovascular and all-cause mortality. We studied the role…”
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  16. 16

    A cell‐free bioassay for the detection of androgens by Cooper, Elliot R., Hughes, Gillian, Kauff, Alexia, Sutherland, Emma, Ashley, Zoe, Heather, Alison K.

    Published in Drug testing and analysis (01-05-2021)
    “…Androgens remain abused performance‐enhancing drugs in sports. Technologies based on mass spectrometry can detect all forms of androgens but fail if the…”
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  17. 17

    The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages by Lane, Amanda E, Tan, Joanne T M, Hawkins, Clare L, Heather, Alison K, Davies, Michael J

    Published in Biochemical journal (15-08-2010)
    “…MPO (myeloperoxidase) catalyses the oxidation of chloride, bromide and thiocyanate by hydrogen peroxide to HOCl (hypochlorous acid), HOBr (hypobromous acid)…”
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    Nontargeted detection of designer androgens: Underestimated role of in vitro bioassays by Lund, Rachel A., Cooper, Elliot R., Wang, Hui, Ashley, Zoe, Cawley, Adam T., Heather, Alison K.

    Published in Drug testing and analysis (01-05-2021)
    “…Androgens, both steroidal and nonsteroidal in nature, are among the most commonly misused substances in competitive sports. Their recognized anabolic and…”
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  20. 20

    In vitro androgen bioassays as a detection method for designer androgens by Cooper, Elliot R, McGrath, Kristine C Y, Heather, Alison K

    Published in Sensors (06-02-2013)
    “…Androgens are the class of sex steroids responsible for male sexual characteristics, including increased muscle mass and decreased fat mass. Illicit use of…”
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