Search Results - "Heath, Robert J."

The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium by Huett, Alan, Heath, Robert J., Begun, Jakob, Sassi, Slim O., Baxt, Leigh A., Vyas, Jatin M., Goldberg, Marcia B., Xavier, Ramnik J.

“…Several species of pathogenic bacteria replicate within an intracellular vacuolar niche. Bacteria that escape into the cytosol are captured by the autophagic…”
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Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation by Cao, Zhifang, Conway, Kara L., Heath, Robert J., Rush, Jason S., Leshchiner, Elizaveta S., Ramirez-Ortiz, Zaida G., Nedelsky, Natalia B., Huang, Hailiang, Ng, Aylwin, Gardet, Agnès, Cheng, Shih-Chin, Shamji, Alykhan F., Rioux, John D., Wijmenga, Cisca, Netea, Mihai G., Means, Terry K., Daly, Mark J., Xavier, Ramnik J.

“…CARD9 is a central component of anti-fungal innate immune signaling via C-type lectin receptors, and several immune-related disorders are associated with CARD9…”
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Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity by Ng, Aylwin C.Y, Eisenberg, Jason M, Heath, Robert J.W, Huett, Alan, Robinson, Cory M, Nau, Gerard J, Xavier, Ramnik J

“…In innate immune sensing, the detection of pathogen-associated molecular patterns by recognition receptors typically involve leucine-rich repeats (LRRs). We…”
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RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy by Heath, Robert J., Goel, Gautam, Baxt, Leigh A., Rush, Jason S., Mohanan, Vishnu, Paulus, Geraldine L.C., Jani, Vijay, Lassen, Kara G., Xavier, Ramnik J.

“…Xenophagy is a form of selective autophagy that involves the targeting and elimination of intracellular pathogens through several recognition, recruitment, and…”
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Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy by Begun, Jakob, Lassen, Kara G., Jijon, Humberto B., Baxt, Leigh A., Goel, Gautam, Heath, Robert J., Ng, Aylwin, Tam, Jenny M., Kuo, Szu-Yu, Villablanca, Eduardo J., Fagbami, Lola, Oosting, Marije, Kumar, Vinod, Schenone, Monica, Carr, Steven A., Joosten, Leo A.B., Vyas, Jatin M., Daly, Mark J., Netea, Mihai G., Brown, Gordon D., Wijmenga, Cisca, Xavier, Ramnik J.

“…The polymorphism ATG16L1 T300A, associated with increased risk of Crohn’s disease, impairs pathogen defense mechanisms including selective autophagy, but…”
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Dictyostelium MEGAPs: F-BAR domain proteins that regulate motility and membrane tubulation in contractile vacuoles by Heath, Robert J.W, Insall, Robert H

“…PCH family proteins are fundamentally important proteins, linking membrane curvature events with cytoskeletal reorganisation. One group, the MEGAPs (also…”
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Control and manipulation of pathogens with an optical trap for live cell imaging of intercellular interactions by Tam, Jenny M, Castro, Carlos E, Heath, Robert J W, Cardenas, Michael L, Xavier, Ramnik J, Lang, Matthew J, Vyas, Jatin M

“…The application of live cell imaging allows direct visualization of the dynamic interactions between cells of the immune system. Some preliminary observations…”
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Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3 by Heath, Robert J W, Leong, John M, Visegrády, Balázs, Machesky, Laura M, Xavier, Ramnik J

“…Infection of host cells by pathogenic microbes triggers signal transduction pathways leading to a multitude of host cell responses including actin cytoskeletal…”
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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense by Lassen, Kara G., Kuballa, Petric, Conway, Kara L., Patel, Khushbu K., Becker, Christine E., Peloquin, Joanna M., Villablanca, Eduardo J., Norman, Jason M., Liu, Ta-Chiang, Heath, Robert J., Becker, Morgan L., Fagbami, Lola, Horn, Heiko, Mercer, Johnathan, Yilmaz, Omer H., Jaffe, Jacob D., Shamji, Alykhan F., Bhan, Atul K., Carr, Steven A., Daly, Mark J., Virgin, Herbert W., Schreiber, Stuart L., Stappenbeck, Thaddeus S., Xavier, Ramnik J.

“…A coding polymorphism (Thr300Ala) in the essential autophagy gene, autophagy related 16-like 1 (ATG16L1), confers increased risk for the development of Crohn…”
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F-BAR domains: multifunctional regulators of membrane curvature by Heath, Robert J.W, Insall, Robert H

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A New Multichannel, Coherent Amplitude Modulated, Time-Division Multiplexed, Software-Defined Radio Receiver Architecture, and Field-Programmable-Gate-Array Technology Implementation by Alluri, Veerendra Bhargav, Heath, J Robert, Lhamon, Michael

“…Some wireless communication systems must be able to receive and process signals from multiple source stations simultaneously. A common practice is to use…”
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Autophagy, immunity and human disease by Heath, Robert J, Xavier, Ramnik J

“…PURPOSE OF REVIEWTo give an overview of autophagy and its effects on innate and adaptive immunity and touch on some of the roles of autophagy in disease…”
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A Handheld Programmable-Logic-Device-Based Temperature and Relative-Humidity Sensor, Processor, and Display System Platform for Automation and Control of Industry Processes by Tangirala, Kalyan Phani, Heath, J Robert, Radun, Arthur, Conners, Terrance E

“…The development, testing, and validation of a small versatile battery-powered handheld programmable-logic-device (PLD)-based temperature and relative-humidity…”
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Use of an optical trap for study of host-pathogen interactions for dynamic live cell imaging by Tam, Jenny M, Castro, Carlos E, Heath, Robert J W, Mansour, Michael K, Cardenas, Michael L, Xavier, Ramnik J, Lang, Matthew J, Vyas, Jatin M

“…Dynamic live cell imaging allows direct visualization of real-time interactions between cells of the immune system(1, 2); however, the lack of spatial and…”
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Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity by Ng, Aylwin C Y, Eisenberg, Jason M, Heath, Robert J W, Huett, Alan, Robinson, Cory M, Nau, Gerard J, Xavier, Ramnik J

“…In innate immune sensing, the detection of pathogen-associated molecular patterns by recognition receptors typically involve leucine-rich repeats (LRRs). We…”
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PARALLEX: a parallel approach to switchbox routing by Tae Won Cho, Pyo, S.S., Heath, J.R.

“…A parallel algorithm, called PARALLEX, which uses a conflict resolving method, has been developed for the switchbox routing problem in a parallel processing…”
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Use of an Optical Trap for Study of Host-Pathogen Interactions for Dynamic Live Cell Imaging by Tam, Jenny M., Castro, Carlos E., Heath, Robert J. W., Mansour, Michael K., Cardenas, Michael L., Xavier, Ramnik J., Lang, Matthew J., Vyas, Jatin M.

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A Hand-Held Programmable-Logic-Device Based Temperature and Relative-Humidity Sensor, Processor and Display System Platform for Automation and Control of Industry Processes by Tangirala, P., Heath, J.R., Radun, A., Conners, T.

“…Development, testing and validation of a small battery-powered hand-held programmable-logic-device (PLD) based temperature and relative-humidity sensing,…”
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FPGA based parallel architecture implementation of Stacked Error Diffusion algorithm by Venugopal, R. K., Heath, J. R., Lau, D. L.

“…Digital halftoning is a crucial technique used in digital printers to convert a continuous-tone image into a pattern of black and white dots. Halftoning is…”
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A multi-channel coherent Amplitude Modulated Time Division Multiplexed Software Defined Radio receiver architecture for Programmable-Logic-Device technology implementation by Bhargav Alluri, V., Heath, J.R., Lhamon, M.

“…Some wireless communication systems must be able to receive and process signals from multiple source channels (stations) simultaneously. A common practice is…”
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