Search Results - "Hearn, J."

Spatio-temporal ecology of sympatric felids on Borneo. Evidence for resource partitioning? by Hearn, Andrew J, Cushman, Samuel A, Ross, Joanna, Goossens, Benoit, Hunter, Luke T B, Macdonald, David W

“…Niche differentiation, the partitioning of resources along one or more axes of a species' niche hyper-volume, is widely recognised as an important mechanism…”
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Randomized multicenter phase 2 study of pomalidomide, cyclophosphamide, and dexamethasone in relapsed refractory myeloma by Baz, Rachid C., Martin, Thomas G., Lin, Hui-Yi, Zhao, Xiuhua, Shain, Kenneth H., Cho, Hearn J., Wolf, Jeffrey L., Mahindra, Anuj, Chari, Ajai, Sullivan, Daniel M., Nardelli, Lisa A., Lau, Kenneth, Alsina, Melissa, Jagannath, Sundar

“…Pomalidomide and low-dose dexamethasone (PomDex) is standard treatment of lenalidomide refractory myeloma patients who have received >2 prior therapies. We…”
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ELF3 Controls Thermoresponsive Growth in Arabidopsis by Box, Mathew S., Huang, B. Emma, Domijan, Mirela, Jaeger, Katja E., Khattak, Asif Khan, Yoo, Seong Jeon, Sedivy, Emma L., Jones, D. Marc, Hearn, Timothy J., Webb, Alex A.R., Grant, Alastair, Locke, James C.W., Wigge, Philip A.

“…Plant development is highly responsive to ambient temperature, and this trait has been linked to the ability of plants to adapt to climate change [1]. The…”
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A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes by Kroll, François, Powell, Gareth T, Ghosh, Marcus, Gestri, Gaia, Antinucci, Paride, Hearn, Timothy J, Tunbak, Hande, Lim, Sumi, Dennis, Harvey W, Fernandez, Joseph M, Whitmore, David, Dreosti, Elena, Wilson, Stephen W, Hoffman, Ellen J, Rihel, Jason

“…Hundreds of human genes are associated with neurological diseases, but translation into tractable biological mechanisms is lagging. Larval zebrafish are an…”
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importance of correcting for sampling bias in MaxEnt species distribution models by Kramer‐Schadt, Stephanie, Niedballa, Jürgen, Pilgrim, John D, Schröder, Boris, Lindenborn, Jana, Reinfelder, Vanessa, Stillfried, Milena, Heckmann, Ilja, Scharf, Anne K, Augeri, Dave M, Cheyne, Susan M, Hearn, Andrew J, Ross, Joanna, Macdonald, David W, Mathai, John, Eaton, James, Marshall, Andrew J, Semiadi, Gono, Rustam, Rustam, Bernard, Henry, Alfred, Raymond, Samejima, Hiromitsu, Duckworth, J. W, Breitenmoser‐Wuersten, Christine, Belant, Jerrold L, Hofer, Heribert, Wilting, Andreas, Robertson, Mark

“…AIM: Advancement in ecological methods predicting species distributions is a crucial precondition for deriving sound management actions. Maximum entropy…”
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The impact of neurological disability and sensory loss on mindfulness practice by Finlay, K. A., Hearn, J. H., Chater, A.

“…Mindfulness-based approaches are increasingly recommended in the management of medical conditions associated with sensory loss and absence, such as Spinal Cord…”
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Turing-like mechanism in a stochastic reaction-diffusion model recreates three dimensional vascular patterning of plant stems by Hearn, David J

“…Vascular tissue in plants provides a resource distribution network for water and nutrients that exhibits remarkable diversity in patterning among different…”
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Interventions and outcomes of patients with multiple myeloma receiving salvage therapy after BCMA-directed CAR T therapy by Van Oekelen, Oliver, Nath, Karthik, Mouhieddine, Tarek H., Farzana, Tasmin, Aleman, Adolfo, Melnekoff, David T., Ghodke-Puranik, Yogita, Shah, Gunjan L., Lesokhin, Alexander, Giralt, Sergio, Thibaud, Santiago, Rossi, Adriana, Rodriguez, Cesar, Sanchez, Larysa, Richter, Joshua, Richard, Shambavi, Cho, Hearn J., Chari, Ajai, Usmani, Saad Z., Jagannath, Sundar, Shah, Urvi A., Mailankody, Sham, Parekh, Samir

“…•In a cohort of 79 patients relapsing after BCMA-directed CAR T, multiple lines of salvage therapy led to a median overall survival of 17.9 months.•In 35…”
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Circadian Entrainment in Arabidopsis by the Sugar-Responsive Transcription Factor bZIP63 by Frank, Alexander, Matiolli, Cleverson C., Viana, Américo J.C., Hearn, Timothy J., Kusakina, Jelena, Belbin, Fiona E., Wells Newman, David, Yochikawa, Aline, Cano-Ramirez, Dora L., Chembath, Anupama, Cragg-Barber, Kester, Haydon, Michael J., Hotta, Carlos T., Vincentz, Michel, Webb, Alex A.R., Dodd, Antony N.

“…Synchronization of circadian clocks to the day-night cycle ensures the correct timing of biological events. This entrainment process is essential to ensure…”
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Immunophenotypic correlates of sustained MRD negativity in patients with multiple myeloma by Coffey, David G., Maura, Francesco, Gonzalez-Kozlova, Edgar, Diaz-Mejia, J. Javier, Luo, Ping, Zhang, Yong, Xu, Yuexin, Warren, Edus H., Dawson, Travis, Lee, Brian, Xie, Hui, Smith, Eric, Ciardiello, Amanda, Cho, Hearn J., Rahman, Adeeb, Kim-Schulze, Seunghee, Diamond, Benjamin, Lesokhin, Alexander, Kazandjian, Dickran, Pugh, Trevor J., Green, Damian J., Gnjatic, Sacha, Landgren, Ola

“…The role of the immune microenvironment in maintaining disease remission in patients with multiple myeloma (MM) is not well understood. In this study, we…”
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Function and evolution of ‘green’ GSK3/Shaggy-like kinases by Saidi, Younousse, Hearn, Timothy J, Coates, Juliet C

“…Glycogen synthase kinase 3 (GSK3) proteins, also known as SHAGGY-like kinases, have many important cell signalling roles in animals, fungi and amoebae. In…”
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Contribution of the TCRβ Repertoire to Marek's Disease Genetic Resistance in the Chicken by Hearn, Cari J, Cheng, Hans H

“…Marek's disease (MD) is a lymphoproliferative disease of chickens induced by Marek's disease virus (MDV), an oncogenic α-herpesvirus. MDV has increased in…”
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Brood ball-mediated transmission of microbiome members in the dung beetle, Onthophagus taurus (Coleoptera: Scarabaeidae) by Estes, Anne M, Hearn, David J, Snell-Rood, Emilie C, Feindler, Michele, Feeser, Karla, Abebe, Tselotie, Dunning Hotopp, Julie C, Moczek, Armin P

“…Insects feeding on plant sap, blood, and other nutritionally incomplete diets are typically associated with mutualistic bacteria that supplement missing…”
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Altered N-methyl D-aspartate receptor subunit expression causes changes to the circadian clock and cell phenotype in osteoarthritic chondrocytes by Kalev-Zylinska, M.L., Hearn, J.I., Rong, J., Zhu, M., Munro, J., Cornish, J., Dalbeth, N., Poulsen, R.C.

“…The chondrocyte circadian clock is altered in osteoarthritis. This change is implicated in the disease-associated changes in chondrocyte phenotype and…”
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Bispecific Antibodies in Multiple Myeloma: Present and Future by Lancman, Guido, Sastow, Dahniel L, Cho, Hearn J, Jagannath, Sundar, Madduri, Deepu, Parekh, Samir S, Richard, Shambavi, Richter, Joshua, Sanchez, Larysa, Chari, Ajai

“…Despite many recent advances in therapy, there is still no plateau in overall survival curves in multiple myeloma. Bispecific antibodies are a novel…”
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A Systematic Review of Utilisation of Diurnal Timing Information in Clinical Trial Design for Long QT Syndrome by Seed, Lydia M, Hearn, Timothy J

“…Diurnal oscillations in human cardiac electrophysiology are thought to be under the control of the endogenous circadian clock. The incidence of arrhythmic…”
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Simulating impacts of rapid forest loss on population size, connectivity and genetic diversity of Sunda clouded leopards (Neofelis diardi) in Borneo by Macdonald, Ewan A, Cushman, Samuel A, Landguth, Erin L, Hearn, Andrew J, Malhi, Yadvinder, Macdonald, David W

“…Habitat loss is the greatest threat to biodiversity in Borneo, and to anticipate and combat its effects it is important to predict the pattern of loss and its…”
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Activity patterns and temporal avoidance by prey in response to Sunda clouded leopard predation risk by Ross, J., Hearn, A. J., Johnson, P. J., Macdonald, D. W.

“…Little is known about the activity patterns of Bornean ungulates, or the temporal interactions of these species with the Sunda clouded leopard Neofelis diardi…”
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The immune cell landscape and response of Marek’s disease resistant and susceptible chickens infected with Marek’s disease virus by Warren, Wesley C., Rice, Edward S., Meyer, Ashley, Hearn, Cari J., Steep, Alec, Hunt, Henry D., Monson, Melissa S., Lamont, Susan J., Cheng, Hans H.

“…Genetically resistant or susceptible chickens to Marek’s disease (MD) have been widely used models to identify the molecular determinants of these phenotypes…”
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Multi-omic analysis of the tumor microenvironment shows clinical correlations in Ph1 study of atezolizumab +/- SoC in MM by Wong, Sandy, Hamidi, Habib, Costa, Luciano J, Bekri, Selma, Neparidze, Natalia, Vij, Ravi, Nielsen, Tina G, Raval, Aparna, Sareen, Rajan, Wassner-Fritsch, Elisabeth, Cho, Hearn J

“…Multiple myeloma (MM) remains incurable, and treatment of relapsed/refractory (R/R) disease is challenging. There is an unmet need for more targeted therapies…”
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