Search Results - "Heard, David M"

Electrode Materials in Modern Organic Electrochemistry by Heard, David M., Lennox, Alastair J. J.

“…The choice of electrode material is critical for achieving optimal yields and selectivity in synthetic organic electrochemistry. The material imparts…”
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ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease by Evans, Charles E., Miners, James S., Piva, Giulia, Willis, Christine L., Heard, David M., Kidd, Emma J., Good, Mark A., Kehoe, Patrick G.

“…Mid-life hypertension and cerebrovascular dysfunction are associated with increased risk of later life dementia, including Alzheimer’s disease (AD). The…”
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Open‐ESyn: A 3D‐Printed Toolkit for Expanded ElectraSyn Functionality and Reproducibility for Electrosynthesis by Choi, Anthony, Heard, David M., Haydon, Calum S., Lennox, Alastair J. J.

“…Electrosynthetic reactions are performed in either custom‐made reactors that are developed and machined in‐house or commercially available systems that offer…”
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Uncovering biosynthetic relationships between antifungal nonadrides and octadrides by de Mattos-Shipley, Kate M. J, Spencer, Catherine E, Greco, Claudio, Heard, David M, O'Flynn, Daniel E, Dao, Trong T, Song, Zhongshu, Mulholland, Nicholas P, Vincent, Jason L, Simpson, Thomas J, Cox, Russell J, Bailey, Andrew M, Willis, Christine L

“…Maleidrides are a class of bioactive secondary metabolites unique to filamentous fungi, which contain one or more maleic anhydrides fused to a 7-, 8- or 9-…”
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Electrode Materials in Modern Organic Electrochemistry by Heard, David M., Lennox, Alastair J. J.

“…The choice of electrode material is critical for achieving optimal yields and selectivity in synthetic organic electrochemistry. The material imparts…”
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Electrochemical Benzylic C(sp3)–H Acyloxylation by Atkins, Alexander P., Rowett, Albert C., Heard, David M., Tate, Joseph A., Lennox, Alastair J. J.

“…The development of sustainable C­(sp3)–H functionalization methods is of great interest to the pharmaceutical and agrochemical industries. Anodic oxidation is…”
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200 Years of The Haloform Reaction: Methods and Applications by Rowett, Albert C, Heard, David M, Koria, Priya, Dean, Alice C, Sweeting, Stephen G, Lennox, Alastair J J

“…Discovered in 1822, the haloform reaction is one of the oldest synthetic organic reactions. The haloform reaction enables the synthesis of carboxylic acids,…”
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A Stoichiometric Haloform Coupling for Ester Synthesis with Secondary Alcohols by Rowett, Albert C., Sweeting, Stephen G., Heard, David M., Lennox, Alastair J. J.

“…The haloform reaction from methyl ketones to carboxylic acids is one of the oldest known synthetic organic reactions, which has been used in myriad…”
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Dichloromeldrum’s Acid (DiCMA): A Practical and Green Amine Dichloroacetylation Reagent by Heard, David M, Lennox, Alastair J. J

“…Dichloromeldrum’s acid is introduced as a bench-stable, nonvolatile reagent for the dichloroacetylation of anilines and alkyl amines to produce…”
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Minimal manual input by Heard, David M., Lennox, Alastair J. J.

“…Synthetic organic chemistry is increasingly automated, data rich and intelligent. At the Automated Synthesis Forum, industry and academia showcased their…”
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3D Printed Reactionware for Synthetic Electrochemistry with Hydrogen Fluoride Reagents by Heard, David M., Doobary, Sayad, Lennox, Alastair J. J.

“…Electrochemical fluorination reactions of organic compounds frequently employ hydrogen fluoride reagents that are corrosive. The corrosive nature of these…”
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A Stoichiometric Haloform Coupling for Ester Synthesis with Secondary Alcohols by Rowett, Albert C., Sweeting, Stephen G., Heard, David M., Lennox, Alastair J. J.

“…The haloform reaction from methyl ketones to carboxylic acids is one of the oldest known synthetic organic reactions, which has been used in myriad…”
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The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis by de Mattos-Shipley, Kate M J, Greco, Claudio, Heard, David M, Hough, Gemma, Mulholland, Nicholas P, Vincent, Jason L, Micklefield, Jason, Simpson, Thomas J, Willis, Christine L, Cox, Russell J, Bailey, Andrew M

“…The cycloaspeptides are bioactive pentapeptides produced by various filamentous fungi, which have garnered interest from the agricultural industry due to the…”
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Correction to: ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease by Evans, Charles E., Miners, James S., Piva, Giulia, Willis, Christine L., Heard, David M., Kidd, Emma J., Good, Mark A., Kehoe, Patrick G.

“…Unfortunately, the acknowledgement section was not included in the original publication…”
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ERCAD: A Parametric Reactor Design Tool That Enables Rapid Prototyping and Optimization of Electrochemical Reactors through 3D Printing by Heard, David M., Deeks, Sam W., Lennox, Alastair J. J.

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Structural and synthetic studies on maleic anhydride and related diacid natural products by Heard, David M., Tayler, Emyr R., Cox, Russell J., Simpson, Thomas J., Willis, Christine L.

“…A concise approach has been developed for the total syntheses of tricladic acids A, B and C previously isolated from Tricladium castaneicola confirming the…”
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Correction to: ACE2 activation protects against cognitive decline and reducesamyloid pathology in the Tg2576 mouse model of Alzheimer’s disease by Evans, Charles E, Miners, James S, Piva Giulia, Willis, Christine L, Heard, David M, Kidd, Emma J, Good, Mark A, Kehoe, Patrick G

“…Unfortunately, the acknowledgement section was not included in the original publication…”
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The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesisElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00717a by de Mattos-Shipley, Kate M. J, Greco, Claudio, Heard, David M, Hough, Gemma, Mulholland, Nicholas P, Vincent, Jason L, Micklefield, Jason, Simpson, Thomas J, Willis, Christine L, Cox, Russell J, Bailey, Andrew M

“…The cycloaspeptides are bioactive pentapeptides produced by various filamentous fungi, which have garnered interest from the agricultural industry due to the…”
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The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00717a by de Mattos-Shipley, Kate M. J., Greco, Claudio, Heard, David M., Hough, Gemma, Mulholland, Nicholas P., Vincent, Jason L., Micklefield, Jason, Simpson, Thomas J., Willis, Christine L., Cox, Russell J., Bailey, Andrew M.

“…The cycloaspeptide gene cluster includes a pathway-specific N -methyl transferase. Its disruption allowed incorporation of N -methylated amino acids provided…”
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