Search Results - "Heaps, Amy L."

Brief Report: HIV Drug Resistance Assessment Among Women Who Seroconverted During the MTN-025/HOPE Open-Label Extension Dapivirine Vaginal Ring Trial by Parikh, Urvi M, Penrose, Kerri J, Heaps, Amy L, Sethi, Rahil, Goetz, B Jay, Szydlo, Daniel, Chandran, Uma, Palanee-Phillips, Thesla, Mgodi, Nyaradzo M, Baeten, Jared M, Mellors, John W

“…Clinical trials of dapivirine (DPV) vaginal ring have shown it is safe, effective, and desired by women as an HIV prevention option. The risk of drug…”
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Rapid determination of SARS-CoV-2 antibody neutralization titer using Bio-Rad Bio-Plex correlates strongly with pseudovirus-determined neutralization titer by Heaps, Amy L., Sobolewski, Michele D., Jacobs, Jana L., Gordon, Kelley C., Haidar, Ghady, Mellors, John W., Parikh, Urvi M.

“…Accurate and rapid evaluation of SARS-CoV-2 half-maximal neutralizing antibody (nAb) titer (NT50) is an important research tool for measuring nAb responses…”
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Clinical and Virologic Outcomes Following Initiation of Antiretroviral Therapy Among Seroconverters in the Microbicide Trials Network-020 Phase III Trial of the Dapivirine Vaginal Ring by Riddler, Sharon A, Balkus, Jennifer E, Parikh, Urvi M, Mellors, John W, Akello, Carolyne, Dadabhai, Sufia, Mhlanga, Felix, Ramjee, Gita, Mayo, Ashley J, Livant, Edward, Heaps, Amy L, O'Rourke, Colin, Baeten, Jared M

“…A vaginal ring containing dapivirine, a non-nucleoside human immunodeficiency virus (HIV)-1 reverse transcriptase inhibitor (NNRTI), was safe and effective in…”
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HIV‐1 drug resistance among individuals who seroconverted in the ASPIRE dapivirine ring trial by Parikh, Urvi M., Penrose, Kerri J., Heaps, Amy L., Halvas, Elias K., Goetz, B. Jay, Gordon, Kelley C., Hardesty, Russell, Sethi, Rahil, Schwarzmann, William, Szydlo, Daniel W., Husnik, Marla J., Chandran, Uma, Palanee‐Phillips, Thesla, Baeten, Jared M., Mellors, John W.

“…Introduction A potential concern with the use of dapivirine (DPV) for HIV prevention is the selection of a drug‐resistant virus that could spread and reduce…”
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First Case of HIV Seroconversion With Integrase Resistance Mutations on Long-Acting Cabotegravir for Prevention in Routine Care by Koss, Catherine A, Gandhi, Monica, Halvas, Elias K, Okochi, Hideaki, Chu, Carolyn, Glidden, David V, Georgetti Gomez, Lisa, Heaps, Amy L, Conroy, Amy A, Tran, Michael, Shetler, Cory, Hoeth, Dianna, Kuncze, Karen, Louie, Alexander, Rivera Garza, Hana, Wafula Mugoma, Erick, Penrose, Kerri J, Chohan, Bhavna H, Ayieko, James O, Mills, Anthony, Patel, Rupa R, Mellors, John W, Parikh, Urvi M

“…Abstract Background Long-acting cabotegravir (CAB-LA) is highly effective for HIV prevention, but delayed HIV diagnoses and integrase strand transfer inhibitor…”
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Comparison Study of the Bio-Plex and Meso Scale Multiplexed SARS-CoV-2 Serology Assays Reveals Evidence of Diminished Host Antibody Responses to SARS-CoV-2 after Monoclonal Antibody Treatment by Parikh, Urvi M, Heaps, Amy L, Moisi, Daniela, Gordon, Kelley C, Mellors, John W, Choudhary, Manish C, Deo, Rinki, Moser, Carlee, Klekotka, Paul, Landay, Alan L, Currier, Judith S, Eron, Joseph J, Chew, Kara W, Smith, Davey M, Li, Jonathan Z, Sieg, Scott F

“…Assessing the breadth and duration of antigen-specific binding antibodies provides valuable information for evaluating interventions to treat or prevent…”
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Rapid Emergence of Potentially Transmissible Severe Acute Respiratory Syndrome Coronavirus 2 With Resistance to Combination Monoclonal Antibody Therapy by Jacobs, Jana L, Haidar, Ghady, Naqvi, Asma, McCormick, Kevin D, Sobolewski, Michele, Treat, Benjamin R, Heaps, Amy L, Simpson, Jordan, Kramer, Kailey Hughes, McCreary, Erin, Bariola, J Ryan, Klamar-Blain, Cynthia, Macatangay, Bernard J C, Dimitrov, Dimiter, Li, Wei, Marino, Christopher C, Raptis, Anastasios, Sethi, Rahil, Chandran, Uma, Barratt-Boyes, Simon, Parikh, Urvi M, Mellors, John W

“…Abstract Prolonged coronavirus disease 2019 may generate new viral variants. We report an immunocompromised patient treated with monoclonal antibodies who…”
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Impact of SARS-CoV-2 Resistance to Antiviral Monoclonal Antibody Therapy on Neutralizing Antibody Response by Paul, Marc-Kendy, Choudhary, Manish C, Heaps, Amy L, Deo, Rinki, Moisi, Daniela, Gordon, Kelley C, Mellors, John W, Moser, Carlee, Klekotka, Paul, Landay, Alan, Currier, Judith S, Eron, Joseph J, Chew, Kara W, Smith, Davey M, Sieg, Scott F, Parikh, Urvi M, Li, Jonathan Z

“…Anti-SARS-CoV-2 monoclonal antibodies (mAbs) have played a key role as an anti-viral against SARS-CoV-2, but there is a potential for resistance to develop…”
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