Search Results - "Heaney, Anthony"

Pituitary Carcinoma: Difficult Diagnosis and Treatment by Heaney, Anthony P

“…Context: Although pituitary tumors are common, pituitary carcinoma is very rare and is only diagnosed when pituitary tumor noncontiguous with the sellar region…”
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Testicular Receptor-4: Novel Regulator of Glucocorticoid Resistance by Zhang, Dongyun, Du, Li, Heaney, Anthony P

“…Context: Glucocorticoids are powerful steroid hormones that regulate development, metabolism, and immune response. However, glucocorticoid unresponsiveness or…”
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Appropriate Use Criteria for Somatostatin Receptor PET Imaging in Neuroendocrine Tumors by Hope, Thomas A, Bergsland, Emily K, Bozkurt, Murat Fani, Graham, Michael, Heaney, Anthony P, Herrmann, Ken, Howe, James R, Kulke, Matthew H, Kunz, Pamela L, Mailman, Josh, May, Lawrence, Metz, David C, Millo, Corina, O'Dorisio, Sue, Reidy-Lagunes, Diane L, Soulen, Michael C, Strosberg, Jonathan R

“…Somatostatin receptor (SSTR) PET has demonstrated a significant improvement over conventional imaging (CI) in patients with neuroendocrine tumors (NETs). SSTR…”
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Targeting Corticotroph HDAC and PI3-Kinase in Cushing Disease by Zhang, Dongyun, Damoiseaux, Robert, Babayan, Lilit, Rivera-Meza, Everett Kanediel, Yang, Yingying, Bergsneider, Marvin, Wang, Marilene B, Yong, William H, Kelly, Kathleen, Heaney, Anthony P

“…Abstract Context Cushing disease (CD) is a life-threatening disorder. Therapeutic goals include symptom relief, biochemical control, and tumor growth…”
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Low Cortisol in a Cushingoid Patient by Song, Lu, Sue, Laura Y, Heaney, Anthony P

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Whole-exome sequencing reveals genetic variants that may play a role in neurocytomas by Khowal, Sapna, Zhang, Dongyun, Yong, William H, Heaney, Anthony P.

“…Objectives Neurocytomas (NCs) are rare intracranial tumors that can often be surgically resected. However, disease course is unpredictable in many patients and…”
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Effect of Everolimus in Treatment of Aggressive Prolactin-Secreting Pituitary Adenomas by Zhang, Dongyun, Way, Jennifer S, Zhang, Xinhai, Sergey, Mareninov, Bergsneider, Marvin, Wang, Marilene B, Yong, William H, Heaney, Anthony P

“…Abstract Context Aggressive prolactin (PRL)-secreting pituitary adenomas that are resistant to conventional therapy with dopamine agonists, surgery, and…”
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Single-cell RNA sequencing in silent corticotroph tumors confirms impaired POMC processing and provides new insights into their invasive behavior by Zhang, Dongyun, Hugo, Willy, Bergsneider, Marvin, Wang, Marilene B, Kim, Won, Vinters, Harry V, Heaney, Anthony P

“…Objective Provide insights into the defective POMC processing and invasive behavior in silent pituitary corticotroph tumors. Design and methods Single-cell…”
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Targeted systemic and peptide radio-ligand therapy for aggressive pituitary tumors and carcinomas by Petersenn, Stephan, Heaney, Anthony P.

“…Aggressive pituitary tumors comprise a rare but challenging subset of pituitary tumors. A major issue currently is the absence of a holistic definition that…”
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Randomized Trial of Osilodrostat for the Treatment of Cushing Disease by Gadelha, Mônica, Bex, Marie, Feelders, Richard A, Heaney, Anthony P, Auchus, Richard J, Gilis-Januszewska, Aleksandra, Witek, Przemyslaw, Belaya, Zhanna, Yu, Yerong, Liao, Zhihong, Ku, Chih Hao Chen, Carvalho, Davide, Roughton, Michael, Wojna, Judi, Pedroncelli, Alberto M, Snyder, Peter J

“…Cushing disease, a chronic hypercortisolism disorder, is associated with considerable morbidity and mortality. Normalizing cortisol production is the primary…”
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Regulation of Adipose Differentiation by Fructose and GluT5 by Du, Li, Heaney, Anthony P

“…Adipose tissue is an important metabolic organ that is crucial for whole-body insulin sensitivity and energy homeostasis. Highly refined fructose intake…”
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Multidisciplinary management of acromegaly: A consensus by Giustina, Andrea, Barkhoudarian, Garni, Beckers, Albert, Ben-Shlomo, Anat, Biermasz, Nienke, Biller, Beverly, Boguszewski, Cesar, Bolanowski, Marek, Bollerslev, Jens, Bonert, Vivien, Bronstein, Marcello D., Buchfelder, Michael, Casanueva, Felipe, Chanson, Philippe, Clemmons, David, Fleseriu, Maria, Formenti, Anna Maria, Freda, Pamela, Gadelha, Monica, Geer, Eliza, Gurnell, Mark, Heaney, Anthony P., Ho, Ken K. Y., Ioachimescu, Adriana G., Lamberts, Steven, Laws, Edward, Losa, Marco, Maffei, Pietro, Mamelak, Adam, Mercado, Moises, Molitch, Mark, Mortini, Pietro, Pereira, Alberto M., Petersenn, Stephan, Post, Kalmon, Puig-Domingo, Manuel, Salvatori, Roberto, Samson, Susan L., Shimon, Ilan, Strasburger, Christian, Swearingen, Brooke, Trainer, Peter, Vance, Mary L., Wass, John, Wierman, Margaret E., Yuen, Kevin C. J., Zatelli, Maria Chiara, Melmed, Shlomo

“…The 13th Acromegaly Consensus Conference was held in November 2019 in Fort Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and…”
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The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors by Strosberg, Jonathan R, Halfdanarson, Thorvardur R, Bellizzi, Andrew M, Chan, Jennifer A, Dillon, Joseph S, Heaney, Anthony P, Kunz, Pamela L, O'Dorisio, Thomas M, Salem, Riad, Segelov, Eva, Howe, James R, Pommier, Rodney F, Brendtro, Kari, Bashir, Mohammad A, Singh, Simron, Soulen, Michael C, Tang, Laura, Zacks, Jerome S, Yao, James C, Bergsland, Emily K

“…There have been significant developments in diagnostic and therapeutic options for patients with neuroendocrine tumors (NETs). Key phase 3 studies include the…”
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Cabergoline targets multiple pathways to inhibit PRL secretion and increases stromal fibrosis by Zhang, Dongyun, Hugo, Willy, Bergsneider, Marvin, Wang, Marilene B, Kim, Won, Han, Karam, Vinters, Harry V, Heaney, Anthony P

“…Unravel the potential mechanism(s) of the on- and off-target actions of dopamine agonist therapy in both human prolactinoma tumors and neighboring stromal and…”
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Consensus on biomarkers for neuroendocrine tumour disease by Oberg, Kjell, Prof, Modlin, Irvin M, Prof, De Herder, Wouter, Prof, Pavel, Marianne, Prof, Klimstra, David, Prof, Frilling, Andrea, Prof, Metz, David C, Prof, Heaney, Anthony, MD, Kwekkeboom, Dik, MD, Strosberg, Jonathan, MD, Meyer, Timothy, Prof, Moss, Steven F, Prof, Washington, Kay, Prof, Wolin, Edward, Prof, Liu, Eric, MD, Goldenring, James, Prof

“…Summary Management of neuroendocrine neoplasia represents a clinical challenge because of its late presentation, lack of treatment options, and limitations in…”
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Fructose Induces Transketolase Flux to Promote Pancreatic Cancer Growth by HAIBO LIU, DANSHAN HUANG, MCARTHUR, David L, BOROS, Laszlo G, NISSEN, Nicholas, HEANEY, Anthony P

“…Carbohydrate metabolism via glycolysis and the tricarboxylic acid cycle is pivotal for cancer growth, and increased refined carbohydrate consumption adversely…”
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A tale of pituitary adenomas: to NET or not to NET: Pituitary Society position statement by Ho, Ken K. Y., Fleseriu, Maria, Wass, John, van der Lely, Aart, Barkan, Ariel, Giustina, Andrea, Casanueva, Felipe F., Heaney, Anthony P., Biermasz, Nienke, Strasburger, Christian, Melmed, Shlomo

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HLA Markers DQ8 and DR53 Are Associated With Lymphocytic Hypophysitis and May Aid in Differential Diagnosis by Heaney, Anthony P, Sumerel, Brittany, Rajalingam, Raja, Bergsneider, Marvin, Yong, William H, Liau, Linda M

“…Importance: Lymphocytic hypophysitis (LH) is a poorly understood autoimmune disorder of the pituitary gland. Symptoms include headache, pituitary dysfunction,…”
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Corticotroph tumor progression after bilateral adrenalectomy (Nelson’s syndrome): systematic review and expert consensus recommendations by Reincke, Martin, Albani, Adriana, Assie, Guillaume, Bancos, Irina, Brue, Thierry, Buchfelder, Michael, Chabre, Olivier, Ceccato, Filippo, Daniele, Andrea, Detomas, Mario, Di Dalmazi, Guido, Elenkova, Atanaska, Findling, James, Grossman, Ashley B, Gomez-Sanchez, Celso E, Heaney, Anthony P, Honegger, Juergen, Karavitaki, Niki, Lacroix, Andre, Laws, Edward R, Losa, Marco, Murakami, Masanori, Newell-Price, John, Pecori Giraldi, Francesca, Pérez‐Rivas, Luis G, Pivonello, Rosario, Rainey, William E, Sbiera, Silviu, Schopohl, Jochen, Stratakis, Constantine A, Theodoropoulou, Marily, van Rossum, Elisabeth F C, Valassi, Elena, Zacharieva, Sabina, Rubinstein, German, Ritzel, Katrin

“…Background Corticotroph tumor progression (CTP) leading to Nelson’s syndrome (NS) is a severe and difficult-to-treat complication subsequent to bilateral…”
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Effect of 3 NR3C1 Mutations in the Pathogenesis of Pituitary ACTH Adenoma by Miao, Hui, Liu, Yang, Lu, Lin, Gong, Fengying, Wang, Linjie, Duan, Lian, Yao, Yong, Wang, Renzhi, Chen, Shi, Mao, Xinxin, Zhang, Dongyun, Heaney, Anthony P, Zhu, Huijuan

“…Glucocorticoids act through the glucocorticoid receptor (GR) encoded by the nuclear receptor subfamily 3 group C member 1 (NR3C1) gene. This study aimed to…”
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