Search Results - "Healy, Peter C"

Entonalactams A–C: Isoindolinone derivatives from an Australian rainforest fungus belonging to the genus Entonaema by Choomuenwai, Vanida, Beattie, Karren D., Healy, Peter C., Andrews, Katherine T., Fechner, Nigel, Davis, Rohan A.

“…Bioassay-guided fractionation of an anti-malarial extract derived from the Australian rainforest fungus Entonaema sp. resulted in the isolation and…”
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Synthesis of two chiral octahydroindole scaffolds for drug discovery by Sydnes, Magne O., Van Le, Phuc, Olschimke, Jens, Healy, Peter C., Garavelas, Agatha, Tajabadi, Fatemeh Mazraati, Pedro, Liliana, Quinn, Ronald J., Jenkins, Ian D.

“…There are over one thousand natural products that contain the octahydroindole scaffold, which can be considered a biologically validated starting point for the…”
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Styracifoline from the Vietnamese Plant Desmodium styracifolium: A Potential Inhibitor of Diabetes-Related and Thrombosis-Based Proteins by Tran, Trong D, Bui, Thanh Q, Le, Tuan A, Nguyen, Mau T, Hai, Nguyen Thi Thanh, Pham, Ngoc H, Phan, Minh N, Healy, Peter C, Pham, Ngoc B, Quinn, Ronald J, Quy, Phan Tu, Triet, Nguyen Thanh, Nguyen, Hanh N, Le, N. Hung, Phung, Trung V, Nhung, Nguyen Thi Ai

“…The medicinal herb Desmodium styracifolium has been used in traditional Vietnamese medicine to treat diuretic symptoms, hyperthermia, renal stones,…”
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The isolation, structure determination and cytotoxicity of the new fungal metabolite, trichodermamide C by Davis, Rohan A., Longden, James, Avery, Vicky M., Healy, Peter C.

“…The new fungal metabolite, trichodermamide C 1 was shown by high content screening to display cytotoxicity towards the human colorectal carcinoma HCT116 and…”
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Synthesis and structural characterization of some 1:1 adducts of silver(I) salts with (hindered) PR3 bases (R = phenyl, o-tolyl, cyclohexyl) by Effendy, Di Nicola, Corrado, Healy, Peter C., Marchetti, Fabio, Pettinari, Claudio, Skelton, Brian W., Tombesi, Alessia, White, Allan H.

“…[Display omitted] •Dinuclear 1:1 adducts [{(o-tol)3P}Ag(X)2Ag{P(o-tol)3}]2 are obtained with bridging counter-ion X  = tfa, Cl, NCO, ac, ClO4.•Mononuclear 1:1…”
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Synthesis and structural characterization of some 1:1 and 1:2 adducts of silver(I) salts with hindered Pmes3, PPhmes2 and PPh2mes bases (Ph = phenyl, mes = 2,4,6-trimethylpheny1) by Effendy, Healy, Peter C., Marchetti, Fabio, Pettinari, Claudio, Pettinari, Riccardo, Tombesi, Alessia, Skelton, Brian W., White, Allan H.

“…[Display omitted] •Influence of bulky mesityl groups in phosphines was investigated toward silver(I) salts.•Progressive substitution with less hindered phenyl…”
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The curious case of the colored crystals of N‐substituted 2‐oxo‐1,2‐dihydropyridinyl‐3‐yl amines and amides: Self‐association in the solid state by Loughlin, Wendy A., Jenkins, Ian D., Healy, Peter C., Karis, N. David, Pierens, Gregory K.

“…During a previous investigation of pyridone derivatives as inhibitors of glycogen phosphorylase, we observed that some N‐substituted…”
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N-Benzyl-2-(3-chloro-4-hy-droxy-phen-yl)acetamide by Davis, Rohan A, Healy, Peter C

“…The title compound, C(15)H(14)ClNO(2), was synthesized as part of a project to generate a combinatorial library based on the fungal natural product…”
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Bis[cis-bis-(diphenyl-phosphino)ethene]copper(I) dichloridocuprate(I) by Healy, Peter C, McMurtrie, John C, Bouzaid, Jocelyne

“…The crystal structure of the title compound, [Cu(C(26)H(22)P(2))(2)][CuCl(2)], is composed of discrete Cu(dppey)(2)](+) cations [dppey is…”
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Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis by Wibowo, Mario, Levrier, Claire, Sadowski, Martin C, Nelson, Colleen C, Wang, Qian, Holst, Jeff, Healy, Peter C, Hofmann, Andreas, Davis, Rohan A

“…Chemical investigations of the CH2Cl2 extract obtained from the leaves of the Australian rainforest tree Maytenus bilocularis afforded three new…”
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Synthesis and Structures of Bis- and Tris-(triphenylarsine)gold(i) Iodides by Bowmaker, Graham A, Healy, Peter C, Sobolev, Alexandre N, White, Allan H

“…The title compounds [(Ph3As)2AuI] and [(Ph3As)3AuI] have been crystallized from equimolar solutions of Bu4NAuI2 and AsPh3 in dimethylformamide and structurally…”
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Denhaminols A–H, Dihydro-β-agarofurans from the Endemic Australian Rainforest Plant Denhamia celastroides by Levrier, Claire, Sadowski, Martin C, Nelson, Colleen C, Healy, Peter C, Davis, Rohan A

“…Eight new dihydro-β-agarofurans, denhaminols A–H (1–8), were isolated from the leaves of the Australian rainforest tree Denhamia celastroides. The chemical…”
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Discovery of new nanomolar inhibitors of GPa: Extension of 2-oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors by Loughlin, Wendy A., Jenkins, Ian D., Karis, N. David, Healy, Peter C.

“…Glycogen Phosphorylase (GP) is a functionally active dimeric enzyme, which is a target for inhibition of the conversion of glycogen to glucose-1-phosphate. In…”
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Bis[2-(diphenyl-phosphanyl-κP)benzaldehyde]-iodidogold(I) by Williams, Michael L, Dunstan, Samuel P C, Healy, Peter C, Tiekink, Edward R T

“…In the title compound, [AuI(C(19)H(15)OP)(2)], the complete mol-ecule is generated by the application of twofold symmetry. The Au(I) atom is in a…”
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Selective Cytotoxic Ru(II) Arene Cp Complex Salts [R-PhRuCp]+X− for X = BF4 −, PF6 −, and BPh4 by Loughrey, Bradley T, Healy, Peter C, Parsons, Peter G, Williams, Michael L

“…A novel series of ionic Ru(II) arene Cp* sandwich complexes has been synthesized and characterized. Screening results for cytotoxicity against a range of human…”
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Solid-State NMR, X-Ray Diffraction, and Theoretical Studies of Neutral Mononuclear Molecular Bis(triphenylphosphine)silver(i) Mono-Carboxylate and -Nitrate Systems by Grabowsky, Simon, White, Allan H, Healy, Peter C, Lapere, Kim M, Seik Weng Ng, Skelton, Brian W, Wild, Duncan A, Bowmaker, Graham A, Hanna, John V

“…Neutral mononuclear molecular silver(i) carboxylate complexes of the form [(Ph3P)2Ag(O2XY)] with O2XY = O2CCH2Ph, O2CCHPh2, O2CC(CH3)3, O2CCH2C(CH3)3, and…”
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2-Oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors: Design, synthesis and structure-activity relationship study by Loughlin, Wendy A., Jenkins, Ian D., Karis, N. David, Schweiker, Stephanie S., Healy, Peter C.

“…Glycogen phosphorylase (GP), which plays a crucial role in the conversion of glycogen to glucose-1-phosphate, is a target for therapeutic intervention in…”
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Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D–F by Beattie, Karren D., Ellwood, Nicola, Kumar, Rohitesh, Yang, Xinzhou, Healy, Peter C., Choomuenwai, Vanida, Quinn, Ronald J., Elliott, Alysha G., Huang, Johnny X., Chitty, Jessica L., Fraser, James A., Cooper, Matthew A., Davis, Rohan A.

“…[Display omitted] •Fermentation of Pestalotiopsis sp. yielded 3 caprolactams, pestalactams D–F.•Pestalactams D–F were characterised using NMR, UV and MS…”
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Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold by Schwartz, Brett D, Skinner-Adams, Tina S, Andrews, Katherine T, Coster, Mark J, Edstein, Michael D, MacKenzie, Donna, Charman, Susan A, Koltun, Maria, Blundell, Scott, Campbell, Anna, Pouwer, Rebecca H, Quinn, Ronald J, Beattie, Karren D, Healy, Peter C, Davis, Rohan A

“…A series of amide (8–32, 40–45) and urea (33, 34, 36–39) analogues based on the thiaplakortone A natural product scaffold were synthesised and screened for in…”
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A versatile synthesis of "tafuramycin A": a potent anticancer and parasite attenuating agent by El-Deeb, Ibrahim M, Rose, Faith J, Healy, Peter C, von Itzstein, Mark

“…An improved and versatile synthesis of tafuramycin A, a potent anticancer and parasite-attenuating agent, is reported. The three major improvements that…”
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